Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Nathan O Siemers"'
Autor:
Peter M. Szabo, Amir Vajdi, Namit Kumar, Michael Y. Tolstorukov, Benjamin J. Chen, Robin Edwards, Keith L. Ligon, Scott D. Chasalow, Kin-Hoe Chow, Aniket Shetty, Mohan Bolisetty, James L. Holloway, Ryan Golhar, Brian A. Kidd, Philip Ansumana Hull, Jeff Houser, Logan Vlach, Nathan O. Siemers, Saurabh Saha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Epithelial-to-mesenchymal transition (EMT) is associated with tumor initiation, metastasis, and drug resistance. However, the mechanisms underlying these associations are largely unknown. We studied several tumor types to identify the source
Externí odkaz:
https://doaj.org/article/866f80112fea46098f67f5660d88664d
Autor:
Ruth Y. Lan, Renu Jain, Jack Lohre, Sandra V. Hatcher, Kai Lu, Sharmila Sambanthamoorthy, Jeff Houser, Logan M. Vlach, Alan J. Korman, Tim W. Sproul, Mark Selby, Priti B. Singh, Nathan O. Siemers, Paul B. Mesko, Bryan R. McDonald, Joseph R. Campbell
Figure S5 shows human splenic and skin expressions of CCR8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bea910d6113b477ee28be3a4efdb700d
https://doi.org/10.1158/0008-5472.22430338
https://doi.org/10.1158/0008-5472.22430338
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Supplementary Material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9522537b32eed18f18dcf3a1c1097324
https://doi.org/10.1158/1078-0432.22481259.v1
https://doi.org/10.1158/1078-0432.22481259.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Purpose:In advanced gastric cancer/gastroesophageal junction cancer (GC/GEJC), there is a need to identify biomarkers of response to therapies, such as immune checkpoint inhibitors.Patients and Methods:In post hoc exploratory analyses from CheckMate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e87927031a61e65f5923467f0c87959b
https://doi.org/10.1158/1078-0432.c.6530646.v1
https://doi.org/10.1158/1078-0432.c.6530646.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Gene expression levels by cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80f09d1681d4fbca853b5013a2d27119
https://doi.org/10.1158/1078-0432.22481250.v1
https://doi.org/10.1158/1078-0432.22481250.v1
Autor:
Ruth Y. Lan, Renu Jain, Jack Lohre, Sandra V. Hatcher, Kai Lu, Sharmila Sambanthamoorthy, Jeff Houser, Logan M. Vlach, Alan J. Korman, Tim W. Sproul, Mark Selby, Priti B. Singh, Nathan O. Siemers, Paul B. Mesko, Bryan R. McDonald, Joseph R. Campbell
Supplemental materials and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91e367b24ef957365c6ae9ca9650d11e
https://doi.org/10.1158/0008-5472.22430326.v1
https://doi.org/10.1158/0008-5472.22430326.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Corresponding % TC and CPS with response and OS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::384273ce28f5a506719d5a6b3973d90c
https://doi.org/10.1158/1078-0432.22481253
https://doi.org/10.1158/1078-0432.22481253
Autor:
Ruth Y. Lan, Renu Jain, Jack Lohre, Sandra V. Hatcher, Kai Lu, Sharmila Sambanthamoorthy, Jeff Houser, Logan M. Vlach, Alan J. Korman, Tim W. Sproul, Mark Selby, Priti B. Singh, Nathan O. Siemers, Paul B. Mesko, Bryan R. McDonald, Joseph R. Campbell
FOXP3+ regulatory T cells (Treg) play a critical role in mediating tolerance to self-antigens and can repress antitumor immunity through multiple mechanisms. Therefore, targeted depletion of tumor-resident Tregs is warranted to promote effective anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31e7ef976adf7153577afb0d10288c03
https://doi.org/10.1158/0008-5472.c.6513598.v1
https://doi.org/10.1158/0008-5472.c.6513598.v1
Autor:
Zachary Boyd, Ian Chau, Filippo de Braud, Thomas R. Jeffry Evans, Johanna Bendell, Padmanee Sharma, Patrick A. Ott, Yelena Janjigian, Peter M. Szabo, Christopher Harbison, Teresa Sanchez, Han Chang, Dimple Pandya, Nathan O. Siemers, Ming Lei
Additional details on CPS scoring done by Agilent-certified pathologists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f02e47cbe52ecb440674aed62678056
https://doi.org/10.1158/1078-0432.22481256.v1
https://doi.org/10.1158/1078-0432.22481256.v1
Autor:
Paul B Mesko, Sandra V. Hatcher, Priti B. Singh, Renu Jain, Sharmila Sambanthamoorthy, Joseph R Campbell, Tim Sproul, Nathan O. Siemers, Jack Lohre, Alan J. Korman, Logan M Vlach, Ruth Y. Lan, Mark J. Selby, Bryan McDonald, Jeff Houser, Kai Lu
Publikováno v:
Cancer Research. 81:2983-2994
FOXP3+ regulatory T cells (Treg) play a critical role in mediating tolerance to self-antigens and can repress antitumor immunity through multiple mechanisms. Therefore, targeted depletion of tumor-resident Tregs is warranted to promote effective anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91bc0f0eeb5d72b9c82e63ab561ca526
https://doi.org/10.1158/0008-5472.can-20-3585
https://doi.org/10.1158/0008-5472.can-20-3585