Výsledky vyhledávání - "Nathan R Nelson"

Akademický článek

Daily isoflurane exposure increases barbiturate insensitivity in medullary respiratory and cortical neurons via expression of ε-subunit containing GABA ARs.

Autor: Keith B Hengen, Nathan R Nelson, Kyle M Stang, Stephen M Johnson, Stephanie M Smith, Jyoti J Watters, Gordon S Mitchell, Mary Behan

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0119351 (2015)

The parameters governing GABAA receptor subtype expression patterns are not well understood, although significant shifts in subunit expression may support key physiological events. For example, the respiratory control network in pregnant rats becomes

Externí odkaz: https://doaj.org/article/71c71b3f4c214e4aa68b2b9ba5e379e0

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Akademický článek

Increased GABA(A) receptor ε-subunit expression on ventral respiratory column neurons protects breathing during pregnancy.

Autor: Keith B Hengen, Nathan R Nelson, Kyle M Stang, Stephen M Johnson, Stephanie M Crader, Jyoti J Watters, Gordon S Mitchell, Mary Behan

Publikováno v: PLoS ONE, Vol 7, Iss 1, p e30608 (2012)

GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest. Paradoxically, pregnant animals continue

Externí odkaz: https://doaj.org/article/0f737e175be6440bb5eeb9c7511be33a

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Zebrafish model for congenital myasthenic syndrome reveals mechanisms causal to developmental recovery

Autor: Jason M. Urban, Nathan R. Nelson, Michael Walogorsky, Rebecca Mongeon, Hua Wen, Gail Mandel, Fumihito Ono, Paul Brehm

Publikováno v: Proceedings of the National Academy of Sciences. 109:17711-17716

Mutations in muscle ACh receptors cause slow-channel syndrome (SCS) and Escobar syndrome, two forms of congenital myasthenia. SCS is a dominant disorder with mutations reported for all receptor subunits except γ. Escobar syndrome is distinct, with m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd2a46922847b143a07e96a7e583e954
https://doi.org/10.1073/pnas.1215858109

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Daily isoflurane exposure increases barbiturate insensitivity in medullary respiratory and cortical neurons via expression of ε-subunit containing GABA ARs

Autor: Jyoti J. Watters, Nathan R. Nelson, Gordon S. Mitchell, Keith B. Hengen, Mary Behan, Stephen M. Johnson, Stephanie M.C. Smith, Kyle Michael Stang

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 3, p e0119351 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::526f71c01fc7dc49ef120cbca7dc8230
https://pubmed.ncbi.nlm.nih.gov/25748028

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Zebrafish calls for reinterpretation for the roles of P/Q calcium channels in neuromuscular transmission

Autor: Jeffrey M. Hubbard, Michael W. Linhoff, Julia E. Dallman, Paul Brehm, Nathan R. Nelson, Hua Wen, Gail Mandel, Donald Stensland

A long-held tenet of neuromuscular transmission is that calcium-dependent neurotransmitter release is mediated by N-type calcium channels in frog but P/Q-type channels in mammals. The N-type assignment in frog is based principally on pharmacological

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::310862453fad7749bb4bec598cf82a34
https://europepmc.org/articles/PMC3670695/