Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nathan L. McKnight"'
Publikováno v:
Experimental Cell Research. 292:265-273
Mechanical stimulation has been proposed as a fundamental determinant of muscle physiology. The mechanotransduction of strain and strain rate in C2C12 myoblasts were investigated utilizing a radiolabeled GTP analogue to detect stretch-induced GTP-bin
Publikováno v:
Biochemical and Biophysical Research Communications. 299:258-262
The endothelium is known to sense and respond to its physical environment, but the underlying mechanisms and early events of endothelial cell mechanotransduction are not well understood. The present study measured G protein activation by mechanical s
Autor:
Juan Sanchez-Esteban, Nicole Lee, Ophira Silbert, Benjamin S. Maciejewski, Yulian Wang, Nathan L. McKnight, John A. Frangos
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 291(4)
The signaling pathways by which mechanical forces modulate fetal lung development remain largely unknown. In the present study, we tested the hypothesis that strain-induced fetal type II cell differentiation is mediated via the cAMP signaling pathway
Autor:
Nicole Lee, Yulian Wang, Nathan L. McKnight, Benjamin S. Maciejewski, John A. Frangos, Juan Sanchez-Esteban, Ophira Silbert
Publikováno v:
The FASEB Journal. 20
The signaling pathways by which mechanical forces modulate fetal lung development remain largely unknown. In the present study, we tested the hypothesis that strain-induced fetal type II cell diffe...
Autor:
John A. Frangos, Nathan L. McKnight
Publikováno v:
Annals of biomedical engineering. 31(3)
Vascular smooth muscle cells (VSMCs) exist in a dynamic mechanical environment and can sense and respond to mechanical stimuli in vivo. Stretch is known to stimulate intracellular biochemical events, but the influence of the rate at which stretch is