Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nathan M. Samskey"'
Autor:
Nathan M. Samskey, Palmer Taylor, Zoran Radić, Arnold Garcia, Yadira Sepulveda, Rakesh K. Sit, K. Barry Sharpless, Jeremiah D. Momper, Yan Jye Shyong
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 378:315-321
Inhibition of acetylcholinesterase (AChE) by certain organophosphates (OPs) can be life-threatening and requires reactivating antidote accessibility to the peripheral and central nervous systems to reverse symptoms and enhance survival parameters. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91471633449ad7f8cc9ca68c86ba077
https://doi.org/10.1124/jpet.121.000715
https://doi.org/10.1124/jpet.121.000715
Autor:
K. Barry Sharpless, Zoran Radić, William Fenical, Gisela Andrea Camacho-Hernandez, Yan Jye Shyong, Palmer Taylor, Zrinka Kovarik, Nathan M. Samskey, Kwok Yiu Ho
We detail here distinctive departures from lead classical cholinesterase re-activators, the pyridinium aldoximes, to achieve rapid CNS penetration and reactivation of AChE in the CNS (brain and spinal cord). Such reactivation is consistent with these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09ef383abc5abeea87394290920645f8
https://www.bib.irb.hr/1196012
https://www.bib.irb.hr/1196012
