High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

Autor: Graham Simmons, Vanessa Brès, Kai Lu, Nathan M. Liss, Donald J. Brambilla, Kyle R. Ryff, Roberta Bruhn, Edwin Velez, Derrek Ocampo, Jeffrey M. Linnen, Gerardo Latoni, Lyle R. Petersen, Phillip Williamson, Edward L. Murphy

Publikováno v: Emerging Infectious Diseases, Vol 22, Iss 7, Pp 1221-1228 (2016)

Chikungunya virus (CHIKV) caused large epidemics throughout the Caribbean in 2014. We conducted nucleic acid amplification testing (NAAT) for CHIKV RNA (n = 29,695) and serologic testing for IgG against CHIKV (n = 1,232) in archived blood donor sampl

Externí odkaz: https://doaj.org/article/8844e7b65b0f43cf85097d41e86901ac

High Incidence of Chikungunya Virus and Frequency of Viremic Blood Donations during Epidemic, Puerto Rico, USA, 2014

Autor: Nathan M. Liss, Vanessa Brès, Phillip C. Williamson, Kai Lu, Jeffrey M. Linnen, Graham Simmons, Roberta Bruhn, Derrek Ocampo, Kyle R. Ryff, Gerardo Latoni, Donald Brambilla, Michael P. Busch, Lyle R. Petersen, Edwin Velez

Publikováno v: Emerging Infectious Diseases, Vol 22, Iss 7, Pp 1221-1228 (2016)
Emerging Infectious Diseases

Deaths were rarely observed, but newborns and other vulnerable populations are at risk for severe complications.
Chikungunya virus (CHIKV) caused large epidemics throughout the Caribbean in 2014. We conducted nucleic acid amplification testing (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2843978f81978a3dabd9492fa60e06b
https://doi.org/10.3201/eid2207.160116

A humanized IgG but not IgM antibody is effective in prophylaxis and therapy of yellow fever infection in an AG129/17D-204 peripheral challenge mouse model

Autor: Jacob J. Schlesinger, Nathan M. Liss, Joseph Piper, Carol D. Blair, Brett A. Thibodeaux, John T. Roehrig, Nina C. Garbino

Publikováno v: Antiviral Research. 94:1-8

Yellow fever virus (YFV), a member of the genus Flavivirus, is a mosquito-borne virus found in tropical regions of Africa and South America that causes severe hepatic disease and death in humans. Despite the availability of effective vaccines, YFV is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1298b4a5251b5d9aec0394e3ac45aee
https://doi.org/10.1016/j.antiviral.2012.02.001

A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease

Autor: Kristen M. Kahle, Andreas Suhrbier, Suganya Selvarajah, Joy Gardner, Giada Rossini, Kai Lu, David Avram Sanders, Graham Simmons, Rachel H. Fong, Trevor Barnes, Nicole R. Sexton, David F. Tucker, Beatriz Salvador, Vittorio Sambri, Kimberly-Anne Mattia, Joseph Rucker, Alain Michault, Nathan M. Liss, Xiangdong Zhou, Benjamin J. Doranz, Marcus O. Muench, Manu Mabila

Publikováno v: PLoS Neglected Tropical Diseases
Department of Biological Sciences Faculty Publications
PLoS Neglected Tropical Diseases, Vol 7, Iss 9, p e2423 (2013)

The mosquito-borne alphavirus, chikungunya virus (CHIKV), has recently reemerged, producing the largest epidemic ever recorded for this virus, with up to 6.5 million cases of acute and chronic rheumatic disease. There are currently no licensed vaccin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575563a314c14adfa17a5e47d6d6d71c

A small animal peripheral challenge model of yellow fever using interferon-receptor deficient mice and the 17D-204 vaccine strain

Autor: John T. Roehrig, Brett A. Thibodeaux, Joseph Piper, Carol D. Blair, Nina C. Garbino, Nathan M. Liss

Publikováno v: Vaccine. 30(21)

Yellow fever virus (YFV), a member of the genus Flavivirus, is a mosquito-borne pathogen that requires wild-type (wt), virulent strains to be handled at biosafety level (BSL) 3, with HEPA-filtration of room air exhaust (BSL3+). YFV is found in tropic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ff12cc8ff0fd43824adb4bcebd5836b
https://pubmed.ncbi.nlm.nih.gov/22425792