Utility of protein-protein binding surfaces composed of anti-parallel alpha-helices and beta-sheets selected by phage display.

Autor: Zhu N; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Smallwood PM; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Rattner A; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Chang TH; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Williams J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Wang Y; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA., Nathans J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, USA; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, USA; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, USA. Electronic address: jnathans@jhmi.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2024 May; Vol. 300 (5), pp. 107283. Date of Electronic Publication: 2024 Apr 11.

Seeing is believing: The development of optical coherence tomography.

Autor: Nathans J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Sep 26; Vol. 120 (39), pp. e2311129120. Date of Electronic Publication: 2023 Sep 21.

Bacterial meningitis in the early postnatal mouse studied at single-cell resolution.

Autor: Wang J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, United States., Rattner A; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States., Nathans J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, United States.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, United States.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, United States.

Publikováno v: ELife [Elife] 2023 Jun 15; Vol. 12. Date of Electronic Publication: 2023 Jun 15.

Structural insights into plasmalemma vesicle-associated protein (PLVAP): Implications for vascular endothelial diaphragms and fenestrae.

Autor: Chang TH; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Hsieh FL; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Gu X; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Smallwood PM; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Kavran JM; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205., Gabelli SB; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205., Nathans J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; HHMI, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205.; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Apr 04; Vol. 120 (14), pp. e2221103120. Date of Electronic Publication: 2023 Mar 30.

The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development.

Autor: Wang Y; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Venkatesh A; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Xu J; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Xu M; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Williams J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Smallwood PM; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., James A; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Nathans J; Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Howard Hughes Medical Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

Publikováno v: Development (Cambridge, England) [Development] 2022 May 01; Vol. 149 (9). Date of Electronic Publication: 2022 May 12.