Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models

Autor: Joseph I. Shapiro, Rebecca Pratt, Richard B. Miller, Scott Thiesfeldt, Nathaniel Seth Adkins, David E. Bartlett, D. Blaine Nease, Hari Vishal Lakhani, Rebecca L. Klug, Cameron L. Cottrill, Paul Bown, Tilak Khanal, Komal Sodhi

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2685 (2018)
Volume 19
Issue 9

Background: Oxidant stress plays a key role in the development of chronic kidney disease (CKD). Experimental CKD leads to accumulation of uremic toxins (UT) in the circulation resulting in increased ROS production, which in turn, is known to activate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f860cc3b74c008b18b9bd51b032a505
http://europepmc.org/articles/PMC6164729