Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Natsue Igarashi"'
Autor:
Koichiro Nozaki, Hiroshi Kagamu, Satoshi Shoji, Natsue Igarashi, Aya Ohtsubo, Masaaki Okajima, Satoru Miura, Satoshi Watanabe, Hirohisa Yoshizawa, Ichiei Narita
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111019 (2014)
The specific mechanisms how lung cancer cells harboring epidermal growth factor receptor (EGFR) activating mutations can survive treatment with EGFR-tyrosine kinase inhibitors (TKIs) until they eventually acquire treatment-resistance genetic mutation
Externí odkaz:
https://doaj.org/article/87dfd960fcf84ef4ab3013f6e486d111
Autor:
Natsue Igarashi, Junko Baba, Toshiyuki Koya, Junta Tanaka, Satoshi Shoji, Masaaki Okajima, Koh Nakata, Rie Kondo, Koichiro Nozaki, Jun Koshio, Hiroshi Kagamu, Satoru Miura, Kosuke Ichikawa, Satoshi Watanabe, Ko Sato, Daisuke Ishikawa, Yu Saida, Tomohiro Tanaka, Hirohisa Yoshizawa, Ichiei Narita
Publikováno v:
The Journal of Immunology. 195:726-735
Antitumor immunity is augmented by cytotoxic lymphodepletion therapies. Adoptively transferred naive and effector T cells proliferate extensively and show enhanced antitumor effects in lymphopenic recipients. Although the impact of lymphodepletion on
Autor:
Natsue Igarashi, Satoshi Shoji, Satoru Miura, Satoshi Watanabe, Koichiro Nozaki, Ichiei Narita, Tomohiro Tanaka, Jun Koshio, Masaaki Okajima, Yu Saida, Hirohisa Yoshizawa, Hiroshi Kagamu
Publikováno v:
Cancer Immunology, Immunotherapy. 62:1619-1628
Accumulating evidence suggests that most solid malignancies consist of heterogeneous tumor cells and that a relatively small subpopulation, which shares biological features with stem cells, survives through potentially lethal stresses such as chemoth
Publikováno v:
Journal of Clinical and Experimental Hematopathology. 53:63-68
We report five cases that presented with high fever, anasarca, hepatosplenomegaly and severe thrombocytopenia with reticulin fibrosis of the bone marrow. The constellation of symptoms is not compatible with any known disease, and we had difficulty in
Autor:
Takuro Ishiguro, Takayuki Hirose, Haruki Nagai, Fumiko Kawahara, Yoshimi Tanaka, Masaki Yoshino, Yosuke Imai, Takaaki Chou, Mayumi Kaise, Natsue Igarashi
Publikováno v:
Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 38:664-671
Publikováno v:
International Journal of Hematology. 92:518-523
Bortezomib is a novel proteasome inhibitor, which has shown high antimyeloma activity. APEX trial, phase III randomized study for relapsed or refractory myeloma established efficacy and feasibility of bortezomib. In our study, we retrospectively inve
Autor:
Satoshi Shoji, Natsue Igarashi, Aya Ohtsubo, Hirohisa Yoshizawa, Ichiei Narita, Satoshi Watanabe, Koichiro Nozaki, Hiroshi Kagamu, Satoru Miura, Masaaki Okajima
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 10, p e111019 (2014)
PLoS ONE, Vol 9, Iss 10, p e111019 (2014)
The specific mechanisms how lung cancer cells harboring epidermal growth factor receptor (EGFR) activating mutations can survive treatment with EGFR-tyrosine kinase inhibitors (TKIs) until they eventually acquire treatment-resistance genetic mutation
Autor:
Masachika, Hayashi, Natsue, Igarashi, Fumio, Fujimori, Hideyuki, Kuriyama, Yusuke, Ebe, Takeaki, Nishibori, Kazuhiro, Sato, Yasuko, Hosaka, Yasushi, Yamato, Kenichi, Togashi, Toshio, Yano
Publikováno v:
Gan to kagaku ryoho. Cancerchemotherapy. 41(7)
We report a case of a 38-year-old man who was diagnosed with a mediastinal germ cell tumor. After induction chemotherapy, the tumor marker levels normalized, but the tumor itself continued to grow. Surgical resection was performed successfully, but t
Autor:
Keiichi Nemoto, Natsue Igarashi, Takuro Ishiguro, Takayuki Hirose, Takaaki Chou, Yousuke Imai
Publikováno v:
International journal of hematology. 90(3)
Donor cell leukemia (DCL) is a rare, but well-known, complication after allogeneic hematopoietic cell transplantation. We report a case of donor cell-derived acute lymphocytic leukemia (ALL) occurring in a 55-year-old man after allogeneic bone marrow
Autor:
Hrohisa Yoshizawa, Natsue Igarashi, Koichiro Nozaki, Satoshi Shoji, Masaaki Okajima, Ichiei Narita, Satoshi Watanabe, Hiroshi Kagamu, Satoru Miura
Publikováno v:
Cancer Research. 74:200-200
[Background] The treatment targeting signal addiction caused by oncogenic driver mutation has led to unprecedented results in clinical setting; however, it is still difficult to achieve cure. Tumor diversity based on both genetic and non-genetic infl