Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Nathan P. Rudemiller"'
Autor:
Hsin-I. Huang, Mark L. Jewell, Nourhan Youssef, Min-Nung Huang, Elizabeth R. Hauser, Brian E. Fee, Nathan P. Rudemiller, Jamie R. Privratsky, Junyi J. Zhang, Estefany Y. Reyes, Donghai Wang, Gregory A. Taylor, Michael D. Gunn, Dennis C. Ko, Donald N. Cook, Vidyalakshmi Chandramohan, Steven D. Crowley, Gianna Elena Hammer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and larg
Externí odkaz:
https://doaj.org/article/ec895c03dad444b39ecd52aa071d83d9
Autor:
Xiaohan Lu, Jiandong Zhang, Yi Wen, Jiafa Ren, Robert Griffiths, Nathan P. Rudemiller, Shintaro Ide, Tomokazu Souma, Steven D. Crowley
Publikováno v:
Hypertension
Background: Type 1 angiotensin (AT 1 ) receptors are expressed on immune cells, and we previously found that bone marrow–derived AT 1 receptors protect against Ang (angiotensin) II-induced hypertension. CD11c is expressed on myeloid cells derived f
Autor:
Yi Wen, Jiandong Zhang, Sergei A. Nedospasov, Taylor J. Robinette, Xiaohan Lu, Jamie R. Privratsky, Jiafa Ren, Nathan P. Rudemiller, Steven D. Crowley
Publikováno v:
Am J Physiol Renal Physiol
Nephrotoxic serum nephritis (NTN) models immune-mediated human glomerulonephritis and culminates in kidney inflammation and fibrosis, a process regulated by T lymphocytes. TNF-α is a key proinflammatory cytokine that contributes to diverse forms of
Autor:
Xiaohan Lu, Yi Wen, Steven D. Crowley, Jamie R. Privratsky, Jiafa Ren, Robert Griffiths, Nathan P. Rudemiller
Publikováno v:
Hypertension
FLT3L (Fms-like tyrosine kinase 3 ligand) stimulates the development of classical dendritic cells (DCs). Here we tested the hypothesis that classical DCs drive blood pressure elevation by promoting renal fluid retention. FLT3L-deficient (FLT3L −/
Autor:
Jamie R. Privratsky, Jiafa Ren, Nathan P. Rudemiller, Yi Wen, Sergei A. Nedospasov, Robert I. Griffiths, Bi Cheng Liu, Mukesh K. Jain, Jiandong Zhang, Steven D. Crowley, Xiaohan Lu, Bo Yang
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Polarized macrophage populations can orchestrate both inflammation of the kidney and tissue repair during CKD. Proinflammatory M1 macrophages initiate kidney injury, but mechanisms through which persistent M1-dependent kidney damage culmi
Autor:
Jamie R. Privratsky, Jiafa Ren, Jiandong Zhang, Yi Wen, Xiaohan Lu, Michael D. Gunn, Nathan P. Rudemiller, Steven D. Crowley, Robert I. Griffiths
Publikováno v:
Journal of the American Society of Nephrology. 30:1674-1685
Background Following an acute insult, macrophages regulate renal fibrogenesis through the release of various factors that either encourage the synthesis of extracellular matrix synthesis or the degradation of matrix via endocytosis, proteolysis, or b
Autor:
Nourhan Youssef, Donald N. Cook, Gianna E. Hammer, Vidyalakshmi Chandramohan, Elizabeth R. Hauser, Gregory A. Taylor, Dennis C. Ko, Junyi J. Zhang, Steven D. Crowley, Hsin-I Huang, Nathan P. Rudemiller, Min-Nung Huang, Estefany Y. Reyes, Jamie R. Privratsky, Michael D. Gunn, Brian E. Fee, Donghai Wang, Mark L. Jewell
Intestinal immunity is coordinated by specialized mononuclear phagocyte populations, constituted by a diversity of cell subsets. Although the cell subsets constituting the mononuclear phagocyte network are thought to be similar in both small and larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aee4710a452201e2367b49fd89c7ba61
https://doi.org/10.1101/2021.01.28.428597
https://doi.org/10.1101/2021.01.28.428597
Autor:
Xiaohan Lu, Nathan P. Rudemiller, Yi Wen, Steven D. Crowley, Jamie R. Privratsky, Jiafa Ren, Gianna E. Hammer, Junyi J. Zhang, Robert Griffiths, Jiandong Zhang
Publikováno v:
Hypertension
Activated T lymphocytes that infiltrate blood pressure control organs make a critical contribution to the pathogenesis of hypertension. Dendritic cells act as potent antigen-presenting cells to stimulate prohypertensive T cells. However, the mechanis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::215ef389c6a87adb9f7ae0efd5937a49
https://europepmc.org/articles/PMC7035160/
https://europepmc.org/articles/PMC7035160/
Autor:
Jamie R. Privratsky, Jiandong Zhang, Xiaohan Lu, Michael D. Gunn, Steven D. Crowley, Yen-Rei A. Yu, Qingqing Wei, Nathan P. Rudemiller
Publikováno v:
American Journal of Physiology-Renal Physiology. 315:F682-F691
Acute kidney injury (AKI) is a leading cause of morbidity and mortality. Drug-induced/toxic AKI can be caused by a number of therapeutic agents. Cisplatin is an effective chemotherapeutic agent whose administration is limited by significant nephrotox
Autor:
Yi Wen, Gianna E. Hammer, Nathan P. Rudemiller, Matthew A. Sparks, Jamie R. Privratsky, Jiafa Ren, Xiaohan Lu, Bo Yang, Steven D. Crowley, Robert Griffiths
Publikováno v:
Circ Res
Rationale: The ubiquitin-editing protein A20 in dendritic cells (DCs) suppresses NF-κB (nuclear factor-κB) signaling and constrains DC-mediated T-cell stimulation, but the role of A20 in modulating the hypertensive response requires elucidation. Ob