Výsledky vyhledávání - "Nathan Ryan Brady"

Akademický článek

Agent-Based Modeling of Mitochondria Links Sub-Cellular Dynamics to Cellular Homeostasis and Heterogeneity.

Autor: Giovanni Dalmasso, Paula Andrea Marin Zapata, Nathan Ryan Brady, Anne Hamacher-Brady

Publikováno v: PLoS ONE, Vol 12, Iss 1, p e0168198 (2017)

Mitochondria are semi-autonomous organelles that supply energy for cellular biochemistry through oxidative phosphorylation. Within a cell, hundreds of mobile mitochondria undergo fusion and fission events to form a dynamic network. These morphologica

Externí odkaz: https://doaj.org/article/0fc9beca40c34cae88f1b425e6ea5ffc

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XIAP-mediated targeting of endolysosomes to stressed mitochondria occurs in a switch-like, global manner and results in autophagy-independent, sub-organelle level mitochondrial degradation

Autor: Tim Sen Wang, Isabelle Coppens, Nathan Ryan Brady, Anne Hamacher-Brady

Damaged mitochondria can be subject to lysosomal degradation via mitophagy. However, whole-organelle degradation exhibits relatively slow kinetics and thus its impact may be limited in response to acute, fast-acting cellular stress. We previously rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63e14d74e766ba0488e65fa05ecf7843
https://doi.org/10.1101/2023.04.23.538008

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