A mouse SWATH-mass spectrometry reference spectral library enables deconvolution of species-specific proteomic alterations in human tumour xenografts.

Autor: Krasny L; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Bland P; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Burns J; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Lima NC; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Harrison PT; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Pacini L; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Elms ML; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK., Ning J; Tumour Profiling Unit, The Institute of Cancer Research, London SW3 6JB, UK., Martinez VG; Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London WC1E 6BT, London, UK., Yu YR; Department of Oncology, University of Lausanne, Lausanne CH-1066, Switzerland.; Ludwig Institute for Cancer Research, Lausanne CH-1066, Switzerland., Acton SE; Stromal Immunology Group, MRC Laboratory for Molecular Cell Biology, University College London WC1E 6BT, London, UK., Ho PC; Department of Oncology, University of Lausanne, Lausanne CH-1066, Switzerland.; Ludwig Institute for Cancer Research, Lausanne CH-1066, Switzerland., Calvo F; The Tumour Microenvironment Team, Institute of Biomedicine and Biotechnology of Cantabria, Santander 39011, Spain., Swain A; Tumour Profiling Unit, The Institute of Cancer Research, London SW3 6JB, UK., Howard BA; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Natrajan RC; The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London SW3 6JB, UK., Huang PH; Division of Molecular Pathology, The Institute of Cancer Research, London SW3 6JB, UK paul.huang@icr.ac.uk.

Publikováno v: Disease models & mechanisms [Dis Model Mech] 2020 Jul 14; Vol. 13 (7). Date of Electronic Publication: 2020 Jul 14.

SWATH mass spectrometry as a tool for quantitative profiling of the matrisome.

Autor: Krasny L; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK., Bland P; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, SW3 6JB, UK., Kogata N; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, SW3 6JB, UK., Wai P; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, SW3 6JB, UK., Howard BA; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, SW3 6JB, UK., Natrajan RC; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, SW3 6JB, UK., Huang PH; Division of Molecular Pathology, The Institute of Cancer Research, London, SW3 6JB, UK. Electronic address: paul.huang@icr.ac.uk.

Publikováno v: Journal of proteomics [J Proteomics] 2018 Oct 30; Vol. 189, pp. 11-22. Date of Electronic Publication: 2018 Mar 01.

Proteomic analysis of decellularized mice liver and kidney extracellular matrices.

Autor: Diedrich, Anna-Maria¹ (AUTHOR), Daneshgar, Assal^2,3 (AUTHOR), Tang, Peter² (AUTHOR), Klein, Oliver⁴ (AUTHOR), Mohr, Annika¹ (AUTHOR), Onwuegbuchulam, Olachi A.¹ (AUTHOR), von Rueden, Sabine¹ (AUTHOR), Menck, Kerstin^5,6 (AUTHOR), Bleckmann, Annalen^5,6 (AUTHOR), Juratli, Mazen A.^1,6 (AUTHOR), Becker, Felix^1,6 (AUTHOR), Sauer, Igor M.² (AUTHOR), Hillebrandt, Karl H.^2,3 (AUTHOR), Pascher, Andreas^1,6 (AUTHOR), Struecker, Benjamin^1,6 (AUTHOR) benjamin.struecker@ukmuenster.de

Publikováno v: Journal of Biological Engineering. 2/22/2024, Vol. 18 Issue 1, p1-16. 16p.

Dual Targeting of PDGFRα and FGFR1 Displays Synergistic Efficacy in Malignant Rhabdoid Tumors.

Autor: Wong JP; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Todd JR; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Finetti MA; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE1 4LP, UK., McCarthy F; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Broncel M; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Vyse S; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Luczynski MT; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Crosier S; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE1 4LP, UK., Ryall KA; Translational Bioinformatics and Cancer Systems Biology Laboratory, Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Holmes K; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Payne LS; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK., Daley F; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK., Wai P; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK., Jenks A; Division of Cancer Therapeutics, The Institute of Cancer Research, London SW3 6JB, UK., Tanos B; Division of Cancer Therapeutics, The Institute of Cancer Research, London SW3 6JB, UK., Tan AC; Translational Bioinformatics and Cancer Systems Biology Laboratory, Division of Medical Oncology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA., Natrajan RC; The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London SW3 6JB, UK., Williamson D; Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE1 4LP, UK., Huang PH; Division of Cancer Biology, The Institute of Cancer Research, London SW3 6JB, UK. Electronic address: paul.huang@icr.ac.uk.

Publikováno v: Cell reports [Cell Rep] 2016 Oct 25; Vol. 17 (5), pp. 1265-1275.

Breast cancer heterogeneity: parallel evolution or conscious uncoupling?

Autor: Natrajan RC; Breakthrough Breast Cancer Research Centre and Department of Molecular Pathology, Institute of Cancer Research, London, UK.

Publikováno v: The Journal of pathology [J Pathol] 2015 Sep; Vol. 237 (1), pp. 1-3. Date of Electronic Publication: 2015 May 28.