Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nathan P. Gabrielson"'
Autor:
Nathan P Gabrielson
Publikováno v:
Nanoparticles for Biotherapeutic Delivery (Volume 1). :22-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c735eeda2b21e4e50d097538e8d3e334
https://doi.org/10.4155/fseb2013.13.94
https://doi.org/10.4155/fseb2013.13.94
Autor:
Hua Lu, Rujing Zhang, Nathan P. Gabrielson, Nan Zheng, Lichen Yin, Ziyuan Song, Jianjun Cheng, Kyung Mo Kim, Yao Lin, Haoyu Tang
Publikováno v:
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 7:98-110
The advent of polymeric materials has significantly promoted the development and rapid growth of various technologies in biomedical applications, such as tissue engineering and controlled drug and gene delivery. Water-soluble polypeptides bearing fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a21e4e8014fe5ae7b4c60bc9d69348b9
https://doi.org/10.1002/wnan.1307
https://doi.org/10.1002/wnan.1307
Autor:
Jianjun Cheng, Nan Zheng, Ziyuan Song, Hua Lu, Nathan P. Gabrielson, Haoyu Tang, Liang Ma, Lichen Yin
Publikováno v:
Biomaterials. 35:1302-1314
The application of non-viral gene delivery vectors is often accompanied with the poor correlation between transfection efficiency and the safety profiles of vectors: vectors with high transfection efficiencies often suffer from high toxicities, makin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc19df55128dae61bb4eab3f66b21fd
https://doi.org/10.1016/j.biomaterials.2013.09.090
https://doi.org/10.1016/j.biomaterials.2013.09.090
Autor:
Qiuhao Qu, Kyung Hoon Kim, Jianjun Cheng, Lichen Yin, Catherine Yao, Haoyu Tang, Nathan P. Gabrielson, Fatih M. Uckun, Ziyuan Song, Isthier Chaudhury, Nan Zheng
Publikováno v:
Angewandte Chemie International Edition. 52:5757-5761
Intervention of the inflammation cascade with tumor necrosis factor-α (TNF-α) monoclonal antibodies or receptors represents a major approach in clinical immunotherapy against inflammatory diseases, which however, often suffers from high cost, autoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1889a012066e861e5f365b389ff1fe8a
https://doi.org/10.1002/anie.201209991
https://doi.org/10.1002/anie.201209991
Autor:
Marie Claude Hofmann, Nathan P. Gabrielson, Amit V. Desai, Bhushan Mahadik, Brendan A.C. Harley, Paul J. A. Kenis
Publikováno v:
Small. 9:3076-3081
A hydrogel biochip combining microfluidic mixing and orthogonal supplementation strategies is developed and validated to allow facile generation of libraries of optically transparent 3D culture microenvironments. Live, on-chip tracing of embryonic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c33eeff8a2f80eb9e0592042621b26
https://doi.org/10.1002/smll.201203030
https://doi.org/10.1002/smll.201203030
Autor:
Kyung Hoon Kim, Haoyu Tang, Lichen Yin, Jianjun Cheng, Ziyuan Song, Nathan P. Gabrielson, Hua Lu, Nan Zheng
Publikováno v:
Biomaterials. 34:2340-2349
Poly(γ-4-((2-(piperidin-1-yl)ethyl)aminomethyl)-benzyl-l-glutamate) (PPABLG), a cationic helical polypeptide, has been recently developed by us as an effective non-viral gene delivery vector. In attempts to elucidate the effect of molecular architec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4123f2344ff6d1884c3dcc15bcaa322
https://doi.org/10.1016/j.biomaterials.2012.11.064
https://doi.org/10.1016/j.biomaterials.2012.11.064
Publikováno v:
Advanced Materials. 25:3063-3070
Supramolecular self-assembled nanocomplexes (SSANs) capable of mannose receptor-mediated endocytosis and permeable to cellular and endosomal membranes are developed via the assembly of multiple rationally designed, function-specific materials. As a u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9910993a9067a96fab19cf3c256a6a97
https://doi.org/10.1002/adma.201205088
https://doi.org/10.1002/adma.201205088
Publikováno v:
Molecular Therapy. 20(8):1599-1609
Cell-penetrating peptides (CPPs) are routinely used for intracellular delivery of a variety of cargo, including drugs, genes, and short interfering RNA (siRNA). Most CPPs are active only upon exposure to acidic environments inside of late endosomes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecfed699fa9dd1eb1ce3b4c0e8bc6bde
Publikováno v:
Pharmaceutical Research. 29:500-510
Crosslinked, degradable derivatives of low-molecular-weight polyethylenimine (PEI) are relatively efficient and non-cytotoxic gene delivery agents. To further investigate these promising materials, a new synthetic approach was developed using a poly(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928d7c8b140f2cd0f66c7dc73ad6e081
https://doi.org/10.1007/s11095-011-0576-5
https://doi.org/10.1007/s11095-011-0576-5
Publikováno v:
Macromolecules. 44:6237-6240
Introducing various pendant functional groups and building blocks of interest to polypeptides in a highly efficient, controlled manner is crucial to access polypeptide materials with desired structures and functions. In this study, we synthesized γ-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1642a78b7e0722f9513d4854d6f15459
https://doi.org/10.1021/ma201164n
https://doi.org/10.1021/ma201164n