Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nathan P. Hesemann"'
Autor:
Matthew T. Hirabayashi, Areiss P. Gharabagi, Nathan P. Hesemann, Sandra M. Johnson, Aaron D. Webel, Gregory F. Petroski, Geetha R. Davis
Publikováno v:
Journal of Refractive Surgery. 39:89-94
Purpose: To determine the median spherical aberration (SA) of the cataractous population, how it relates to biometry, and the theoretical effect of different intraocular lens (IOL) platforms. Methods: A retrospective chart review of patients undergoi
Autor:
Suneel Gupta, Michael K. Fink, Duraisamy Kempuraj, Nishant R. Sinha, Lynn M. Martin, Landon M. Keele, Prashant R. Sinha, Elizabeth A. Giuliano, Nathan P. Hesemann, Sudhanshu P. Raikwar, Shyam S. Chaurasia, Rajiv R. Mohan
Publikováno v:
Mol Ther
Previously we found that inhibitor of differentiation 3 (Id3) gene, a transcriptional repressor, efficiently inhibits corneal keratocyte differentiation to myofibroblasts in vitro. This study evaluated the potential of adeno-associated virus 5 (AAV5)
Autor:
Eric Zhang, Suneel Gupta, Evan Olson, Prashant R. Sinha, Nathan P. Hesemann, Fredrick W. Fraunfelder, Rajiv R. Mohan
Publikováno v:
J Ocul Pharmacol Ther
PURPOSE: Topical, local anesthetic eye drops in conjunction with antibiotics are commonly used to reduce ocular pain and treat patients in emergency clinics; however, their effects on corneal healing are poorly understood. This study examined whether
Autor:
Govindaraj Anumanthan, Suneel Gupta, Michael K Fink, Nathan P Hesemann, Douglas K Bowles, Lindsey M McDaniel, Maaz Muhammad, Rajiv R Mohan
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0192145 (2018)
Vision impairment from corneal fibrosis is a common consequence of irregular corneal wound healing after injury. Intermediate-conductance calmodulin/calcium-activated K+ channels 3.1 (KCa3.1) play an important role in cell cycle progression and cellu
Externí odkaz:
https://doaj.org/article/4b4c2c43145342f8b201b4ba70b3f42d
Autor:
Suneel Gupta, Jason T Rodier, Ajay Sharma, Elizabeth A Giuliano, Prashant R Sinha, Nathan P Hesemann, Arkasubhra Ghosh, Rajiv R Mohan
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0172928 (2017)
Corneal scarring is due to aberrant activity of the transforming growth factor β (TGFβ) signaling pathway following traumatic, mechanical, infectious, or surgical injury. Altered TGFβ signaling cascade leads to downstream Smad (Suppressor of mothe
Externí odkaz:
https://doaj.org/article/e25f2c97b4d8484a9257977d7c2f37c4
Autor:
Prashant R. Sinha, Nathan P. Hesemann, Maryam S Muayad, Suneel Gupta, Praveen Balne, Ratnakar Tripathi, Jella A An, Rajiv R. Mohan, Nishant Sinha
Publikováno v:
Translational Vision Science & Technology
Purpose A significant remission of corneal fibrosis and neovascularization in rabbit eye in vivo was observed from a tissue-selective localized adeno-associated virus (AAV)5-Decorin (Dcn) gene therapy. This study sought to investigate 6-month toxicit
Autor:
Nathan P Hesemann, Aaron Warning
Publikováno v:
Journal of cataract and refractive surgery. 46(9)
Autor:
Jason T. Rodier, Shyam S. Chaurasia, Suneel Gupta, Rajiv R. Mohan, Nishant Sinha, Ratnakar Tripathi, Nathan P. Hesemann, Lynn M Martin, Alexandria Hofmann, Michael K Fink, Praveen Balne, Prashant R Sinha, Sabeeh Kamil, James R Landreneau
Publikováno v:
Translational Vision Science & Technology
Purpose This pilot study investigated the in vivo therapeutic potential and tolerability of a multimodal ophthalmic formulation, topical eye drops (TED), for acute mustard gas keratopathy (MGK) using a rabbit model. Methods Twenty New Zealand White r
Autor:
Suneel, Gupta, Lynn M, Martin, Nishant R, Sinha, Kaitlin E, Smith, Prashant R, Sinha, Emilee M, Dailey, Nathan P, Hesemann, Rajiv R, Mohan
Publikováno v:
Molecular vision. 26
Inhibitor of differentiation (Id) proteins are helix-loop-helix (HLH) transcriptional repressors that modulate a range of developmental and cellular processes, including cell differentiation and cell cycle mobilization. ThePrimary human corneal strom
Autor:
Nishant Sinha, Suneel Gupta, Nathan P. Hesemann, Lynn Martin, Shyam S. Chaurasia, Prashant R. Sinha, Rajiv R. Mohan, Jason T. Rodier, Michael K Fink
Publikováno v:
Ann N Y Acad Sci
Acrolein is a highly reactive and volatile unsaturated aldehyde commonly used for producing scores of commercial products. It has been recognized as a chemical weapon since its use during World War I, and more recently, in Syria. Acrolein exposure ca