Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Natia Q. Kelm"'
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 5, Pp 304-314 (2020)
Abstract Background Ischemia reperfusion (IR) injury leads to activation of dynamin‐related protein (Drp‐1), causing mitochondrial fission and generation of reactive oxygen species (ROS), but the molecular mechanisms that activate Drp‐1 are not
Externí odkaz:
https://doaj.org/article/2b74ed5e86194658b1798631f2de197f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cachexia is a complex wasting syndrome that overwhelmingly affects the majority of late-stage cancer patients. Additionally, there are currently no efficacious therapeutic agents to treat the muscle atrophy induced by the cancer. While several precli
Externí odkaz:
https://doaj.org/article/21ebd1ac5a7e48d387c9168ecf42df51
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236680 (2020)
Cachexia is a common multifactorial syndrome in the advanced stages of cancer and accounts for approximately 20-30% of all cancer-related fatalities. In addition to the progressive loss of skeletal muscle mass, cancer results in impairments in cardia
Externí odkaz:
https://doaj.org/article/adeddbbfbbf4481c87beb41687c33cff
Autor:
Natia Q Kelm, Jason E Beare, Fangping Yuan, Monika George, Charles M Shofner, Bradley B Keller, James B Hoying, Amanda J LeBlanc
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202934 (2018)
An early manifestation of coronary artery disease in advanced age is the development of microvascular dysfunction leading to deficits in diastolic function. Our lab has previously shown that epicardial treatment with adipose-derived stromal vascular
Externí odkaz:
https://doaj.org/article/609b4a4e2dd04dfb9027cdcd489981da
Publikováno v:
FASEB BioAdvances
FASEB BioAdvances, Vol 2, Iss 5, Pp 304-314 (2020)
FASEB BioAdvances, Vol 2, Iss 5, Pp 304-314 (2020)
Background Ischemia reperfusion (IR) injury leads to activation of dynamin‐related protein (Drp‐1), causing mitochondrial fission and generation of reactive oxygen species (ROS), but the molecular mechanisms that activate Drp‐1 are not known. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c1b59aea47936b3ff73ca1af38806c
http://europepmc.org/articles/PMC7211039
http://europepmc.org/articles/PMC7211039
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236680 (2020)
PLoS ONE
PLoS ONE
Cachexia is a common multifactorial syndrome in the advanced stages of cancer and accounts for approximately 20–30% of all cancer-related fatalities. In addition to the progressive loss of skeletal muscle mass, cancer results in impairments in card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181a87e8269a052b67411c807fa30be7
https://doaj.org/article/adeddbbfbbf4481c87beb41687c33cff
https://doaj.org/article/adeddbbfbbf4481c87beb41687c33cff
Publikováno v:
Current Opinion in Physiology. 1:27-33
Advancing age will affect every individual and its impact on cardiac health deserves significant attention. The age-related physiological changes occurring in the coronary vasculature, myocardium, and valves set the stage upon which cardiovascular di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc303c9aa9b6ed48fe4adf689920624
https://doi.org/10.1016/j.cophys.2017.07.001
https://doi.org/10.1016/j.cophys.2017.07.001
Publikováno v:
Cancer Research. 80:439-439
The purpose of this study was to investigate whether cardiac cachexia occurs in the context of ovarian cancer and whether Withaferin A could ameliorate the cachectic phenotype. We believe that treatment with Withaferin A can ameliorate cancer-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c96053f81789fdd6d4e29ea641c257e1
https://doi.org/10.1158/1538-7445.am2020-439
https://doi.org/10.1158/1538-7445.am2020-439
Publikováno v:
Journal of visualized experiments : JoVE. (148)
Coronary artery disease is the leading cause of death worldwide. After an acute myocardial infarction, early and successful myocardial intervention via recanalization of the coronary artery is the most effective strategy for reducing the size of isch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad8c43caa31142c571a547759ac8ee3f
https://pubmed.ncbi.nlm.nih.gov/31305512
https://pubmed.ncbi.nlm.nih.gov/31305512
Publikováno v:
Aging (Albany NY)
Our past study showed that a single tail vein injection of adipose-derived stromal vascular fraction (SVF) into old rats was associated with improved dobutamine-mediated coronary flow reserve. We hypothesize that i.v. injection of SVF improves corona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595cba008a81dbb0ad4c4d8a849a5997
https://pubmed.ncbi.nlm.nih.gov/31296794
https://pubmed.ncbi.nlm.nih.gov/31296794