Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Nathan W Cummins"'
Autor:
Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Vesna D Garovic, Andrew Limper
Publikováno v:
BMJ Open, Vol 12, Iss 7 (2022)
Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The U
Externí odkaz:
https://doaj.org/article/01cac24c43d947158fb04132bc066467
Autor:
Nathan W Cummins, Jason Baker, Rana Chakraborty, Patrick G Dean, Enrique Garcia-Rivera, Ashton Krogman, Shaji Kumar, Yury V Kuzmichev, Gregory M Laird, Alan Landay, Mathias Lichterfeld, Maryam Mahmood, Jeffrey Martinson, Mark Maynes, Sekar Natesampillai, Vincent Rajkumar, Yelizaveta Rassadkina, Kristen D. Ritter, Christina G Rivera, Stacey A Rizza, Krupa Subramanian, Aaron J Tande, Elizabeth R Wonderlich, Jennifer A Whitaker, John Zeuli, Andrew D Badley
Publikováno v:
EClinicalMedicine, Vol 42, Iss , Pp 101225- (2021)
Background: Achieving a functional or sterilizing cure for HIV will require identification of therapeutic interventions that reduce HIV reservoir size in infected individuals. Proteasome inhibitors, such as ixazomib, impact multiple aspects of HIV bi
Externí odkaz:
https://doaj.org/article/9bcbc1806c0c4535bde930e29c873a95
Autor:
Molly Moore Jeffery, Nilay D Shah, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Andrew H. Limper
Publikováno v:
BMJ Open, Vol 11, Iss 3 (2021)
Objectives Evaluate associations between ACE inhibitors (ACEis) and angiotensin receptor blockers (ARBs) and clinical outcomes in acute viral respiratory illness (AVRI).Design Retrospective cohort analysis of claims data.Setting The USA; 2018–2019
Externí odkaz:
https://doaj.org/article/2f0d1331ce4d427b8d355cd66ce7887f
Autor:
Andrea J French, Sekar Natesampillai, Ashton Krogman, Cristina Correia, Kevin L Peterson, Alecia Alto, Aswath P Chandrasekar, Anisha Misra, Ying Li, Scott H Kaufmann, Andrew D Badley, Nathan W Cummins
Publikováno v:
PLoS Pathogens, Vol 16, Iss 10, p e1008906 (2020)
Eradication of HIV-1 by the "kick and kill" strategy requires reactivation of latent virus to cause death of infected cells by either HIV-induced or immune-mediated apoptosis. To date this strategy has been unsuccessful, possibly due to insufficient
Externí odkaz:
https://doaj.org/article/43ec5f6e91a24ab2bbc1bd2c4e5d59c0
Autor:
Nathan W Cummins, Stacey Rizza, Mark R Litzow, Stephane Hua, Guinevere Q Lee, Kevin Einkauf, Tae-Wook Chun, Frank Rhame, Jason V Baker, Michael P Busch, Nicolas Chomont, Patrick G Dean, Rémi Fromentin, Ashley T Haase, Dylan Hampton, Sheila M Keating, Steven M Lada, Tzong-Hae Lee, Sekar Natesampillai, Douglas D Richman, Timothy W Schacker, Stephen Wietgrefe, Xu G Yu, Joseph D Yao, John Zeuli, Mathias Lichterfeld, Andrew D Badley
Publikováno v:
PLoS Medicine, Vol 14, Iss 11, p e1002461 (2017)
BACKGROUND:Notwithstanding 1 documented case of HIV-1 cure following allogeneic stem cell transplantation (allo-SCT), several subsequent cases of allo-SCT in HIV-1 positive individuals have failed to cure HIV-1 infection. The aim of our study was to
Externí odkaz:
https://doaj.org/article/6cb0f7ce4309430794213dddfb5bf122
Autor:
Rahul Sampath, Nathan W Cummins, Sekar Natesampillai, Gary D Bren, Thomas D Chung, Jason Baker, Keith Henry, Amélie Pagliuzza, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179327 (2017)
HIV persists because a reservoir of latently infected CD4 T cells do not express viral proteins and are indistinguishable from uninfected cells. One approach to HIV cure suggests that reactivating HIV will activate cytotoxic pathways; yet when tested
Externí odkaz:
https://doaj.org/article/fbe979067c1142899383a6144c7300a9
Autor:
Jasmine R Marcelin, Melody L Berg, Eugene M Tan, Hatem Amer, Nathan W Cummins, Stacey A Rizza
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149562 (2016)
BACKGROUND:Risk factors for and optimal surveillance of renal dysfunction in patients on tenofovir disoproxil fumarate (TDF) remain unclear. We investigated whether a urine protein-osmolality (P/O) ratio would be associated with renal dysfunction in
Externí odkaz:
https://doaj.org/article/553d0521a10a45798c44488702edafd8
Autor:
Nathan W Cummins, Anna Klicpera, Amy M Sainski, Gary D Bren, Sundeep Khosla, Jennifer J Westendorf, Andrew D Badley
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24876 (2011)
Patients with HIV infection have decreased numbers of osteoblasts, decreased bone mineral density and increased risk of fracture compared to uninfected patients; however, the molecular mechanisms behind these associations remain unclear. We questione
Externí odkaz:
https://doaj.org/article/8d1ea0a6bb65496fac755409464d7227
Autor:
Sekar Natesampillai, Zilin Nie, Nathan W Cummins, Dirk Jochmans, Gary D Bren, Jonathan B Angel, Andrew D Badley
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001213 (2010)
In medicine, understanding the pathophysiologic basis of exceptional circumstances has led to an enhanced understanding of biology. We have studied the circumstance of HIV-infected patients in whom antiretroviral therapy results in immunologic benefi
Externí odkaz:
https://doaj.org/article/143cdd7991584c8080240d814977a14a
Autor:
Huma Saeed, Edison J. Cano, Mohammad Qasim Khan, Zachary A. Yetmar, Byron Smith, Stacey A. Rizza, Andrew D. Badley, Maryam Mahmood, Michael D. Leise, Nathan W. Cummins
Publikováno v:
Life, Vol 12, Iss 11, p 1755 (2022)
Combination anti-retroviral therapy has drastically improved solid organ transplantation outcomes in persons living with HIV. DAA therapy has led to the successful eradication of HCV. While recent data have suggested improvement in outcomes in HIV/HC
Externí odkaz:
https://doaj.org/article/c9fac98bb0cc468f90f27a73257fe126