Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nathaniel H.O. Harder"'
Autor:
Gaurav V. Sarode, Tagreed A. Mazi, Kari Neier, Noreene M. Shibata, Guillaume Jospin, Nathaniel H.O. Harder, Marie C. Heffern, Ashok K. Sharma, Shyam K. More, Maneesh Dave, Shannon M. Schroeder, Li Wang, Janine M. LaSalle, Svetlana Lutsenko, Valentina Medici
Publikováno v:
bioRxiv
Background and aimsMajor clinical manifestations of Wilson disease (WD) are related to copper accumulation in the liver and the brain, and little is known about other tissues involvement in metabolic changes in WD.In vitrostudies suggested that the l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81091c2d37227a2143f15658b3dbf7d7
https://europepmc.org/articles/PMC9882126/
https://europepmc.org/articles/PMC9882126/
Autor:
Wan Chen Hsieh, James J. Moresco, Eugenio Santelli, Charles C. King, Nathaniel H.O. Harder, John R. Yates, Lin Liu, Mattias Svensson, Stephanie M. Stanford, Shen Yang, Nunzio Bottini, William B. Kiosses
Publikováno v:
Sci Signal
The hematopoietic-specific protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is encoded by a major autoimmunity risk gene. PTPN22 inhibits T cell activation by dephosphorylating substrates involved in proximal T cell receptor (TCR) signaling.