Zobrazeno 1 - 10 of 72 pro vyhledávání: '"Natsuko Kawanishi"'
1
Akademický článek
CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value
Autor: Fang-Shu Ou, Emil Lou, Joanne Xiu, Hiroyuki Arai, Francesca Battaglin, Heinz-Josef Lenz, Richard M Goldberg, Anthony F Shields, Yasmine Baca, Philip A Philip, John L Marshall, W Michael Korn, Andreas Seeber, Natsuko Kawanishi, Jingyuan Wang, Shivani Soni, Wu Zhang, Shannon M Mumenthaler, Joshua Millstein, Priya Jayachandran, Federico Innocenti, Annika Lenz, Sandra Algaze, Taline Khoukaz, Evanthia Roussos Torres, Jim P Abraham, Benjamin A Weinberg, Alan P Venook
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background The C-C motif chemokine receptor 5 (CCR5)/C-C motif chemokine ligand 5 (CCL5) axis plays a major role in colorectal cancer (CRC). We aimed to characterize the molecular features associated with CCR5/CCL5 expression in CRC and to determine
Externí odkaz: https://doaj.org/article/0070d43d733f41d1a13e1ef74847bb8d
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2
Akademický článek
Impact of genetic variants involved in the lipid metabolism pathway on progression free survival in patients receiving bevacizumab-based chemotherapy in metastatic colorectal cancer: a retrospective analysis of FIRE-3 and MAVERICC trialsResearch in context
Autor: Jingyuan Wang, Joshua Millstein, Yan Yang, Sebastian Stintzing, Hiroyuki Arai, Francesca Battaglin, Natsuko Kawanishi, Shivani Soni, Wu Zhang, Christoph Mancao, Chiara Cremolini, Tianshu Liu, Volker Heinemann, Alfredo Falcone, Lin Shen, Heinz-Josef Lenz
Publikováno v: EClinicalMedicine, Vol 57, Iss , Pp 101827- (2023)
Summary: Background: Antiangiogenic drug (AAD)-triggered oxygen and nutrient depletion through suppression of angiogenesis switches glucose-dependent to lipid-dependent metabolism. Blocking fatty acid oxidation can enhance AAD-mediated anti-tumor eff
Externí odkaz: https://doaj.org/article/369c666a028b48c587ea629fca3a1f39
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3
Akademický článek
Immunogenic cell death pathway polymorphisms for predicting oxaliplatin efficacy in metastatic colorectal cancer
Autor: Yi Xiao, Chiara Cremolini, Fotios Loupakis, Alfredo Falcone, Natsuko Kawanishi, Christoph Mancao, Bodour Salhia, Shannon M Mumenthaler, Daniel J Weisenberger, Gangning Liang
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Immunogenic cell death (ICD) is a tumor cell death involving both innate and adaptive immune responses. Given published findings that oxaliplatin, but not irinotecan, drives ICD, we investigated whether single nucleotide polymorphisms (SNP
Externí odkaz: https://doaj.org/article/63cb3449cb6048b68ddf421f2efdf186
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4
Akademický článek
Feasibility of definitive chemoradiation therapy with nedaplatin and 5-fluorouracil in elderly patients with esophageal squamous cell carcinoma: A retrospective study
Autor: Akinori Watanabe, MD, Chikatoshi Katada, MD, PhD, Shouko Komori, MD, Hiromitsu Moriya, MD, PhD, Keishi Yamashita, MD, PhD, Hiroki Harada, MD, Mizutomo Azuma, MD, PhD, Yuki Kondo, MD, Yo Kubota, MD, Yasuaki Furue, MD, Natsuko Kawanishi, MD, Sakiko Yamane, MD, Takuya Wada, MD, Takafumi Yano, MD, Kenji Ishido, MD, PhD, Satoshi Tanabe, MD, PhD, Kazushige Hayakawa, MD, PhD, Wasaburo Koizumi, MD, PhD
Publikováno v: Advances in Radiation Oncology, Vol 3, Iss 3, Pp 305-313 (2018)
Purpose: This study was designed to retrospectively analyze the safety and efficacy of chemoradiation therapy with nedaplatin and 5-fluorouracil in elderly patients with esophageal squamous cell carcinoma. Methods and materials: Eligible patients wer
Externí odkaz: https://doaj.org/article/6072a5059f6c4577a687c29d98fe0a58
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6
Germline Polymorphisms in Genes Involved in the Antioxidant System Predict the Efficacy of Cetuximab in Metastatic Colorectal Cancer Patients Enrolled in FIRE-3 Trial
Autor: Hiroyuki Arai, Joshua Millstein, Yan Yang, Sebastian Stintzing, Jingyuan Wang, Francesca Battaglin, Natsuko Kawanishi, Priya Jayachandran, Shivani Soni, Wu Zhang, Volker Heinemann, Heinz-Josef Lenz
Publikováno v: Clinical Colorectal Cancer. 21:259-266
Reactive oxygen species activate EGFR/RAS/MAPK signaling either through the inactivation of phosphatases or by direct oxidation of kinases. We hypothesized that functional single-nucleotide polymorphisms (SNPs) in antioxidant genes link to the effica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69126ed53ae9fea42d77a31cf066a8e6
https://doi.org/10.1016/j.clcc.2022.05.005
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