Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Nathaniel Robichaud"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/2536b972e77c4d0fa4f0579691c1d2cc
Autor:
Chadi Zakaria, Polen Sean, Huy-Dung Hoang, Louis-Phillipe Leroux, Margaret Watson, Samuel Tekeste Workenhe, Jaclyn Hearnden, Dana Pearl, Vinh Tai Truong, Nathaniel Robichaud, Akiko Yanagiya, Soroush Tahmasebi, Seyed Mehdi Jafarnejad, Jian-Jun Jia, Adrian Pelin, Jean-Simon Diallo, Fabrice Le Boeuf, John Cameron Bell, Karen Louise Mossman, Tyson Ernst Graber, Maritza Jaramillo, Nahum Sonenberg, Tommy Alain
Publikováno v:
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)
Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within tumours is limiting. Rapamycin can stimulate HSV1 replication in cancer cells, but active-site
Externí odkaz:
https://doaj.org/article/513a554b6c4d453d9e82ff6357c01efc
Autor:
Alba Martínez, Marta Sesé, Javier Hernandez Losa, Nathaniel Robichaud, Nahum Sonenberg, Trond Aasen, Santiago Ramón Y Cajal
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123352 (2015)
Phosphorylation of the eukaryotic translation initiation factor eIF4E is associated with malignant progression and poor cancer prognosis. Accordingly, here we have analyzed the association between eIF4E phosphorylation and cellular resistance to oxid
Externí odkaz:
https://doaj.org/article/249404e0ebb1406ba3ad777b63fa4a1f
Autor:
Milad Dagher, Grant Ongo, Nathaniel Robichaud, Jinglin Kong, Woojong Rho, Ivan Teahulos, Arya Tavakoli, Samantha Bovaird, Shahem Merjaneh, Andrew Tan, Kiran Edwardson, Christelle Scheepers, Andy Ng, Andy Hajjar, Andy Lee, Philippe DeCorwin-Martin, Shafqat Rasool, JiaMin Huang, Yu Han, Srinivas Niranj Chandrasekaran, Lisa Miller, Maria Kost-Alimova, Adam Skepner, Shantanu Singh, Jeffrey Munzar, Anne E. Carpenter, David Juncker
Publikováno v:
bioRxiv
We present the nELISA, a miniaturised, high-throughput, and high-fidelity protein profiling platform. DNA oligonucleotides are used to pre-colocalize antibody pairs on spectrally encoded microparticles and perform displacement-mediated detection whil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c94a171a9e17b6c6ab9becdfccca9a
https://europepmc.org/articles/PMC10153206/
https://europepmc.org/articles/PMC10153206/
Autor:
Sakie Katsumura, Nahum Sonenberg, Sang-Ging Ong, Soroush Tahmasebi, Sung-Hoon Kim, Nathaniel Robichaud, Hamza Ali, Xu Zhang, Dana Pearl, Xinhe Pang, Mehdi Amiri, Jian Jun Jia, Maritza Jaramillo, Shawn Beug, Michel L. Tremblay, Negar Tabatabaei, Valerie Vinette, Laura M. Jones, Masahiro Morita, Tommy Alain
Publikováno v:
The Journal of Immunology. 204:2392-2400
Deregulation of mRNA translation engenders many human disorders, including obesity, neurodegenerative diseases, and cancer, and is associated with pathogen infections. The role of eIF4E-dependent translational control in macrophage inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70c2b9eae13b0f6017a85cd69d0872c0
https://doi.org/10.4049/jimmunol.1900538
https://doi.org/10.4049/jimmunol.1900538
Autor:
Rongtuan Lin, Angela P. Hackett, Sung-Hoon Kim, David L. Dai, Tommy Alain, Seyed Mehdi Jafarnejad, Isabela Fabri Karam, Nahum Sonenberg, Long Yang, Clément Chapat, Jung-Hyun Choi, Shane Wiebe, Jun Luo, Nathaniel Robichaud, Qian Li, Peng Wang, Xu Zhang
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2021, 81 (6), pp.1187-1199.e5. ⟨10.1016/j.molcel.2021.01.030⟩
Molecular Cell, Elsevier, 2021, 81 (6), pp.1187-1199.e5. ⟨10.1016/j.molcel.2021.01.030⟩
Summary Type I interferons (IFNs) are critical cytokines in the host defense against invading pathogens. Sustained production of IFNs, however, is detrimental to the host, as it provokes autoimmune diseases. Thus, the expression of IFNs is tightly co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6040a55b55fb8d70f5ea541116119379
