Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Natsuko Uekawa"'
Autor:
Kei Kobayashi, Satoru Usami, Masakazu Kashihara, Toshiyuki Komori, Noriko Ishikawa, Rise Kum, Norio Kato, Natsuko Uekawa, Naoki Takemori, Yuejin Sun, Paul Oeller, Esteban Bortiri, Nicholas J. Bate, Toshihiko Komari, Yukoh Hiei, Kimberly White
Publikováno v:
Theoretical and Applied Genetics. 133:1291-1301
Novel drought tolerance genes were identified by screening thousands of random genomic fragments from grass species in transgenic rice. Identification of agronomically important genes is a critical step for crop breeding through biotechnology. Multip
Autor:
Noriyuki Kioka, Kazumitsu Ueda, Kenzo Takahashi, Natsuko Uekawa, Tsutomu Umemoto, Takuya Ito, Hiroshi Imai, Hideto Watanabe, Hiroshi Yamashita, Soh Motoyoshi, Masayasu Yamada
Publikováno v:
Experimental cell research. 316(10):1728-1738
In the process of tissue injury and repair, epithelial cells rapidly migrate and form epithelial sheets. Vinexin is a cytoplasmic molecule of the integrin-containing cell adhesion complex localized at focal contacts in vitro. Here, we investigated th
Autor:
Masataka Sugimoto, Kunihiko Terauchi, Natsuko Uekawa, Junichi Shimada, Takeshi Wakoh, Akihito Ishigami, Mitsuo Maruyama
Publikováno v:
Biochemical and Biophysical Research Communications. 380:807-812
A novel target of NESH-SH3 (TARSH) was identified as a cellular senescence related gene in mouse embryonic fibroblasts (MEFs) replicative senescence, the expression of which has been suppressed in primary clinical lung cancer specimens. However, the
Autor:
Wangtao Zhong, Tetsuro Miki, Noriaki Mitsuda, Masatoshi Takeda, Keiko Taguchi, Hiroyasu Akatsu, Takayuki Yamamoto, Mamoru Aoto, Mitsuo Maruyama, Kenji Kosaka, Ikuko Kondo, Hidehisa Yamagata, Kouzin Kamino, Natsuko Uekawa
Publikováno v:
Life Sciences. 78:2444-2448
Nicastrin interacts with gamma-secretase complex components predominantly via the N-terminal third of the transmembrane domain. The authentic transmembrane domain is critically required for the interaction with gamma-secretase complex components and
Autor:
Ken-ichi Isobe, Natsuko Uekawa, Akihiko Nishikimi, Nahum Meller, Mitsuo Maruyama, Martin A. Schwartz
Publikováno v:
FEBS Letters. 579:1039-1046
A novel superfamily of guanine nucleotide exchange factors for Rho GTPases includes DOCK180 and zizimin1. The zizimin subfamily includes three genes of which only zizimin1 has been cloned. We report here the cloning of zizimin2, identified in a scree
Autor:
Mitsuo Maruyama, Tomohisa Nishioka, Masataka Sugimoto, Junichi Shimada, Kunihiko Terauchi, Natsuko Uekawa, Satoshi Ohta
Publikováno v:
Hybridoma (2005). 26(6)
TARSH/Abi3bp was originally isolated as a novel target of NESH-SH3 by a two-hybrid yeast system. We have already identified murine TARSH (mTARSH) as a cellular senescence-related gene because of its robust induction in the early phase of mouse embryo
Autor:
Masataka Sugimoto, Natsuko Uekawa, Mitsuo Maruyama, Yoko Murata, Takeshi Wakoh, Azusa Asai, Tadaaki Miyazaki
Publikováno v:
FEBS letters. 580(26)
Death-associated protein 3 (DAP3) has been originally identified as a positive mediator of apoptosis. It has been revealed recently that the predominant localization of DAP3 to mitochondria implies its functional involvement in mitochondrial metaboli
Autor:
Natsuko Uekawa, Takeshi Yaoi, Kunihiko Terauchi, Mitsuo Maruyama, Shinji Fushiki, Junichi Shimada
Publikováno v:
Journal of cancer research and clinical oncology. 132(1)
Purpose: We have previously identified mouse Tarsh as one of the cellular senescence-related genes and showed the loss of expression of TARSH mRNA in four human lung cancer cell lines. TARSH is a presumptive signal transduction molecule interacting w
Publikováno v:
Biochemical and biophysical research communications. 329(3)
To reveal the molecular mechanism of cellular senescence, we have surveyed the genes that are specifically upregulated via MEFs senescence by suppression subtractive hybridization method. We show here that mTARSH was induced particularly in the relat
Involvement of IL-1 family proteins in p38 linked cellular senescence of mouse embryonic fibroblasts
Publikováno v:
FEBS letters. 575(1-3)
Senescence of mammalian cultured cells is essentially organized by a machinery of cell division and cellular stresses induced by various extracellular stimuli. Here, we show that in mouse embryonic fibroblasts (MEFs) culture in vitro, expression of a