Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches

Autor: Eric J. Bennett, Bing Yang, Jeffrey Liao, Arit Ghosh, Nathan Zuzow, Marilyn Leonard

Publikováno v: Molecular Biology of the Cell
Molecular biology of the cell, vol 29, iss 10

Previous genetic and biochemical studies from Saccharomyces cerevisiae have identified a critical ribosome-associated quality control complex (RQC) that facilitates resolution of stalled ribosomal complexes. While components of the mammalian RQC have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e607dc9204ec8e0bac957c11313e065e
https://doi.org/10.1091/mbc.e17-12-0714

The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins

Autor: Raymond H. Mak, Paul Riviere, Scott A. Lindsay, Randolph Y. Hampton, John C. Christianson, Eric J. Bennett, Reneé Higgins, Joshua M. Gendron, Nathan Zuzow, Emma J. Fenech, Bing Yang, Steven A. Wasserman, Xin Tang, Lisa Rising, Stephen E. Kaiser, Kristofor J. Webb

Publikováno v: Higgins, R; Gendron, JM; Rising, L; Mak, R; Webb, K; Kaiser, SE; et al.(2015). The Unfolded Protein Response Triggers Site-Specific Regulatory Ubiquitylation of 40S Ribosomal Proteins. Molecular Cell, 59(1), 35-49. doi: 10.1016/j.molcel.2015.04.026. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/9z59x2fg
Molecular cell, vol 59, iss 1

© 2015 Elsevier Inc. Insults to ER homeostasis activate the unfolded protein response (UPR), which elevates protein folding and degradation capacity and attenuates protein synthesis. While a role for ubiquitin in regulating thedegradation of misfold

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27f7770e252349e536b50c8dc8faf19
http://www.escholarship.org/uc/item/9z59x2fg