https://pubmed.ncbi.nlm.nih.gov/33581076
https://pubmed.ncbi.nlm.nih.gov/33581076
Autor:
Nahum Sonenberg, Nathaniel Robichaud
Publikováno v:
Current Opinion in Cell Biology. 45:102-109
The evidence for the importance of aberrant translation in cancer cells is overwhelming. Reflecting the wealth of data, there are excellent reviews delineating how ribosomes and initiation factors are linked to cancer [1-3], and the therapeutic strat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e46212f6ef34fb55be9f61436e5736c
https://doi.org/10.1016/j.ceb.2017.05.007
https://doi.org/10.1016/j.ceb.2017.05.007
Autor:
Dana, Pearl, Sakie, Katsumura, Mehdi, Amiri, Negar, Tabatabaei, Xu, Zhang, Valerie, Vinette, Xinhe, Pang, Shawn T, Beug, Sung-Hoon, Kim, Laura M, Jones, Nathaniel, Robichaud, Sang-Ging, Ong, Jian-Jun, Jia, Hamza, Ali, Michel L, Tremblay, Maritza, Jaramillo, Tommy, Alain, Masahiro, Morita, Nahum, Sonenberg, Soroush, Tahmasebi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 204(9)
Deregulation of mRNA translation engenders many human disorders, including obesity, neurodegenerative diseases, and cancer, and is associated with pathogen infections. The role of eIF4E-dependent translational control in macrophage inflammatory respo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e673c7d47e316770023a8d98a1aa6da3
https://pubmed.ncbi.nlm.nih.gov/32213561
https://pubmed.ncbi.nlm.nih.gov/32213561
Autor:
Samuel T Workenhe, Akiko Yanagiya, Huy-Dung Hoang, Soroush Tahmasebi, Dana Pearl, Adrian Pelin, John C. Bell, Chadi Zakaria, Karen L. Mossman, Tyson E. Graber, Jaclyn Hearnden, Polen Sean, Tommy Alain, Jian-Jun Jia, Margaret Watson, Louis-Phillipe Leroux, Seyed Mehdi Jafarnejad, Jean-Simon Diallo, Nahum Sonenberg, Maritza Jaramillo, Nathaniel Robichaud, Vinh Tai Truong, Fabrice Le Boeuf
Publikováno v:
Zakaria, C, Sean, P, Hoang, H-D, Leroux, L-P, Watson, M, Workenhe, S T, Hearnden, J, Pearl, D, Truong, V T, Robichaud, N, Yanagiya, A, Tahmasebi, S, Jafarnejad, S M, Jia, J-J, Pelin, A, Diallo, J-S, Le Boeuf, F, Bell, J C, Mossman, K L, Graber, T E, Jaramillo, M, Sonenberg, N & Alain, T 2018, ' Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis ', PLoS Pathogens, vol. 14, no. 8, e1007264 . https://doi.org/10.1371/journal.ppat.1007264
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2018, 14 (8), pp.e1007264. ⟨10.1371/journal.ppat.1007264⟩
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)
PLoS Pathogens
PLoS Pathogens, Public Library of Science, 2018, 14 (8), pp.e1007264. ⟨10.1371/journal.ppat.1007264⟩
PLoS Pathogens, Vol 14, Iss 8, p e1007264 (2018)
International audience; Herpes Simplex Virus 1 (HSV1) is amongst the most clinically advanced oncolytic virus platforms. However, efficient and sustained viral replication within tumours is limiting. Rapamycin can stimulate HSV1 replication in cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26c92dee5a0216e1929b4920ce8f0aa3
https://pubmed.ncbi.nlm.nih.gov/30138450
https://pubmed.ncbi.nlm.nih.gov/30138450
Autor:
Christophe Goncalves, Nahum Sonenberg, S V del Rincon, William J. Muller, Jaclyn Hearnden, Luc Furic, Luca A. Petruccelli, Tommy Alain, Charles Spruck, Ola Larsson, Nathaniel Robichaud, Wilson H. Miller, Stefan Grotegut, Bonnie Huor
Publikováno v:
Oncogene
The progression of cancers from primary tumors to invasive and metastatic stages accounts for the overwhelming majority of cancer deaths. Understanding the molecular events which promote metastasis is thus critical in the clinic. Translational contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76dbce8e2cf67160ef05a7a583fbdf6f
http://europepmc.org/articles/PMC4978545
http://europepmc.org/articles/PMC4978545