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pro vyhledávání: '"Nathaniel J Macatangay"'
Autor:
Saayak Halder, Nathaniel J. Macatangay, Breanna L. Zerfas, Andres F. Salazar-Chaparro, Darci J. Trader
Publikováno v:
RSC medicinal chemistry. 13(9)
A series of oleic acid amide derivatives were generated as potential small molecule stimulators of the 20S core particle of the proteasome (20S CP), with the goal of increasing the protein degradation rate via the ubiquitin-independent pathway.
Autor:
Andres F Salazar-Chaparro, Rachel A Coleman, Breanna L. Zerfas, Darci J. Trader, Nathaniel J Macatangay
Publikováno v:
ACS Chem Biol
The proteasome is an essential protein complex that, when dysregulated, can result in various diseases in eukaryotic cells. As such, understanding the enzymatic activity of the proteasome and what can alter it is crucial to elucidating its roles in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac1fa598bcd3c3659cf8052976af087
https://doi.org/10.26434/chemrxiv.12043101
https://doi.org/10.26434/chemrxiv.12043101