Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nathaniel W. Holton"'
Autor:
Seema Saksena, Christopher R. Manzella, Anoop Kumar, David Jarava, Alexander L. Ticho, Waddah A. Alrefai, Ravinder K. Gill, Pooja Malhotra, Pradeep K. Dudeja, Megha Singhal, Nathaniel W Holton
Publikováno v:
Am J Physiol Cell Physiol
The serotonin transporter (SERT) functions to regulate the availability of serotonin (5-HT) in the brain and intestine. An intestine-specific mRNA variant arising from a unique transcription start site and alternative promoter in the SERT gene has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca71f9737abe75bd89cef50741840b3
https://doi.org/10.1152/ajpcell.00477.2019
https://doi.org/10.1152/ajpcell.00477.2019
Autor:
James E Prusak, Meghan A Dean, Donavon J Dahmer, Michael E Zambrano, Brianna C Watters, Jeffrey D Demeis, Aline Crucello, Jaire A. Ferreira-Filho, Nathaniel W. Holton, Zara Ijaz, Glen M. Borchert, Valeria M. King, Addison A Barchie, Emmaline C Barnhill, Justin T Roberts, Michael P. Spector, Shivam V Amin, Dominika Houserova, Anderson S. Sant'Ana
Publikováno v:
RNA Biology. 16:1643-1657
Noncoding RNA (ncRNA) modulation of gene expression has now been ubiquitously observed across all domains of life. An increasingly apparent role of ncRNAs is to coordinate changes in gene expressions in response to environmental stress. Salmonella en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fff3fb46e4dd20f5a3ca5c5de1ed23ae
https://doi.org/10.1080/15476286.2019.1653680
https://doi.org/10.1080/15476286.2019.1653680
Autor:
Pradeep K. Dudeja, Aisha Qazi, Anchal Sharma, Waddah A. Alrefai, Nathan Calzadilla, Christopher R. Weber, Pooja Malholtra, Ravinder K. Gill, Nathaniel W Holton, Kai Mongan, Jeet Bhalala, Velavan Bakthavachalam, Seema Saksena, Anoop Kumar, Sofia Ahmed
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7d2e7128299e09144388c0d54c08b88
https://doi.org/10.1096/fasebj.2021.35.s1.03369
https://doi.org/10.1096/fasebj.2021.35.s1.03369
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11641 (2010)
Somatic hypermutation introduces base substitutions into the rearranged and expressed immunoglobulin (Ig) variable regions to promote immunity. This pathway requires and is initiated by the Activation Induced Deaminase (AID) protein, which deaminates
Externí odkaz:
https://doaj.org/article/d2c9cbad8afc4ac1a876c16802966ec2
Autor:
Emmaline C, Barnhill, Aline, Crucello, Dominika, Houserova, Valeria M, King, Shivam V, Amin, Justin T, Roberts, Michael E, Zambrano, Jeffrey D, DeMeis, Donavon J, Dahmer, Zara, Ijaz, Addison A, Barchie, Brianna C, Watters, James E, Prusak, Meghan A, Dean, Nathaniel W, Holton, Jaire A, Ferreira-Filho, Anderson S, Sant'Ana, Michael P, Spector, Glen M, Borchert
Publikováno v:
RNA Biol
Noncoding RNA (ncRNA) modulation of gene expression has now been ubiquitously observed across all domains of life. An increasingly apparent role of ncRNAs is to coordinate changes in gene expressions in response to environmental stress. Salmonella en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e1d94b6dae379d4b624773b3d34e5fa
https://pubmed.ncbi.nlm.nih.gov/31390935
https://pubmed.ncbi.nlm.nih.gov/31390935
Autor:
Natalie R. Gassman, Nathaniel W Holton
Publikováno v:
Current opinion in biotechnology. 55
Detection and characterization of DNA damage is essential for evaluating genotoxicity, monitoring DNA repair, developing biomarkers for exposures, and evaluating the efficacy of chemotherapies. These diverse applications for DNA damage measurements h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097798e996711a6306a99affe9a88f2b
https://pubmed.ncbi.nlm.nih.gov/30114673
https://pubmed.ncbi.nlm.nih.gov/30114673
Publikováno v:
DNA Repair
Environmental exposures, reactive by-products of cellular metabolism, and spontaneous deamination events result in a spectrum of DNA adducts that if un-repaired threaten genomic integrity by inducing mutations, increasing instability, and contributin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::184b9c735a7f6a846ccf2ff2ea4aa8f3
Publikováno v:
Journal of Visualized Experiments : JoVE
Highly coordinated DNA repair pathways exist to detect, excise and replace damaged DNA bases, and coordinate repair of DNA strand breaks. While molecular biology techniques have clarified structure, enzymatic functions, and kinetics of repair protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55aa4333fa6d2211c99c4d3b557efa4e
https://doi.org/10.3791/56265-v
https://doi.org/10.3791/56265-v
Autor:
Jonathan D. Williams, Joe C. Lengerich, Nathaniel S. Gregoire, Ian P. Bishop, Arianna A. Medema, Marilyn A. Nguyen, Darren J. Wozniak, Glen M. Borchert, Nicholas J. Tardi, Joel A. Dembosky, Jee-Ah Kim, Wesley W. Koehler, Michelle A. Rarick, Geoffrey D. Ower, Nathan M. Tasker, Craig Gatto, William L. Hernan, Nathaniel W. Holton, Brooke N. Strong, James E. Elste, Erik D. Larson
Publikováno v:
Mobile Genetic Elements. 1:8-17
MicroRNAs (miRs) are small non-coding RNAs that generally function as negative regulators of target messenger RNAs (mRNAs) at the posttranscriptional level. MiRs bind to the 3′UTR of target mRNAs through complementary base pairing, resulting in tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefaebc8aaca7abeec9514bd50105d4f
https://doi.org/10.4161/mge.1.1.15766
https://doi.org/10.4161/mge.1.1.15766
Publikováno v:
BMC Cancer
BMC Cancer, Vol 11, Iss 1, p 347 (2011)
BMC Cancer, Vol 11, Iss 1, p 347 (2011)
Background Activation Induced cytidine Deaminase (AID) targets the immunoglobulin genes of activated B cells, where it converts cytidine to uracil to induce mutagenesis and recombination. While essential for immunoglobulin gene diversification, AID m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa1522e21d10c736b970c379ace7f7b
https://pubmed.ncbi.nlm.nih.gov/21831295
https://pubmed.ncbi.nlm.nih.gov/21831295