Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nathaniel D Lambert"'
Autor:
Hannah M Salk, Whitney L Simon, Nathaniel D Lambert, Richard B Kennedy, Diane E Grill, Brian F Kabat, Gregory A Poland
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162803 (2016)
Live attenuated influenza vaccine (LAIV) has demonstrated varying levels of efficacy against seasonal influenza; however, LAIV may be used as a tool to measure interactions between the human microbiome and a live, replicating virus. To increase our k
Externí odkaz:
https://doaj.org/article/3db103dadc9e463db5f7f192b470dcd6
Autor:
Iana H Haralambieva, Scott D Painter, Richard B Kennedy, Inna G Ovsyannikova, Nathaniel D Lambert, Krista M Goergen, Ann L Oberg, Gregory A Poland
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0122282 (2015)
Although influenza causes significant morbidity and mortality in the elderly, the factors underlying the reduced vaccine immunogenicity and efficacy in this age group are not completely understood. Age and immunosenescence factors, and their impact o
Externí odkaz:
https://doaj.org/article/15ec97be221641c685f8d34f0207559d
Autor:
Iana H Haralambieva, Nathaniel D Lambert, Inna G Ovsyannikova, Richard B Kennedy, Beth R Larrabee, V Shane Pankratz, Gregory A Poland
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99997 (2014)
Viral attachment and cell entry host factors are important for viral replication, pathogenesis, and the generation and sustenance of immune responses after infection and/or vaccination, and are plausible genetic regulators of vaccine-induced immunity
Externí odkaz:
https://doaj.org/article/707c792cd74645c1a4ee18b356296eda
Autor:
Nathaniel D. Lambert, Inna G. Ovsyannikova, Vernon S. Pankratz, Richard B. Kennedy, Iana H. Haralambieva, Gregory A. Poland
Publikováno v:
Journal of Infectious Diseases. 211:898-905
Vaccination with live attenuated rubella virus induces a strong immune response in most individuals. However, small numbers of subjects never reach or maintain protective antibody levels, and there is a high degree of variability in immune response.
Autor:
Iana H. Haralambieva, Gregory A. Poland, Nathaniel D. Lambert, Inna G. Ovsyannikova, Richard B. Kennedy, V. Shane Pankratz
Publikováno v:
Human Genetics. 133:1407-1417
Rubella virus causes a relatively benign disease in most cases, although infection during pregnancy can result in serious birth defects. An effective vaccine has been available since the early 1970s and outbreaks typically do not occur among highly v
Autor:
Iana H. Haralambieva, Gregory A. Poland, Richard B. Kennedy, Inna G. Ovsyannikova, V. Shane Pankratz, Nathaniel D. Lambert
Publikováno v:
Immunogenetics. 66:493-499
Genetic polymorphisms are known to affect responses to both viral infection and vaccination. Our previous work has described genetic polymorphisms significantly associated with variations in immune response to rubella vaccine from multiple gene famil
Autor:
Iana H. Haralambieva, Gregory A. Poland, Richard B. Kennedy, Inna G. Ovsyannikova, Nathaniel D. Lambert
Publikováno v:
Expert Review of Vaccines
The impact of vaccines on public health and well-being has been profound. Smallpox has been eradicated, polio is nearing eradication, and multiple diseases have been eliminated from certain areas of the world. Unfortunately, we now face diseases such
Autor:
Iana H. Haralambieva, Gregory A. Poland, Nathaniel D. Lambert, V. Shane Pankratz, Inna G. Ovsyannikova, Beth R. Larrabee
Publikováno v:
Immunologic Research. 58:1-8
Although vaccination campaigns have significantly reduced the global burden of rubella disease, there are still regional outbreaks and cases of congenital rubella syndrome. Rubella vaccination elicits a strong humoral as well as cellular response. Th
Autor:
Nathaniel D. Lambert, Ann L. Oberg, Gregory A. Poland, Robert M. Jacobson, Brett A. McKinney, Inna G. Ovsyannikova, Richard B. Kennedy
Publikováno v:
Seminars in Immunology. 25:89-103
Vaccines, like drugs and medical procedures, are increasingly amenable to individualization or personalization, often based on novel data resulting from high throughput “omics” technologies. As a result of these technologies, 21st century vaccino
Autor:
Gregory A. Poland, Nathaniel D. Lambert, Robert M. Jacobson, V. Shane Pankratz, Inna G. Ovsyannikova
Publikováno v:
Expert Review of Vaccines. 11:985-994
Annual vaccination against seasonal influenza is recommended to decrease disease-related mortality and morbidity. However, one population that responds suboptimally to influenza vaccine is adults over the age of 65 years. The natural aging process is