Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nathan M. Fastman"'
Autor:
Nathan M. Fastman, Yuxi Liu, Vyas Ramanan, Hanne Merritt, Eileen Ambing, Anna A. DePaoli-Roach, Peter J. Roach, Thomas D. Hurley, Kevin T. Mellem, Julie C. Ullman, Eric Green, David Morgans, Jr., Christos Tzitzilonis
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111041- (2022)
Summary: Glycogen is the primary energy reserve in mammals, and dysregulation of glycogen metabolism can result in glycogen storage diseases (GSDs). In muscle, glycogen synthesis is initiated by the enzymes glycogenin-1 (GYG1), which seeds the molecu
Externí odkaz:
https://doaj.org/article/48c6548bd0854270915cfc7f6ac2d38f
Autor:
Chao Fan, Benjamin J. Orlando, Melissa G. Chambers, Maofu Liao, Minrui Fan, Nathan M. Fastman, Liang Feng, Xiaofang Xu, Yan Xu, Jinru Zhang, Kay Perry
Publikováno v:
Nature. 559:575-579
Mitochondrial calcium uptake plays critical roles in regulating ATP production, intracellular calcium signaling, and cell death. This uptake is mediated by a highly selective calcium channel called the mitochondrial calcium uniporter. Here, we determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91e5e42519b97fd4137003670ca485c
https://doi.org/10.1038/s41586-018-0330-9
https://doi.org/10.1038/s41586-018-0330-9
Ndm, a coiled-coil domain protein that suppresses macropinocytosis and has effects on cell migration
Publikováno v:
Molecular Biology of the Cell
The Ndm protein colocalizes with coronin and is necessary for formation of rounded lamellipodia and cell spreading. Ndm-null cells show increased endocytosis and lamellipodia that break up into endocytic cups. The protein functions to limit endocytos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c593ccc5fb2d71eb27b8ae6d1795720a
https://doi.org/10.1091/mbc.e12-05-0392
https://doi.org/10.1091/mbc.e12-05-0392
Publikováno v:
Biophysical Journal. 114:207a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9caa2aac604bb99c3b4b82d813772a47
https://doi.org/10.1016/j.bpj.2017.11.1160
https://doi.org/10.1016/j.bpj.2017.11.1160
Autor:
Nathan M. Fastman, AJ Venkatakrishnan, Ron O. Dror, Liang Feng, Naomi R. Latorraca, Wolf B. Frommer
Publikováno v:
Cell. 169:96-107.e12
Summary Transporters shuttle molecules across cell membranes by alternating among distinct conformational states. Fundamental questions remain about how transporters transition between states and how such structural rearrangements regulate substrate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a469758d6bd63a998c82e672036f0b
https://doi.org/10.1016/j.cell.2017.03.010
https://doi.org/10.1016/j.cell.2017.03.010
Publikováno v:
Eukaryotic cell. 11(4)
The ampA gene plays a role in Dictyostelium discoideum cell migration. Loss of ampA function results in reduced ability of growing cells to migrate to folic acid and causes small plaques on bacterial lawns, while overexpression of AmpA results in a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3ba6c6557345ed1644b5abff69cd21
https://pubmed.ncbi.nlm.nih.gov/22307974
https://pubmed.ncbi.nlm.nih.gov/22307974