Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nathaniel J. Barton"'
Autor:
Molly Smullen, Meagan N. Olson, Liam F. Murray, Madhusoodhanan Suresh, Guang Yan, Pepper Dawes, Nathaniel J. Barton, Jivanna N. Mason, Yucheng Zhang, Aria A. Fernandez-Fontaine, George M. Church, Diego Mastroeni, Qi Wang, Elaine T. Lim, Yingleong Chan, Benjamin Readhead
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Mitochondrial (MT) dysfunction has been associated with several neurodegenerative diseases including Alzheimer’s disease (AD). While MT-copy number differences have been implicated in AD, the effect of MT heteroplasmy on AD has not been we
Externí odkaz:
https://doaj.org/article/7f133d69551245a7bf77cd609ed77e08
Autor:
Pepper Dawes, Liam F. Murray, Meagan N. Olson, Nathaniel J. Barton, Molly Smullen, Madhusoodhanan Suresh, Guang Yan, Yucheng Zhang, Aria Fernandez-Fontaine, Jay English, Mohammed Uddin, ChangHui Pak, George M. Church, Yingleong Chan, Elaine T. Lim
Publikováno v:
Human Genetics.
Publikováno v:
Nucleic Acids Research
CRISPR-Cas9 sgRNA libraries have transformed functional genetic screening and have enabled several innovative methods that rely on simultaneously targeting numerous genetic loci. Such libraries could be used in a vast number of biological systems and