Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nathaniel P. Albert"'
Autor:
Pappanaicken R. Kumaresan, Sebastian Wurster, Karishma Bavisi, Thiago Aparecido da Silva, Paul Hauser, Jordan Kinnitt, Nathaniel D. Albert, Uddalak Bharadwaj, Sattva Neelapu, Dimitrios P. Kontoyiannis
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTInvasive aspergillosis (IA) is a common and deadly mold infection in immunocompromised patients. As morbidity and mortality of IA are primarily driven by poor immune defense, adjunct immunotherapies, such as chimeric antigen receptor (CAR) T
Externí odkaz:
https://doaj.org/article/fd61b7fcf9c5448182177b0185555d31
Publikováno v:
mSphere, Vol 7, Iss 2 (2022)
ABSTRACT Candida auris is a globally spreading yeast pathogen causing bloodstream infections with high mortality in critically ill patients. The inherent antifungal drug resistance of most C. auris isolates and threat of multidrug-resistant strains c
Externí odkaz:
https://doaj.org/article/5b3bf24aa1b04cfea23ad6573120df76
Autor:
Sebastian Wurster, Gabriele Sass, Nathaniel D. Albert, Hasan Nazik, Eric Déziel, David A. Stevens, Dimitrios P. Kontoyiannis
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1329-1336 (2020)
Pseudomonas aeruginosa (PA) and Aspergillus fumigatus (AF) chronically colonize the airways of patients with cystic fibrosis or chronic immunosuppression and mutually affect each other’s pathogenesis. Here, we evaluated IncuCyte time-lapse imaging
Externí odkaz:
https://doaj.org/article/dbc320d2fe6d4e02b5f03d0674e6d4ec
Autor:
Sebastian Wurster, Nathaniel D. Albert, Uddalak Bharadwaj, Moses M. Kasembeli, Jeffrey J. Tarrand, Naval Daver, Dimitrios P. Kontoyiannis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Anecdotal clinical reports suggested a benefit of adjunct immune checkpoint inhibitors (ICIs) to treat invasive mucormycosis. However, proof-of-concept data in animal models and mechanistic insights into the effects of ICIs on host defense against Mu
Externí odkaz:
https://doaj.org/article/e9f620828fa344de9195f0ca913c7e69
Autor:
Sebastian Wurster, Oscar E. Ruiz, Krystin M. Samms, Alexander M. Tatara, Nathaniel D. Albert, Philip H. Kahan, Anh Trinh Nguyen, Antonios G. Mikos, Dimitrios P. Kontoyiannis, George T. Eisenhoffer
Publikováno v:
Cell Reports, Vol 34, Iss 12, Pp 108896- (2021)
Summary: Severe and often fatal opportunistic fungal infections arise frequently following mucosal damage caused by trauma or cytotoxic chemotherapy. Interaction of fungal pathogens with epithelial cells that comprise mucosae is a key early event ass
Externí odkaz:
https://doaj.org/article/090b8750f4e64706818b17aa866b5303
Autor:
Sebastian Wurster, Alexander M. Tatara, Nathaniel D. Albert, Ashraf S. Ibrahim, Joseph Heitman, Soo Chan Lee, Amol C. Shetty, Carrie McCracken, Karen T. Graf, Antonios G. Mikos, Vincent M. Bruno, Dimitrios P. Kontoyiannis
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Trauma-related necrotizing myocutaneous mucormycosis (NMM) has a high morbidity and mortality in victims of combat-related injuries, geometeorological disasters, and severe burns. Inspired by the observation that several recent clusters of N
Externí odkaz:
https://doaj.org/article/1d82ac74355b42f0895c16fb72c03309
Autor:
Sebastian Wurster, Pappanaicken R. Kumaresan, Nathaniel D. Albert, Paul J. Hauser, Russell E. Lewis, Dimitrios P. Kontoyiannis
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Efficient live-imaging methods are pivotal to understand fungal morphogenesis, especially as it relates to interactions with host immune cells and mechanisms of antifungal drugs. Due to the notable similarities in growth patterns of neuronal
Externí odkaz:
https://doaj.org/article/5c45886b39dc445e83d10220e83ba0c0
Autor:
Guangling Liao, Randall A. Prince, Dimitrios P. Kontoyiannis, Weiqun Wang, Russell E. Lewis, Nathaniel P. Albert
Publikováno v:
The Journal of antimicrobial chemotherapy. 68(5)
Received 15 October 2012; returned 21 November 2012; revised 7 December 2012; accepted 13 December 2012 Objectives: Aspergillus terreus is considered to be resistant to amphotericin B (AMB). However, it is unknown whether higher daily doses of liposo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923e3daba6890ea334a269d40122d9d2
https://pubmed.ncbi.nlm.nih.gov/23349440
https://pubmed.ncbi.nlm.nih.gov/23349440