Effect of isoniazid preventive therapy on risk of death in west African, HIV-infected adults with high CD4 cell counts: long-term follow-up of the Temprano ANRS 12136 trial

Autor: Anani Badje, MPH, Raoul Moh, PhD, Delphine Gabillard, MSc, Calixte Guéhi, PhD, Mathieu Kabran, PharmD, Jean-Baptiste Ntakpé, MPH, Jérôme Le Carrou, PhD, Gérard M Kouame, MPH, Eric Ouattara, PhD, Eugène Messou, PhD, Amani Anzian, MD, Albert Minga, PhD, Joachim Gnokoro, MD, Patrice Gouesse, MD, Arlette Emieme, PharmD, Thomas-d'Aquin Toni, PhD, Cyprien Rabe, MD, Baba Sidibé, MD, Gustave Nzunetu, MD, Lambert Dohoun, MD, Abo Yao, MPH, Synali Kamagate, MD, Solange Amon, MD, Amadou-Barenson Kouame, MD, Aboli Koua, MD, Emmanuel Kouamé, MD, Marcelle Daligou, MD, Denise Hawerlander, MD, Simplice Ackoundzé, MD, Serge Koule, MD, Jonas Séri, MD, Alex Ani, MD, Fassery Dembélé, MD, Fatoumata Koné, MD, Mykayila Oyebi, MD, Nathalie Mbakop, MD, Oyewole Makaila, MD, Carolle Babatunde, MD, Nathaniel Babatunde, MD, Gisèle Bleoué, MD, Mireille Tchoutedjem, MD, Alain-Claude Kouadio, MD, Ghislaine Sena, MD, Sahinou-Yediga Yededji, MD, Sophie Karcher, MSc, Prof Christine Rouzioux, PhD, Abo Kouame, MD, Rodrigue Assi, MD, Alima Bakayoko, MD, Prof Serge K Domoua, PhD, Nina Deschamps, MPH, Prof Kakou Aka, MD, Prof Thérèse N'Dri-Yoman, MD, Prof Roger Salamon, PhD, Valérie Journot, PhD, Prof Hughes Ahibo, PhD, Prof Timothée Ouassa, PhD, Prof Hervé Menan, PhD, Prof André Inwoley, PhD, Christine Danel, PhD, Prof Serge P Eholié, PhD, Dr Xavier Anglaret, PhD, Anani Badje, Raoul Moh, Delphine Gabillard, Calixte Guéhi, Mathieu Kabran, Jean-Baptiste Ntakpé, Jérôme Le Carrou, Gérard-Menan Kouame, Eric Ouattara, Eugène Messou, Amani Anzian, Albert Minga, Joachim Gnokoro, Patrice Gouesse, Arlette Emieme, Thomas-d'Aquin Toni, Cyprien Rabe, Baba Sidibé, Gustave Nzunetu, Lambert Dohoun, Yao Abo, Synali Kamagate, Solange Amon, Amadou-Barenson Kouame, Aboli Koua, Emmanuel Kouamé, Marcelle Daligou, Denise Hawerlander, Simplice Ackoundzé, Serge Koule, Jonas Séri, Alex Ani, Fassery Dembélé, Fatoumata Koné, Mykayila Oyebi, Nathalie Mbakop, Oyewole Makaila, Carolle Babatunde, Nathaniel Babatunde, Gisèle Bleoué, Mireille Tchoutedjem, Alain-Claude Kouadio, Ghislaine Sena, Sahinou-Yediga Yededji, Sophie Karcher, Christine Rouzioux, Abo Kouame, Rodrigue Assi, Alima Bakayoko, Serge-K. Domoua, Nina Deschamps, Kakou Aka, Thérèse N'Dri-Yoman, Roger Salamon, Valérie Journot, Hughes Ahibo, Timothée Ouassa, Hervé Ménan, André Inwoley, Ben-Ahoussi Ndja, Blandine Adou, Constance Kanga, Eba Aoussi, Emmanuel Bissagnene, Olivier Ba-Gomis, Yves-Alain Zike, Claude Akakpo, Madeleine Sassan-Morokro, Max Mobio, Bamba Doféré, Koman Mesmin, Alain Attia, Alassane Mahassadi, Apollinaire Horo, Armel Oussou, Marie-Laure Chaix, Gilles Peytavin, Mariatou Koné, Kouamé N'Guessan, Raïmi Fassassi, Serge Niangoran, Annabel Desgrées-du-Loû, France Lert, Rosemary Dray Spira, Kevin Jean, Romuald Konan, Franck Bohoussou, Cyril Yao-Yapi, Larissa N'guessan-Koffi, Bertine Siloué, Adoulaye Cissé, Adrienne Aboua, Sylvie Konan, Antoine Kouamé, Celestin N'Chot, Elvis Amani, Gwenaëlle Clouet, Bruno Debono, Geneviève Chêne, Mireille Dosso, Pierre-Marie Girard, Vincent Jarlier, Jean-Marie Masumbuko, Christian Perronne, Papa-Salif Sow, Christine Danel, Serge-Paul Eholié, Xavier Anglaret

Publikováno v: The Lancet Global Health, Vol 5, Iss 11, Pp e1080-e1089 (2017)

Background: Temprano ANRS 12136 was a factorial 2 × 2 trial that assessed the benefits of early antiretroviral therapy (ART; ie, in patients who had not reached the CD4 cell count threshold used to recommend starting ART, as per the WHO guidelines t

Externí odkaz: https://doaj.org/article/c5d7eb49263d4e08a3d2d62ed936400d