Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Nathan S. Duncan"'
1
Akademický článek
Ethyl 3-(9-chloro-10-oxo-9,10-dihydroanthracen-9-yl)-5-methylisoxazole-4-carboxylate
Autor: Nathan S. Duncan, Howard D. Beall, Alison K. Kearns, Chun Li, Nicholas R. Natale
Publikováno v: Acta Crystallographica Section E, Vol 70, Iss 3, Pp o315-o316 (2014)
The asymmetric unit of the title compound, C21H16ClNO4, contains two independent molecules (A and B), each adopting a conformation wherein the isoxazole ring is roughly orthogonal to the anthrone ring. The dihedral angle between the mean plane of the
Externí odkaz: https://doaj.org/article/3f239835eae440b98623eeb8038f4b01
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2
Akademický článek
Ethyl 3-(10-bromoanthracen-9-yl)-5-methyl-1,2-oxazole-4-carboxylate
Autor: Nicholas R. Natale, Janet L. Hunting, Nathan S. Duncan, Matthew J. Weaver, Chun Li, Michael J. Campbell
Publikováno v: Acta Crystallographica Section E, Vol 69, Iss 12, Pp o1804-o1805 (2013)
In the title compound, C21H16BrNO3, the mean planes of the anthracene tricycle and isoxazole ring are inclined to each other at a dihedral angle of 72.12 (7)°. The carboxy group is slightly out of the isoxazole mean plane, with a maximum deviation o
Externí odkaz: https://doaj.org/article/5e4a5ec02e2b42f4a81874aa8598e63c
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3
10-Alkoxy-anthracenyl-isoxazole analogs have sub-micromolar activity against a Glioblastoma multiforme cell line
Autor: Nathan S, Duncan, Michael J, Campbell, Donald S, Backos, Chun, Li, Kevin C, Rider, Sascha, Stump, Matthew J, Weaver, Mariusz P, Gajewski, Howard D, Beall, Philip, Reigan, Nicholas R, Natale
Publikováno v: Bioorganic & Medicinal Chemistry. 69:116911
A series of 10-alkoxy-Anthryl-isoxazole-pyrrole-doubletails (RO-AIMs) were synthesized using a crown ether assisted nucleophilic aromatic substitution followed by a modified Schotten-Baumann reaction. The novel RO-AIMs described here exhibit robust g
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccee4d5afc7462c5948103272ecee7bc
https://doi.org/10.1016/j.bmc.2022.116911
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5
Synthesis of New Quinolinequinone Derivatives and Preliminary Exploration of their Cytotoxic Properties
Autor: Charles M. Keyari, Emily A. Eickholt, Nathan S. Duncan, Philippe Diaz, Alison K. Kearns, Howard D. Beall, Geoffrey Abbott
A series of 7-amino- and 7-acetamidoquinoline-5,8-diones with aryl substituents at the 2-position were synthesized, characterized, and evaluated as potential NAD(P)H:quinone oxidoreductase (NQO1) -directed antitumor agents. The synthesis of lavendamy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeeff1b75253a000b5fb4051b7acf8cc
https://europepmc.org/articles/PMC3752426/
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6
Ethyl 3-(9-chloro-10-oxo-9,10-di­hydro­anthracen-9-yl)-5-methyl­isoxazole-4-carboxyl­ate
Autor: Nicholas R. Natale, Alison K. Kearns, Howard D. Beall, Nathan S. Duncan, Chun Li
Publikováno v: Acta Crystallographica Section E: Structure Reports
Acta Crystallographica Section E, Vol 70, Iss 3, Pp o315-o316 (2014)
The asymmetric unit of the title compound, C21H16ClNO4, contains two independent molecules (AandB), each adopting a conformation wherein the isoxazole ring is roughly orthogonal to the anthrone ring. The dihedral angle between the mean plane of the i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1713abf10442a2595737a15e3c3f746f
http://europepmc.org/articles/PMC3998422
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7
Ethyl 3-(10-bromoanthracen-9-yl)-5-methyl-1,2-oxazole-4-carboxylate
Autor: Nathan S. Duncan, Nicholas R. Natale, Matthew J. Weaver, Chun Li, Janet L. Hunting, Michael J. Campbell
Publikováno v: Acta Crystallographica Section E, Vol 69, Iss 12, Pp o1804-o1805 (2013)
Acta Crystallographica Section E: Structure Reports
In the title compound, C21H16BrNO3, the mean planes of the anthracene tricycle and isoxazole ring are inclined to each other at a dihedral angle of 72.12 (7)°. The carboxy group is slightly out of the isoxazole mean plane, with a maximum deviation o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ae2989390e3cf285cc5a8f77868489
https://doi.org/10.1107/s1600536813031395
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