Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nathan Riccitelli"'
Autor:
Lisa Davis, Nathan Riccitelli, Nancy Valencia, Irene L. Ch’en, Shabnam Tangri, Jennifer L. Brogdon, Creton Kalfoglou, Karen Thudium Mueller, Reinhold Pollner
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss , Pp 535-541 (2021)
Chimeric antigen receptor (CAR)-T cell therapies reprogram T cells to engage and eliminate cancer cells. Patients’ T cells are transduced in vitro using lentiviral or retroviral vectors containing a CAR transgene. Following infusion, CAR-T cells ex
Externí odkaz:
https://doaj.org/article/2b681f0aeb284e3f903d79b38dc6b465
Autor:
Sarah Johnson, Xun Li, Jennifer Bordeaux, Shabnam Tangri, Naveen Dakappagari, Nathan Riccitelli, Nancy Valencia, Ju Young Kim, Nathan Roscoe, James Santos, Justin Santos, Jacob Levy, Deepika Asnani, Tracie Cobb, Angela McIntosh, Reinhold Pollner
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/b1a52b567f874f498552ae4f0e51ec45
Publikováno v:
Cancer Research. 83:3922-3922
Introduction: Genetic information is highly relevant to the classification and risk assessment of myeloid neoplasms, especially myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). Next generation sequencing (NGS) is increasingly used to
Publikováno v:
Cancer Research. 82:3992-3992
Introduction: Single-nucleotide variants (SNVs) are key drivers of both oncogenesis and emergent resistance to targeted therapies. Although high-throughput Identification of SNVs can be achieved with Next Generation Sequencing (NGS) technologies, the
Autor:
Angela McIntosh, Jacob Levy, Sarah Johnson, Reinhold Pollner, Jennifer Bordeaux, Naveen Dakappagari, James Santos, Tracie Cobb, Xun Li, Ju Young Kim, Shabnam Tangri, Nathan Roscoe, Deepika K. Asnani, Nancy Valencia, J. M. Santos, Nathan Riccitelli
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Both proteins (e.g., PD-L1 IHC) and tumor mutation burden (NGS-based) are known to independently predict clinical response to anti-PD-1/PD-L1 therapies. In a meta-analysis of tumor specimens from 8135 patients treated with PD-1/PD-L1 block
Autor:
Lisa Davis, Irene L. Ch’en, Shabnam Tangri, Reinhold Pollner, Creton Kalfoglou, Nancy Valencia, Karen Thudium Mueller, Nathan Riccitelli, Jennifer Brogdon
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 535-541 (2021)
Molecular Therapy: Methods & Clinical Development, Vol 20, Iss, Pp 535-541 (2021)
Chimeric antigen receptor (CAR)-T cell therapies reprogram T cells to engage and eliminate cancer cells. Patients’ T cells are transduced in vitro using lentiviral or retroviral vectors containing a CAR transgene. Following infusion, CAR-T cells ex
Autor:
Nancy Valencia, Eileen Kelly, Justin Wahl, Alexis Kurmis, Reinhold Pollner, Nathan Riccitelli, Christian Laing
Publikováno v:
Cancer Research. 80:1568-1568
Purpose Formalin-fixed, paraffin-embedded (FFPE) tumor tissue, while standard for biological preservation, can significantly impact nucleic-acid quality via degradation and cross-linking. The low quality of FFPE-treated samples, coupled with the pres
Publikováno v:
Cancer Research. 79:2282-2282
Introduction Surgical biopsy or excisional resection is a standard practice in oncology diagnosis that requires a detectable tumor mass and can be highly invasive, limiting its role in the very early detection, as well as ongoing monitoring efforts,
Publikováno v:
Cancer Research. 79:1693-1693
Introduction Myeloid neoplasms are a complex class of disorders characterized by a range of genotypes. Accurate, precise, and rapid identification of these genotypes is crucial in giving the right drug to the right patient at the right time. In this
Autor:
Nathan, Riccitelli, Andrej, Lupták
Publikováno v:
Progress in molecular biology and translational science. 120
The hepatitis delta virus (HDV) ribozymes are catalytic RNAs capable of cleaving their own sugar-phosphate backbone. The HDV virus possesses the ribozymes in both sense and antisense genomic transcripts, where they are essential for processing during