Zobrazeno 1 - 10
of 128
pro vyhledávání: '"Nathan W Bartlett"'
Autor:
Stephanie Traub, Alexandra Nikonova, Alan Carruthers, Rebecca Dunmore, Katherine A Vousden, Leila Gogsadze, Weidong Hao, Qing Zhu, Katie Bernard, Jie Zhu, Michael Dymond, Gary R McLean, Ross P Walton, Nicholas Glanville, Alison Humbles, Musa Khaitov, Ted Wells, Roland Kolbeck, Andrew J Leishman, Matthew A Sleeman, Nathan W Bartlett, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003520 (2013)
Human rhinoviruses (HRV) cause the majority of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Effective therapies are urgently needed, but no licensed treatments or vaccines currently exist. Of the 10
Externí odkaz:
https://doaj.org/article/4f4766f10a70461e92a26bb6d95085f3
Autor:
Nicholas Glanville, Gary R McLean, Bruno Guy, Valerie Lecouturier, Catherine Berry, Yves Girerd, Christophe Gregoire, Ross P Walton, Rebecca M Pearson, Tatiana Kebadze, Nicolas Burdin, Nathan W Bartlett, Jeffrey W Almond, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003669 (2013)
Human rhinovirus (RV) infections are the principle cause of common colds and precipitate asthma and COPD exacerbations. There is currently no RV vaccine, largely due to the existence of ∼150 strains. We aimed to define highly conserved areas of the
Externí odkaz:
https://doaj.org/article/07717b4341ab44fc8f7b80ae6c35376c
Autor:
Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001178 (2010)
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epit
Externí odkaz:
https://doaj.org/article/7aaa3892a9194b66b016b415e301e757
Autor:
Alane Blythe C. Dy, Jason Girkin, Antonella Marrocco, Adam Collison, Chimwemwe Mwase, Michael J. O’Sullivan, Thien-Khoi N. Phung, Joerg Mattes, Cynthia Koziol-White, James E. Gern, Yury A. Bochkov, Nathan W. Bartlett, Jin-Ah Park
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Rhinovirus (RV) infection of airway epithelial cells triggers asthma exacerbations, during which airway smooth muscle (ASM) excessively contracts. Due to ASM contraction, airway epithelial cells become mechanically compressed. We
Externí odkaz:
https://doaj.org/article/6d91833041f34be599ab4fc5a6112907
Autor:
Anouschka Akerman, Vanessa Milogiannakis, Tyra Jean, Camille Esneau, Mariana Ruiz Silva, Timothy Ison, Christina Fichter, Joseph A. Lopez, Deborah Chandra, Zin Naing, Joanna Caguicla, Daiyang Li, Gregory Walker, Supavadee Amatayakul-Chantler, Nathan Roth, Sandro Manni, Thomas Hauser, Thomas Barnes, Anna Condylios, Malinna Yeang, Maureen Wong, Charles S.P. Foster, Kenta Sato, Sharon Lee, Yang Song, Lijun Mao, Allison Sigmund, Amy Phu, Ann Marie Vande More, Stephanie Hunt, Mark Douglas, Ian Caterson, Warwick Britton, Kerrie Sandgren, Rowena Bull, Andrew Lloyd, Jamie Triccas, Stuart Tangye, Nathan W. Bartlett, David Darley, Gail Matthews, Damien J. Stark, Kathy Petoumenos, William D. Rawlinson, Ben Murrell, Fabienne Brilot, Anthony L. Cunningham, Anthony D. Kelleher, Anupriya Aggarwal, Stuart G. Turville
Publikováno v:
EBioMedicine, Vol 90, Iss , Pp 104545- (2023)
Summary: Background: The Omicron era of the COVID-19 pandemic commenced at the beginning of 2022 and whilst it started with primarily BA.1, it was latter dominated by BA.2 and the related sub-lineage BA.5. Following resolution of the global BA.5 wave
Externí odkaz:
https://doaj.org/article/c20ddc7898f64d7197436749654ce9c9
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 5, Pp 296-303 (2020)
Abstract Growth factor receptors are known to be involved in the process of viral infection. Many viruses not only use growth factor receptors to physically attach to the cell surface and internalize, but also divert receptor tyrosine kinase signalin
Externí odkaz:
https://doaj.org/article/083d7285d47b43419f87f0e43f2d27ff
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L652-L665
Club cells are found in human small airways where they play an important role in immune defense, xenobiotic metabolism, and repair after injury. Over the past few years, data from single-cell RNA sequencing (scRNA-seq) studies has generated new insig
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 324:L48-L52
Autor:
Punnam Chander Veerati, Kristy S. Nichol, Jane M. Read, Nathan W. Bartlett, Peter A. B. Wark, Darryl A. Knight, Christopher L. Grainge, Andrew T. Reid
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 323:L495-L502
Primary bronchial epithelial cells (pBECs) obtained from donors have limited proliferation capacity. Recently, conditional reprogramming (CR) technique has overcome this and has provided the potential for extended passaging and subsequent differentia
Autor:
Bilal Malik, Nathan W. Bartlett, John W. Upham, Kristy S. Nichol, John Harrington, Peter A. B. Wark
Publikováno v:
Respirology.