Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Nathan P. Clark"'
Autor:
Alfonso J. Tafur, Nathan P. Clark, Alex C. Spyropoulos, Na Li, Eric Kaplovitch, Kira MacDougall, Sam Schulman, Joseph A. Caprini, James Douketis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 19 (2020)
Background In the PAUSE (Perioperative Anticoagulant Use for Surgery Evaluation) Study, a simple, standardized, perioperative interruption strategy was provided for patients with nonvalvular atrial fibrillation taking direct oral anticoagulants (DOAC
Externí odkaz:
https://doaj.org/article/7de21de30c804f2ea1f38fd8e9c77c41
Autor:
Kira MacDougall, James D. Douketis, Na Li, Nathan P. Clark, Alfonso Tafur, Julien D'Astous, Joanne Duncan, Sam Schulman, Alex C. Spyropoulos
Publikováno v:
TH Open, Vol 04, Iss 03, Pp e255-e262 (2020)
Introduction The Perioperative Anticoagulation Use for Surgery Evaluation (PAUSE) Study assessed a standardized perioperative management strategy in patients with atrial fibrillation who were taking a direct oral anticoagulant (DOAC) and required an
Externí odkaz:
https://doaj.org/article/4d1d26a693bc4e7e859f3f38a1187fca
Publikováno v:
eLife, Vol 12 (2024)
Co-functional proteins tend to have rates of evolution that covary over time. This correlation between evolutionary rates can be measured over the branches of a phylogenetic tree through methods such as evolutionary rate covariation (ERC), and then u
Externí odkaz:
https://doaj.org/article/5f2d164f84f6462f93e2138baffd2718
Autor:
Emma Campbell, Ellie Macey, Chris Shine, Vahé Nafilyan, Nathan Cadogan Clark, Piotr Pawelek, Isobel Ward, Andrew Hughes, Veena Raleigh, Amitava Banerjee, Katie Finning
Publikováno v:
EClinicalMedicine, Vol 65, Iss , Pp 102275- (2023)
Summary: Background: Hypertension is a leading cause of morbidity and mortality worldwide, yet a substantial proportion of cases are undiagnosed. Understanding the scale of undiagnosed hypertension and identifying groups most at risk is important to
Externí odkaz:
https://doaj.org/article/9be0361b9b1747c5b8546ef10481bdb0
Autor:
Jen-Wei Huang, Ananya Acharya, Angelo Taglialatela, Tarun S. Nambiar, Raquel Cuella-Martin, Giuseppe Leuzzi, Samuel B. Hayward, Sarah A. Joseph, Gregory J. Brunette, Roopesh Anand, Rajesh K. Soni, Nathan L. Clark, Kara A. Bernstein, Petr Cejka, Alberto Ciccia
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Homologous recombination (HR) is an essential DNA repair pathway for genomic stability. Here the authors show that C17orf53/MCM8IP, an OB-fold containing protein, promotes HR through direct binding and activation of the MCM8-9 helicase complex.
Externí odkaz:
https://doaj.org/article/86fa91a9e36c4bd1bfde918a8bfb93ee
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractBaker’s yeast contains a large number of duplicated genes; some function redundantly, whereas others have more specialized roles. We used the MLH family of DNA mismatch repair (MMR) proteins as a model to better understand the steps that le
Externí odkaz:
https://doaj.org/article/f4e301790a1f4db8a9548b50e7079f60
Autor:
Lauren Cline, Erika Marie G. Generoso, Nicholas D’Apice, Sara K. Dellinger, Amber Tovey, Nathan P. Clark, Fang Nui, Rita Hui, Stephanie A. Hale, Tanya Ramsey, Kimi Pontoppidan, Hasmig Ekmekdjian, Kristen Fink, Daniel M. Witt, Mark A. Crowther, Thomas Delate
Publikováno v:
Journal of Thrombosis and Thrombolysis. 55:355-364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06955df237c87323a6be0ad9158005e2
https://doi.org/10.1007/s11239-022-02758-7
https://doi.org/10.1007/s11239-022-02758-7
Autor:
Qanber Raza, Jae Young Choi, Yang Li, Roisin M O'Dowd, Simon C Watkins, Maria Chikina, Yang Hong, Nathan L Clark, Adam V Kwiatkowski
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1007720 (2019)
The adherens junction couples the actin cytoskeletons of neighboring cells to provide the foundation for multicellular organization. The core of the adherens junction is the cadherin-catenin complex that arose early in the evolution of multicellulari
Externí odkaz:
https://doaj.org/article/b94bf99c5b2f4a23a06bbde21f244b06
Autor:
Geoffrey D Barnes, Allison Burnett, Arthur Allen, Jack Ansell, Marilyn Blumenstein, Nathan P Clark, Mark Crowther, William E Dager, Steven B. Deitelzweig, Stacy Ellsworth, David Garcia, Scott Kaatz, Leslie Raffini, Anita Rajasekhar, Andrea Van Beek, Tracy Minichiello
Publikováno v:
Journal of Thrombosis and Thrombolysis. 54:197-210
Thromboembolism is a common and deadly consequence of COVID-19 infection for hospitalized patients. Based on clinical evidence pre-dating the COVID-19 pandemic and early observational reports, expert consensus and guidance documents have strongly enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2d3d8ae4e1ebcc88697c685382bd36
https://doi.org/10.1007/s11239-022-02643-3
https://doi.org/10.1007/s11239-022-02643-3
Autor:
Lauren, Cline, Erika Marie G, Generoso, Nicholas, D'Apice, Sara K, Dellinger, Amber, Tovey, Nathan P, Clark, Fang, Nui, Rita, Hui, Stephanie A, Hale, Tanya, Ramsey, Kimi, Pontoppidan, Hasmig, Ekmekdjian, Kristen, Fink, Daniel M, Witt, Mark A, Crowther, Thomas, Delate
Publikováno v:
Journal of thrombosis and thrombolysis.
The few studies that compared direct oral anticoagulants (DOAC) vs. warfarin in the setting of advanced renal insufficiency have focused on patients with atrial fibrillation. The purpose of this observational, matched, cohort study of patients was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f017d595a3d2a3673352526500049ca
https://pubmed.ncbi.nlm.nih.gov/36564588
https://pubmed.ncbi.nlm.nih.gov/36564588