Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Nathan O Siemers"'
Autor:
Nathan O Siemers, James L Holloway, Han Chang, Scott D Chasalow, Petra B Ross-MacDonald, Charles F Voliva, Joseph D Szustakowski
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0179726 (2017)
Therapeutic options for the treatment of an increasing variety of cancers have been expanded by the introduction of a new class of drugs, commonly referred to as checkpoint blocking agents, that target the host immune system to positively modulate an
Externí odkaz:
https://doaj.org/article/97ededee36164e1f82e0b2082605a781
Autor:
Han Chang, Donald G Jackson, Paul S Kayne, Petra B Ross-Macdonald, Rolf-Peter Ryseck, Nathan O Siemers
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21097 (2011)
It is well established that genomic alterations play an essential role in oncogenesis, disease progression, and response of tumors to therapeutic intervention. The advances of next-generation sequencing technologies (NGS) provide unprecedented capabi
Externí odkaz:
https://doaj.org/article/a54a7ce4fad445b5815a366415849757
Autor:
Rui-Ru Ji, Heshani de Silva, Yisheng Jin, Robert E Bruccoleri, Jian Cao, Aiqing He, Wenjun Huang, Paul S Kayne, Isaac M Neuhaus, Karl-Heinz Ott, Becky Penhallow, Mark I Cockett, Michael G Neubauer, Nathan O Siemers, Petra Ross-Macdonald
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 9, p e1000512 (2009)
The dose response curve is the gold standard for measuring the effect of a drug treatment, but is rarely used in genomic scale transcriptional profiling due to perceived obstacles of cost and analysis. One barrier to examining transcriptional dose re
Externí odkaz:
https://doaj.org/article/2200014703f348538cb5cd6ad646b99a
Autor:
Peter M. Szabo, Amir Vajdi, Namit Kumar, Michael Y. Tolstorukov, Benjamin J. Chen, Robin Edwards, Keith L. Ligon, Scott D. Chasalow, Kin-Hoe Chow, Aniket Shetty, Mohan Bolisetty, James L. Holloway, Ryan Golhar, Brian A. Kidd, Philip Ansumana Hull, Jeff Houser, Logan Vlach, Nathan O. Siemers, Saurabh Saha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis, and drug resistance. However, the mechanisms underlying these associations are largely unknown. We studied several tumor types to identify the source
Externí odkaz:
https://doaj.org/article/866f80112fea46098f67f5660d88664d
Autor:
Ruth Y. Lan, Renu Jain, Jack Lohre, Sandra V. Hatcher, Kai Lu, Sharmila Sambanthamoorthy, Jeff Houser, Logan M. Vlach, Alan J. Korman, Tim W. Sproul, Mark Selby, Priti B. Singh, Nathan O. Siemers, Paul B. Mesko, Bryan R. McDonald, Joseph R. Campbell
Figure S5 shows human splenic and skin expressions of CCR8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea910d6113b477ee28be3a4efdb700d
https://doi.org/10.1158/0008-5472.22430338
https://doi.org/10.1158/0008-5472.22430338
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Supplementary Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9522537b32eed18f18dcf3a1c1097324
https://doi.org/10.1158/1078-0432.22481259.v1
https://doi.org/10.1158/1078-0432.22481259.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Purpose:In advanced gastric cancer/gastroesophageal junction cancer (GC/GEJC), there is a need to identify biomarkers of response to therapies, such as immune checkpoint inhibitors.Patients and Methods:In post hoc exploratory analyses from CheckMate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87927031a61e65f5923467f0c87959b
https://doi.org/10.1158/1078-0432.c.6530646.v1
https://doi.org/10.1158/1078-0432.c.6530646.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Gene expression levels by cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f09d1681d4fbca853b5013a2d27119
https://doi.org/10.1158/1078-0432.22481250.v1
https://doi.org/10.1158/1078-0432.22481250.v1
Autor:
Ruth Y. Lan, Renu Jain, Jack Lohre, Sandra V. Hatcher, Kai Lu, Sharmila Sambanthamoorthy, Jeff Houser, Logan M. Vlach, Alan J. Korman, Tim W. Sproul, Mark Selby, Priti B. Singh, Nathan O. Siemers, Paul B. Mesko, Bryan R. McDonald, Joseph R. Campbell
Supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e367b24ef957365c6ae9ca9650d11e
https://doi.org/10.1158/0008-5472.22430326.v1
https://doi.org/10.1158/0008-5472.22430326.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Corresponding % TC and CPS with response and OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384273ce28f5a506719d5a6b3973d90c
https://doi.org/10.1158/1078-0432.22481253
https://doi.org/10.1158/1078-0432.22481253