Výsledky vyhledávání - "Nathan McMahon"

Quantitative imaging of tyrosine kinase inhibitor distribution in live cells and tissues

Autor: Lei G. Wang, Antonio Montaño, Allison Solanki, Nathan McMahon, Kenneth M. Tichauer, Kimberley S. Samkoe, Summer L. Gibbs

Publikováno v: Frontiers in Biological Detection: From Nanosensors to Systems XIV.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cef69a5d68df84e7c487a95b01f418c3
https://doi.org/10.1117/12.2612233

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Intracellular paired agent imaging enables improved evaluation of tyrosine kinase inhibitor target engagement

Autor: Allison, Solanki, Lei, Wang, Jesse, Korber, Nathan, McMahon, Kenneth, Tichauer, Kimberley S, Samkoe, Summer L, Gibbs

Targeting the aberrant epidermal growth factor receptor (EGFR) signaling pathway is an attractive choice for many cancers (e.g., non-small cell lung carcinoma (NSCLC) and head and neck squamous cell carcinoma (HNSCC)). Despite the development of prom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::04264c40e15aafabbb0aa036e7936512
https://europepmc.org/articles/PMC7155938/

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An anti-IL-13 antibody reverses epithelial-mesenchymal transition biomarkers in eosinophilic esophagitis: Phase 2 trial results

Autor: Ryan Deaton, Sarah Harris, Cristian Rodriguez, Steven Y. Hua, Ikuo Hirano, Margaret H. Collins, Evan S. Dellon, Peter H. Gann, Nathan McMahon

Publikováno v: The Journal of allergy and clinical immunology. 146(2)

Background Fibrostenosis, the most serious eosinophilic esophagitis (EoE) complication, is mediated by epithelial-mesenchymal transition (EMT). Transitioned cells contribute to pathogenesis by overproducing extracellular matrix. Objective Our aim was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8042c8d8f7a1671e575718be74b37070
https://pubmed.ncbi.nlm.nih.gov/32407835

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Markers of Esophageal Epithelial-Mesenchymal Transition Are Significantly Reduced in Active Eosinophilic Esophagitis Following 16 Weeks of Treatment With RPC4046, an Anti-Interleukin-13 Monoclonal Antibody

Autor: Amy Woo, Evan S. Dellon, Margaret H. Collins, Peter H. Gann, Richard Aranda, Mahinda Karunaratne, Allan Olson, Ikuo Hirano, Michael Grimm, Ryan Deaton, Gregory J. Opiteck, Nathan McMahon

Publikováno v: Journal of Allergy and Clinical Immunology. 143:AB135

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b1e6a16989c5fbe10c684a71ba82bff8
https://doi.org/10.1016/j.jaci.2018.12.409

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Sa1111 - Markers of Esophageal Epithelial-Mesenchymal Transition (Emt) are Significantly Reduced in Active Eosinophilic Esophagitis Following 16 Weeks of Treatment with Rpc4046, an Anti-Interleukin-13 Monoclonal Antibody

Autor: Ikuo Hirano, Amy Woo, Richard Aranda, Nathan McMahon, Gregory J. Opiteck, Ryan Deaton, Evan S. Dellon, Margaret H. Collins, Peter H. Gann, Allan Olson

Publikováno v: Gastroenterology. 154:S-243

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dabf3885b6a456cfd33a27500447e819
https://doi.org/10.1016/s0016-5085(18)31192-2

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Akademický článek

Paired-Agent Fluorescence Molecular Imaging of Sentinel Lymph Nodes Using Indocyanine Green as a Control Agent for Antibody-Based Targeted Agents.

Autor: Chengyue Li, Xiaochun Xu, Nathan McMahon, Omar Alhaj Ibrahim, Husain A. Sattar, Kenneth M. Tichauer

Publikováno v: Contrast Media & Molecular Imaging; 1/3/2019, p1-13, 13p, 1 Color Photograph, 1 Diagram, 5 Graphs

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