Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nathaniel A Jeske"'
Autor:
Elaine D Por, Melody L Sandoval, Chiquita Thomas-Benson, Teresa A Burke, Allison Doyle Brackley, Nathaniel A Jeske, Jeffery M Cleland, Brian J Lund
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182102 (2017)
Blast-associated sensory and cognitive trauma sustained by military service members is an area of extensively studied research. Recent studies in our laboratory have revealed that low-level blast exposure increased expression of transient receptor po
Externí odkaz:
https://doaj.org/article/69724b78f4d5470f9fec116a82b2d094
Publikováno v:
ASN Neuro, Vol 7 (2015)
Endothelin-1 (ET-1) and bradykinin (BK) are endogenous peptides that signal through Gαq/11-protein coupled receptors (GPCRs) to produce nociceptor sensitization and pain. Both peptides activate phospholipase C to stimulate Ca 2+ accumulation, diacyl
Externí odkaz:
https://doaj.org/article/b5a9fc565b2c46a89c9afa0112421c10
Autor:
Matthew P Rowan, Sonya M Bierbower, Michael A Eskander, Kalina Szteyn, Elaine D Por, Ruben Gomez, Nicholas Veldhuis, Nigel W Bunnett, Nathaniel A Jeske
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93688 (2014)
The transient receptor potential family V1 channel (TRPV1) is activated by multiple stimuli, including capsaicin, acid, endovanilloids, and heat (>42C). Post-translational modifications to TRPV1 result in dynamic changes to the sensitivity of recepto
Externí odkaz:
https://doaj.org/article/174209bf0b7846cfbc51fe6c24594614
Autor:
Allison Doyle Brackley, Ruben Gomez, Kristi A. Guerrero, Armen N. Akopian, Marc J. Glucksman, Junhui Du, Susan M. Carlton, Nathaniel A. Jeske
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Mechanical pain serves as a base clinical symptom for many of the world’s most debilitating syndromes. Ion channels expressed by peripheral sensory neurons largely contribute to mechanical hypersensitivity. Transient Receptor Potential A 1
Externí odkaz:
https://doaj.org/article/78d62c56f9cc4d618d2eefe60eaa2041
Autor:
Felix Jose Amarista, Jason P. Jones, Zachary Brown, Denae C. Rushing, Nathaniel A. Jeske, Daniel E. Perez
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology. 134:135-142
The purpose of this study was to evaluate subjective and objective outcomes in patients with temporomandibular joint (TMJ) ankylosis treated with TMJ alloplastic reconstruction (TMJR).All patients diagnosed with TMJ ankylosis that underwent TMJR at o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2ec77f3e02d71cba5406e913ca9a76
https://doi.org/10.1016/j.oooo.2021.12.121
https://doi.org/10.1016/j.oooo.2021.12.121
Publikováno v:
Journal of Neurochemistry. 162:156-165
Inflammatory hyperalgesia represents a nociceptive phenotype that can become persistent in nature through dynamic protein modifications. However, a large gap in knowledge exists concerning how the integration of intracellular signaling molecules coor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3876521c5cd6d4711b24d42e7575262d
https://doi.org/10.1111/jnc.15614
https://doi.org/10.1111/jnc.15614
Publikováno v:
eNeuro.
There are currently no Food and Drug Administration (FDA)-approved δ-opioid receptor (DOR)-selective agonists, despite having fewer side effects in rodents and nonhuman primates compared with traditional μ-opioid receptor (MOR) therapeutics (Vander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae799bbbb01010c388620e33bc8159b
https://pubmed.ncbi.nlm.nih.gov/35882549
https://pubmed.ncbi.nlm.nih.gov/35882549
Publikováno v:
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons. 80(5)
An extension of digital technology is to provide patient-specific hardware to reposition the first jaw in a bimaxillary case without the use of an intermediate splint. The purpose of our study was to determine if there were significant differences in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae1dd4a22d53ffa84bc939f165bccd4
https://pubmed.ncbi.nlm.nih.gov/35151639
https://pubmed.ncbi.nlm.nih.gov/35151639
Autor:
Nathaniel A. Jeske
Publikováno v:
Molecular Pharmacology
Opioids serve a vital role in the current analgesic array of treatment options. They are useful in acute instances involving severe pain associated with trauma, surgery, and terminal diseases such as cancer. In the past three decades, multiple recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12aed16a990b70f5ff4a850f31298ff2
https://doi.org/10.1124/mol.118.114637
https://doi.org/10.1124/mol.118.114637
Autor:
Nathaniel A. Jeske, Yan Zhang
Publikováno v:
ACS Chem Neurosci
The peripheral mu-opioid receptor (MOR) has been recognized as a potential target to provide safer analgesia with reduced central side effects. Although analgesic incompetence of the peripheral MOR in the absence of inflammation was initially identif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067d85d2a126030bb235fcf7a04ffc7e
https://pubmed.ncbi.nlm.nih.gov/33174729
https://pubmed.ncbi.nlm.nih.gov/33174729