Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Nathan M Holmes"'
Publikováno v:
eLife, Vol 13 (2024)
How is new information organized in memory? According to latent state theories, this is determined by the level of surprise, or prediction error, generated by the new information: a small prediction error leads to the updating of existing memory, lar
Externí odkaz:
https://doaj.org/article/ffb2d2c4319e46938bddd0ace2b014da
Publikováno v:
eLife, Vol 8 (2019)
How does a stimulus never associated with danger become frightening? The present study addressed this question using a sensory preconditioning task with rats. In this task, rats integrate a sound-light memory formed in stage 1 with a light-danger mem
Externí odkaz:
https://doaj.org/article/da68e64155044d8ab241715f6263af07
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93506 (2014)
BackgroundObesity is associated with excessive consumption of palatable, energy dense foods. The present study used an animal model to examine feeding patterns during exposure to and withdrawal from these foods.MethodsMale Sprague Dawley rats were ex
Externí odkaz:
https://doaj.org/article/78278ea21db04b0ab9c17dad2ba28bf5
Publikováno v:
Neuroscience & Biobehavioral Reviews. 132:1197-1204
Sensory preconditioning protocols can be used to assess how the brain integrates memories that share common features. In these protocols, animals are first exposed to pairings of two relatively innocuous stimuli, S2 and S1 (stage 1), and then to pair
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e02062d8fee7720c708282f32aa676d
https://doi.org/10.1016/j.neubiorev.2021.10.032
https://doi.org/10.1016/j.neubiorev.2021.10.032
Autor:
Jessica Leake, Dana M. Leidl, Belinda P. P. Lay, Justine P. Fam, Madeleine C. Giles, Omar A. Qureshi, R. Frederick Westbrook, Nathan M. Holmes
Activity in the basolateral amygdala complex (BLA) is needed to encode fears acquired through contact with both innate sources of danger (i.e., things that are painful) and learned sources of danger (e.g., being threatened with a gun). However, withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a497369af8966b5fa9a811bccf988e09
https://doi.org/10.1101/2022.12.05.519226
https://doi.org/10.1101/2022.12.05.519226
It is widely accepted that fear memories are consolidated through protein synthesis-dependent changes in the basolateral amygdala complex (BLA). However, recent studies show that protein synthesis isnotrequired to consolidate the memory of a new dang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4a181717cb3182027f66606a7ffc87
https://doi.org/10.1101/2022.12.03.518947
https://doi.org/10.1101/2022.12.03.518947
Autor:
Omar A. Qureshi, Jessica Leake, Andrew J. Delaney, Simon Killcross, R. Frederick Westbrook, Nathan M. Holmes
This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6885e06de7881f2bed2d78324ea16df5
https://doi.org/10.1101/2022.12.02.518124
https://doi.org/10.1101/2022.12.02.518124
Publikováno v:
Journal of Experimental Psychology: Animal Learning and Cognition. 47:211-215
Rescorla (2001) used the compound test procedure to compare associative changes to cues located at different points on a performance scale. He found that associative changes to cues conditioned in compound are not necessarily equal, as predicted by c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18b95e84021befcc47ce30b696157e88
https://doi.org/10.1037/xan0000271
https://doi.org/10.1037/xan0000271
Publikováno v:
Journal of Experimental Psychology: Animal Learning and Cognition. 47:91-103
The Hall-Rodriguez (Hall & Rodriguez, 2010) theory predicts that latent inhibition can be facilitated when a target stimulus is preexposed in compound with a second, nontarget stimulus: specifically, latent inhibition will be facilitated when the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875f01a7a0a560ed7c7688d12188571c
https://doi.org/10.1037/xan0000289
https://doi.org/10.1037/xan0000289
Autor:
Travis P. Todd, Nathan M. Holmes
Publikováno v:
Frontiers in behavioral neuroscience. 16
In standard (first-order) Pavlovian conditioning protocols, pairings of an initially neutral conditioned stimulus (CS) and a biologically significant unconditioned stimulus (US) result in the formation of a CS-US association. The strength of this ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3fa503a1c2fef33cf36b510351764d
https://pubmed.ncbi.nlm.nih.gov/36311862
https://pubmed.ncbi.nlm.nih.gov/36311862