Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nathan O. Surles"'
Autor:
Sarah L. Huszar, Nathan O. Surles, Janet Clark, Lihang Yao, James C. Barrow, John J. Renger, Sean M. Smith, Pete H. Hutson, Shannon Nguyen, Jason M. Uslaner, Richard M. Hinchliffe, Rashida Pachmerhiwala, Victor N. Uebele, Joshua D. Vardigan
Publikováno v:
Neuropharmacology. 62(3)
T-type calcium channels are important in burst firing and expressed in brain regions implicated in schizophrenia. Therefore, we examined the effects of novel selective T-type calcium channel antagonists in preclinical assays predictive of antipsychot
Autor:
Nathan O. Surles, Nancy A. Sachs, Jason M. Uslaner, Tim Sparey, Monika Kandebo, Mary Beth Young, Richard M. Hinchliffe, Caitlyn H. McNaughton, Brian A. Jones, Shankar Venkatraman, Marlene A. Jacobson, Peter H. Hutson, Lihang Yao, Sean M. Smith, Sarah L. Huszar, Danette Pascarella, Nicholas J. Brandon, Chadwick M. Mullins
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 328(3)
Multiple studies indicate that N-methyl-D-aspartate (NMDA) receptor hypofunction underlies some of the deficits associated with schizophrenia. One approach for improving NMDA receptor function is to enhance occupancy of the glycine modulatory site on