Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Nathaniel Weygant"'
Autor:
Janani Panneerselvam, Priyanga Mohandoss, Ravi Patel, Hamza Gillan, Michael Li, Kirtana Kumar, DangHuy Nguyen, Nathaniel Weygant, Dongfeng Qu, Kamille Pitts, Stanley Lightfoot, Chinthalapally Rao, Courtney Houchen, Michael Bronze, Parthasarathy Chandrakesan
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 24-36 (2020)
Chemoresistance cells have features similar to cancer stem cells. Elimination of these cells is an effective therapeutic strategy to clinically combat chemoresistance non-small cell lung cancer (NSCLC). Here, we demonstrate that Doublecortin-like kin
Externí odkaz:
https://doaj.org/article/06ca05c4186b44ef85df781d0e227141
Autor:
Ziwei Liang MD, Enyu Zhang MD, Ling Duan MD, Nathaniel Weygant PhD, Guangyu An MD, PhD, Bin Hu MD, PhD, Jiannan Yao MD, PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Background and aim: Pulmonary sarcomatoid carcinoma (PSC) is a rare subtype of nonsmall cell lung cancer with a poor prognosis. This study aimed to analyze the clinicopathological characteristics and survival outcomes among patients with PSC, lung sq
Externí odkaz:
https://doaj.org/article/79a60342b00343b6b929b27985ac6e88
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: As immune checkpoint inhibitors (ICIs) transition to the forefront of cancer treatment, a better understanding of immune related adverse events (IRAEs) is essential to promote safe clinical practice. Dermatologic adverse events are the mo
Externí odkaz:
https://doaj.org/article/eec106773e454ce186a87db0a90451db
Autor:
Emily M. Christman, Parthasarathy Chandrakesan, Nathaniel Weygant, John T. Maple, William M. Tierney, Kenneth J. Vega, Courtney W. Houchen
Publikováno v:
Biomarker Research, Vol 7, Iss 1, Pp 1-5 (2019)
Abstract Background Barrett’s esophagus (BE) and esophageal adenocarcinoma (EAC) incidence has been increasing in the United States for greater than 30 years. For the majority of EAC patients, treatment is limited and prognosis poor. Doublecortin l
Externí odkaz:
https://doaj.org/article/b5557fca45764624b93dfe0f98caa7ff
Autor:
Zhiqing Shen, Aling Shen, Xiaoping Chen, Xiangyan Wu, Jianfeng Chu, Ying Cheng, Meizhong Peng, Youqin Chen, Nathaniel Weygant, Meizhu Wu, Xiaoying Lin, Jun Peng, Keji Chen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 130, Iss , Pp 110618- (2020)
Huoxin Pill (HXP), a Traditional Chinese Medicine, is used widely to treat patients with coronary heart disease and angina pectoris in China. However, the underlying protective mechanism of HXP on cardiac apoptosis and fibrosis has never been evaluat
Externí odkaz:
https://doaj.org/article/7d7037a4a09f434581137d259ca1ef5d
Autor:
Jiannan Yao, Wanchun Zang, Yang Ge, Nathaniel Weygant, Pan Yu, Lei Li, Guanhua Rao, Zhi Jiang, Rui Yan, Linjia He, Yang Yu, Mulan Jin, Gang Cheng, Guangyu An
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2018 (2018)
Background. Since circulating tumor DNA (ctDNA) offers clear advantages as a minimally invasive method for tumor monitoring compared with tumor tissue, we aimed to evaluate genotyping ctDNA using a next-generation sequencing- (NGS-) based panel to id
Externí odkaz:
https://doaj.org/article/acf44ed458004276abdd28f7293445a1
Autor:
Dongfeng Qu, Jeremy Johnson, Parthasarathy Chandrakesan, Nathaniel Weygant, Randal May, Nicole Aiello, Andrew Rhim, Lichao Zhao, Wei Zheng, Stanley Lightfoot, Shubham Pant, Jeremy Irvan, Russell Postier, James Hocker, Jay S Hanas, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Ben Stanger, Courtney W Houchen
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0118933 (2015)
Doublecortin-like kinase 1 (DCLK1) is a putative pancreatic stem cell marker and is upregulated in pancreatic cancer, colorectal cancer, and many other solid tumors. It marks tumor stem cells in mouse models of intestinal neoplasia. Here we sought to
Externí odkaz:
https://doaj.org/article/f252e7d7a9a5466fb4e873020e5443fe
Autor:
Sripathi M Sureban, Randal May, Dongfeng Qu, Parthasarathy Chandrakesan, Nathaniel Weygant, Naushad Ali, Stan A Lightfoot, Kai Ding, Shahid Umar, Michael J Schlosser, Courtney W Houchen
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0135561 (2015)
Gastrointestinal (GI) mucosal damage is a devastating adverse effect of radiation therapy. We have recently reported that expression of Dclk1, a Tuft cell and tumor stem cell (TSC) marker, 24h after high dose total-body gamma-IR (TBI) can be used as
Externí odkaz:
https://doaj.org/article/7b97145731fd4fc48d263fefd5ebb81a
Autor:
Dongfeng Qu, Nathaniel Weygant, Randal May, Parthasarathy Chandrakesan, Mohammad Madhoun, Naushad Ali, Sripathi M Sureban, Guangyu An, Michael J Schlosser, Courtney W Houchen
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134212 (2015)
Doublecortin-like kinase 1 (Dclk1), a microtubule-associated kinase, marks the fifth lineage of intestinal epithelial cells called tuft cells that function as tumor stem cells in Apc mutant models of colon cancer. In order to determine the role of Dc
Externí odkaz:
https://doaj.org/article/359c4b5cd96646438ca15e2acc234dbc
Autor:
Naushad Ali, Heba Allam, Ted Bader, Randal May, Kanthesh M Basalingappa, William L Berry, Parthasarathy Chandrakesan, Dongfeng Qu, Nathaniel Weygant, Michael S Bronze, Shahid Umar, Ralf Janknecht, Sripathi M Sureban, Mark Huycke, Courtney W Houchen
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80304 (2013)
Hepatitis C virus (HCV)-induced alterations in lipid metabolism and cellular protein expression contribute to viral pathogenesis. The mechanism of pleiotropic actions of cholesterol-lowering drugs, statins, against HCV and multiple cancers are not we
Externí odkaz:
https://doaj.org/article/3577621465fa40e3ad4a93f14a04b76d