Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nathan S Alexander"'
Autor:
Nathan S Alexander, Richard A Stein, Hanane A Koteiche, Kristian W Kaufmann, Hassane S McHaourab, Jens Meiler
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72851 (2013)
An increasingly used parameter in structural biology is the measurement of distances between spin labels bound to a protein. One limitation to these measurements is the unknown position of the spin label relative to the protein backbone. To overcome
Externí odkaz:
https://doaj.org/article/04ec2ad22c394b5493816ad6c96dc733
Autor:
Alyssa D. Lokits, Julia Koehler Leman, Kristina E. Kitko, Nathan S. Alexander, Heidi E. Hamm, Jens Meiler
Publikováno v:
AIMS Biophysics, Vol 2, Iss 4, Pp 630-648 (2015)
Cell signaling is a fundamental process for all living organisms. G protein-coupled receptors (GPCRs) are a large and diverse group of transmembrane receptors which convert extracellular signals into intracellular responses primarily via coupling to
Externí odkaz:
https://doaj.org/article/e9d9688d99ea48a5a3a032bc8232b8db
Autor:
Marina M. Shenouda, Wenyu Sun, Beata Jastrzebska, Joseph T. Ortega, Sahil Gulati, Nathan S. Alexander, Kota Katayama, Krzysztof Palczewski
Publikováno v:
Journal of Biological Chemistry. 294:6082-6093
The variable composition of the chromophore-binding pocket in visual receptors is essential for vision. The visual phototransduction starts with the cis-trans isomerization of the retinal chromophore upon absorption of photons. Despite sharing the co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::581214df778c99b0dc27b807dc320e42
https://doi.org/10.1074/jbc.ra119.007587
https://doi.org/10.1074/jbc.ra119.007587
Autor:
Marvin T. Nieman, Krzysztof Palczewski, Xu Han, Lukas Hofmann, Nathan S. Alexander, Maria de la Fuente
Publikováno v:
Blood. 136(19)
Protease-activated receptor 4 (PAR4) mediates sustained thrombin signaling in platelets and is required for a stable thrombus. PAR4 is activated by proteolysis of the N terminus to expose a tethered ligand. The structural basis for PAR4 activation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74327a71030ea35fd3a8291afe4cbe22
https://pubmed.ncbi.nlm.nih.gov/33152086
https://pubmed.ncbi.nlm.nih.gov/33152086
Publikováno v:
Protein Science. 26:2118-2125
Dedicated computing resources are expensive to develop, maintain, and administrate. Frequently, research groups require bursts of computing power, during which progress is still limited by available computing resources. One way to alleviate this bott
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b1f7e5a0983537348616f538a919151
https://doi.org/10.1002/pro.3247
https://doi.org/10.1002/pro.3247
Publikováno v:
Pediatric Pulmonology, Asthma, and Sleep Medicine: A Quick Reference Guide ISBN: 9781610021432
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f45e74d9349c2793a760aeed53d41499
https://doi.org/10.1542/9781610021432-part02-ch10
https://doi.org/10.1542/9781610021432-part02-ch10
Autor:
Wenyu Sun, Beata Jastrzebska, Muneto Mogi, Nathan S. Alexander, Sahil Gulati, Jianye Zhang, David Salom, Kota Katayama, Krzysztof Palczewski
Publikováno v:
The Journal of biological chemistry. 292(26)
Phototransduction is initiated when the absorption of light converts the 11-cis-retinal chromophore to its all-trans configuration in both rod and cone vertebrate photoreceptors. To sustain vision, 11-cis-retinal is continuously regenerated from its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c50f8df92916f4501e7083a1493969
https://pubmed.ncbi.nlm.nih.gov/28487362
https://pubmed.ncbi.nlm.nih.gov/28487362
Autor:
Gina N. Wilson, Nathan S. Alexander, Caroline M. Peckels, Joel M. Karty, Kathryn Mansfield Matera
Publikováno v:
Current Enzyme Inhibition. 9:67-74
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::296b1db515945db427ce42a327c4f5dc
https://doi.org/10.2174/1573408011309010009
https://doi.org/10.2174/1573408011309010009
Autor:
Eric J. Sorscher, Stephen B. Hicks, Angela Blount, Shaoyan Zhang, Michael Chestnut, Bradford A. Woodworth, Nathan S. Alexander, Daniel Skinner, Frederick A. Kebbel
Publikováno v:
The Laryngoscope. 122:1193-1197
Objectives/Hypothesis: Evidence indicates that decreased mucociliary clearance (MCC) is a major contributing feature to chronic rhinosinusitis. Tobacco-smoke exposure is thought to inhibit transepithelial Cl− secretion, a major determinant of airwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b5e1a1f9e6429224f5723c6b1f3cf2
https://doi.org/10.1002/lary.23278
https://doi.org/10.1002/lary.23278
Autor:
Bradford A. Woodworth, Shaoyan Zhang, Nathan S. Alexander, Eric J. Sorscher, Daniel Skinner, James A. Fortenberry, Neal U Hatch
Publikováno v:
The Laryngoscope. 121:1313-1319
Objective/Hypothesis: Therapeutic agents that enhance mucociliary transport (via stimulation of transepithelial Cl− secretion) and inhibit inflammation could provide considerable advantages over conventional treatments for chronic rhinosinusitis (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78ffa1b1e7294bc4a96b735175dbbe54
https://doi.org/10.1002/lary.21798
https://doi.org/10.1002/lary.21798