Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nathaniel D Maynard"'
Publikováno v:
Molecular Systems Biology, Vol 8, Iss 1, Pp 1-13 (2012)
Abstract Viral infection depends on a complex interplay between host and viral factors. Here, we link host susceptibility to viral infection to a network encompassing sulfur metabolism, tRNA modification, competitive binding, and programmed ribosomal
Externí odkaz:
https://doaj.org/article/cfe3cb5670c24b3cbd0dfb770a5c8ba3
Autor:
Nathaniel D Maynard, Elsa W Birch, Jayodita C Sanghvi, Lu Chen, Miriam V Gutschow, Markus W Covert
Publikováno v:
PLoS Genetics, Vol 6, Iss 7, p e1001017 (2010)
Latently infecting viruses are an important class of virus that plays a key role in viral evolution and human health. Here we report a genome-scale forward-genetics screen for host-dependencies of the latently-infecting bacteriophage lambda. This scr
Externí odkaz:
https://doaj.org/article/02685568cb664ee6981cabdde93f1dca
Publikováno v:
Proceedings of the National Academy of Sciences
The cell-to-cell spread of cytoplasmic constituents such as nonenveloped viruses and aggregated proteins is usually thought to require cell lysis. However, mechanisms of unconventional secretion have been described that bypass the secretory pathway f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58eeaa4768e50e2a6a92f007c9321e97
https://doi.org/10.1073/pnas.1401437111
https://doi.org/10.1073/pnas.1401437111
Publikováno v:
Biotechnology Journal. 5:686-694
Recent genome-wide screens of host genetic requirements for viral infection have reemphasized the critical role of host metabolism in enabling the production of viral particles. In this review, we highlight the metabolic aspects of viral infection fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa628aa5c8902170beeb80452de32c3
https://doi.org/10.1002/biot.201000080
https://doi.org/10.1002/biot.201000080
Publikováno v:
WIREs Systems Biology and Medicine. 1:285-297
During the last decade, models have been developed to characterize cellular metabolism at the level of an entire metabolic network. The main concept that underlies whole-network metabolic modeling is the identification and mathematical definition of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9ee9c7ef7e8f76aee9c17cc8e8461b
https://doi.org/10.1002/wsbm.37
https://doi.org/10.1002/wsbm.37
Publikováno v:
Nature Methods. 12:i-ii
Since its introduction 6 years ago, the Gibson Assembly method has been widely adopted as a preferred cloning method. Here we describe an application of Gibson Assembly beyond routine cloning: assembly in DNA library construction. Advantages of using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dac1e56090563118c719ef0cb5416318
https://doi.org/10.1038/nmeth.f.384
https://doi.org/10.1038/nmeth.f.384
Autor:
Jayodita C. Sanghvi, Nathaniel D. Maynard, Elissa M. Denny, Jacob J. Hughey, Jahlionais E. Gaston, Timothy K. Lee, Markus W. Covert
Nearly identical cells can exhibit substantially different responses to the same stimulus. We monitored the nuclear localization dynamics of nuclear factor kappaB (NF-kappaB) in single cells stimulated with tumor necrosis factor-alpha (TNF-alpha) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4bc85a208bc7e38b7244ed9ec23507
https://europepmc.org/articles/PMC2778577/
https://europepmc.org/articles/PMC2778577/
