Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nathaniel Talledge"'
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Studies of retroviruses have led to many extraordinary discoveries that have advanced our understanding of not only human diseases, but also molecular biology as a whole. The most recognizable human retrovirus, human immunodeficiency virus type 1 (HI
Externí odkaz:
https://doaj.org/article/ee020635a5924816b64ce4e4e0ef7019
Autor:
Joachim Moser von Filseck, Luca Barberi, Nathaniel Talledge, Isabel E. Johnson, Adam Frost, Martin Lenz, Aurélien Roux
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here, the authors use cryo-ET, cryo-EM and mathematical modeling to reveal how the shape of the helical membrane tube arises from the assembly of
Externí odkaz:
https://doaj.org/article/ffbbce3ca19e4ccbb4dd18d0ff5b656f
Autor:
Annika Hohendahl, Nathaniel Talledge, Valentina Galli, Peter S Shen, Frédéric Humbert, Pietro De Camilli, Adam Frost, Aurélien Roux
Publikováno v:
eLife, Vol 6 (2017)
Dynamin, which mediates membrane fission during endocytosis, binds endophilin and other members of the Bin-Amphiphysin-Rvs (BAR) protein family. How endophilin influences endocytic membrane fission is still unclear. Here, we show that dynamin-mediate
Externí odkaz:
https://doaj.org/article/1f58939bb40244c692ce93916cfa6d64
HIV-2 Immature Particle Morphology Provides Insights into Gag Lattice Stability and Virus Maturation
Autor:
Nathaniel Talledge, Huixin Yang, Ke Shi, Raffaele Coray, Guichuan Yu, William G. Arndt, Shuyu Meng, Gloria C. Baxter, Luiza M. Mendonça, Daniel Castaño-Díez, Hideki Aihara, Louis M. Mansky, Wei Zhang
Publikováno v:
Journal of Molecular Biology. 435:168143
Retrovirus immature particle morphology consists of a membrane enclosed, pleomorphic, spherical and incomplete lattice of Gag hexamers. Previously, we demonstrated that human immunodeficiency virus type 2 (HIV-2) immature particles possess a distinct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb95be03f1d1fe8d891293370af43d
https://doi.org/10.1016/j.jmb.2023.168143
https://doi.org/10.1016/j.jmb.2023.168143
Human immunodeficiency virus (HIV) Gag drives virus particle assembly. The capsid (CA) domain is critical for Gag multimerization mediated by protein-protein interactions. The Gag protein interaction network defines critical aspects of the retroviral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221411b1510a1d8470302e37fe1ec944
https://doi.org/10.1101/2022.01.31.478542
https://doi.org/10.1101/2022.01.31.478542
Autor:
Steven E. Patterson, Louis M. Mansky, Yumeng Z McDaniel, Michele B. Daly, Willie M. Greggs, Megan E. Roth, Nathaniel Talledge, Baek Kim
Publikováno v:
J Mol Biol
5-aza-cytidine (5-aza-C) has been shown to be a potent human immunodeficiency virus type 1 (HIV-1) mutagen that induces G-to-C hypermutagenesis by incorporation of the reduced form (i.e., 5-aza-dC, 5-aza-dCTP). Evidence to date suggests that this let
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7817eed5d5034a00e0262fa8423c3c27
https://europepmc.org/articles/PMC8380735/
https://europepmc.org/articles/PMC8380735/
Autor:
Mina Henes, Celia A. Schiffer, Nese Kurt Yilmaz, Mohan Somasundaran, Gordon J. Lockbaum, Linah N. Rusere, Akbar Ali, Ellen A. Nalivaika, Klajdi Kosovrasti, Louis M. Mansky, Nathaniel Talledge
Publikováno v:
ACS Chem Biol
Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that can cause severe paralytic neurologic disease and immune disorders as well as cancer. An estimated 20 million people worldwide are infected with HTLV-1, with prevalence reaching 30%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ef76a256b99966f051bbbb9aa17023
https://pubmed.ncbi.nlm.nih.gov/33619959
https://pubmed.ncbi.nlm.nih.gov/33619959
Autor:
Louis M. Mansky, Miranda Harris, Sneha Ratnapriya, Angela Chov, Alisha Block, Joseph Sodroski, Alon Herschhorn, Héctor Cervera, Nathaniel Talledge, Christopher Gu
Publikováno v:
Cell Rep
Summary Many HIV strains downregulate the levels of CD4 receptor on the surface of infected cells to prevent superinfection. In contrast, the rare HIV-2UC1 strain is noncytopathic and has no effect on CD4 expression in infected cells but still replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb4231ac91a7931a64b05e74576d442
https://europepmc.org/articles/PMC7336836/
https://europepmc.org/articles/PMC7336836/
Autor:
Adam Frost, Nathaniel Talledge, Joachim Moser von Filseck, Aurélien Roux, Luca Barberi, Martin Lenz, Isabel E. Johnson
Publikováno v:
Nature communications, vol 11, iss 1
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-15327-4⟩
Nature Communications, Vol. 11, No 1516 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-15327-4⟩
Nature Communications, Vol. 11, No 1516 (2020)
ESCRT-III proteins assemble into ubiquitous membrane-remodeling polymers during many cellular processes. Here we describe the structure of helical membrane tubes that are scaffolded by bundled ESCRT-III filaments. Cryo-ET reveals how the shape of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1403d43d16253588598c5f31c96bc1a5
https://escholarship.org/uc/item/081603m4
https://escholarship.org/uc/item/081603m4
Autor:
Nathaniel Talledge, John McCullough, Wesley I. Sundquist, Henry C. Nguyen, Abhimanyu Sharma, Janet Iwasa, Frank R. Moss, Michael Vershinin, Adam Frost
Publikováno v:
Nature structural & molecular biology, vol 27, iss 4
The Endosomal Sorting Complexes Required for Transport (ESCRTs) mediate diverse membrane remodeling events. These activities typically require ESCRT-III proteins to stabilize negatively-curved membranes, although recent work has indicated that certai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911cd6a5336bb7b6809dc569098ac140
https://escholarship.org/uc/item/5gg326gr
https://escholarship.org/uc/item/5gg326gr