Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Natsuko Goto Yamamoto"'
Autor:
Sophia Schedin-Weiss, Mitsuhiro Inoue, Lenka Hromadkova, Yasuhiro Teranishi, Natsuko Goto Yamamoto, Birgitta Wiehager, Nenad Bogdanovic, Bengt Winblad, Anna Sandebring-Matton, Susanne Frykman, Lars O. Tjernberg
Publikováno v:
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-19 (2017)
Abstract Background Increased levels of the pathogenic amyloid β-peptide (Aβ), released from its precursor by the transmembrane protease γ-secretase, are found in Alzheimer disease (AD) brains. Interestingly, monoamine oxidase B (MAO-B) activity i
Externí odkaz:
https://doaj.org/article/e013012247bd498c9c9baac88e3a9855
Autor:
Sophia Schedin-Weiss, Mitsuhiro Inoue, Yasuhiro Teranishi, Natsuko Goto Yamamoto, Helena Karlström, Bengt Winblad, Lars O Tjernberg
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63962 (2013)
Here, we present a highly sensitive method to study protein-protein interactions and subcellular location selectively for active multicomponent enzymes. We apply the method on γ-secretase, the enzyme complex that catalyzes the cleavage of the amyloi
Externí odkaz:
https://doaj.org/article/b9e640dc4365438a8b633674be6a50c6
Autor:
Lenka Hromadkova, Bengt Winblad, Lars O. Tjernberg, Birgitta Wiehager, Susanne Frykman, Anna Sandebring-Matton, Sophia Schedin-Weiss, Mitsuhiro Inoue, Nenad Bogdanovic, Natsuko Goto Yamamoto, Yasuhiro Teranishi
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-19 (2017)
Alzheimer’s Research & Therapy, Vol 9, Iss 1, Pp 1-19 (2017)
Background Increased levels of the pathogenic amyloid β-peptide (Aβ), released from its precursor by the transmembrane protease γ-secretase, are found in Alzheimer disease (AD) brains. Interestingly, monoamine oxidase B (MAO-B) activity is also in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cd3a86fdd1de124b0af5385ef9a3bd
http://hdl.handle.net/10852/63036
http://hdl.handle.net/10852/63036
Autor:
Natsuko Goto Yamamoto, Birgitta Wiehager, Mitsuhiro Inoue, Sophia Schedin-Weiss, Bengt Winblad, Taizo Ishikawa, Susanne Frykman, Yasuhiro Teranishi, Lars O. Tjernberg, Takahiro Kihara
Publikováno v:
The FEBS journal. 282(17)
γ-Secretase is a transmembrane protease complex that is responsible for the processing of a multitude of type 1 transmembrane proteins, including the amyloid precursor protein and Notch. γ-Secretase processing of amyloid precursor protein results i
Autor:
Takahiro Kihara, Yasuhiro Teranishi, Atsushi Ikeda, Susanne Frykman, Mitsuhiro Inoue, Lars O. Tjernberg, Natsuko Goto Yamamoto, Bengt Winblad, Sophia Schedin Weiss
Publikováno v:
Alzheimer's & Dementia. 10
Autor:
Bengt Winblad, Birgitta Wiehager, Natsuko Goto Yamamoto, Taizo Ishikawa, Sophia Schedin Weiss, Lars O. Tjernberg, Mitsuhiro Inoue
Publikováno v:
Alzheimer's & Dementia. 10
Background:Alzheimer’s disease (AD) is characterized by the presence of amyloid beta (Ab) plaques and neurofibrillary tangles (NFT). SPPL2b is a novel enzyme that can process TNFa and BRI2, substrates involved in Ab plaque and NFT formation. Since
Autor:
Lars O. Tjernberg, Mitsuhiro Inoue, Helena Karlström, Bengt Winblad, Yasuhiro Teranishi, Sophia Schedin-Weiss, Natsuko Goto Yamamoto
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 5, p e63962 (2013)
PLoS ONE, Vol 8, Iss 5, p e63962 (2013)
Here, we present a highly sensitive method to study protein-protein interactions and subcellular location selectively for active multicomponent enzymes. We apply the method on γ-secretase, the enzyme complex that catalyzes the cleavage of the amyloi
Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain*
Autor:
Susanne Frykman, Masakazu Hashimoto, Natsuko Goto Yamamoto, Yasuhiro Teranishi, Ji-Yeun Hur, Mitsuhiro Inoue, Takahiro Kihara, Bengt Winblad, Lars O. Tjernberg, Waltteri Hosia
In Alzheimer disease, oligomeric amyloid β-peptide (Aβ) species lead to synapse loss and neuronal death. γ-Secretase, the transmembrane protease complex that mediates the final catalytic step that liberates Aβ from its precursor protein (APP), ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5ce57b6b760be642f2681d890f2d28d
https://europepmc.org/articles/PMC3320946/
https://europepmc.org/articles/PMC3320946/
Autor:
Nenad Bogdanovic, Susanne Frykman, Takahiro Kihara, Anna Sandebring, Ji-Yeun Hur, Sophia Schedin-Weiss, Lars O. Tjernberg, Bengt Winblad, Maria Ancarcrona, Takeshi Nishimura, Yasuhiro Teranishi, Natsuko Goto Yamamoto
Publikováno v:
Neurochemistry international. 61(1)
Synaptic degeneration is one of the earliest hallmarks of Alzheimer disease (AD) and results in loss of cognitive function. One of the causative agents for the synaptic degeneration is the amyloid β-peptide (Aβ), which is formed from its precursor
Autor:
Schedin-Weiss, Sophia, Mitsuhiro Inoue, Hromadkova, Lenka, Yasuhiro Teranishi, Natsuko Goto Yamamoto, Wiehager, Birgitta, Bogdanovic, Nenad, Winblad, Bengt, Sandebring-Matton, Anna, Frykman, Susanne, Tjernberg, Lars O.
Publikováno v:
Alzheimer's Research & Therapy; 8/1/2017, Vol. 9, p1-19, 19p