A Validation Study of the Alcohol Related Neurodevelopmental Disorders Behavioral Checklist

Autor: Ann Marie O’Connell, Larry Burd, Marilyn G. Klug, Nathan L. Kobrinsky, Amanda Palme

Publikováno v: Alcoholism: Clinical and Experimental Research. 45:765-772

Background The initial confirmatory factor analysis of the Alcohol Related Neurodevelopmental Disorder Behavioral Checklist (ABC) utilized a population of 203 children. The analysis identified 10 independent measures (executive functioning, attention

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf240c3ff745babf45a20d285b5cec60
https://doi.org/10.1111/acer.14570

Urine Methotrexate Concentration at 46–48 Hours Post-Treatment Reflects Methotrexate-Induced Acute Kidney Injury

Autor: Jacob R. Greenmyer, Larry Burd, Nathan L. Kobrinsky

Publikováno v: J Pediatr Pharmacol Ther

Early identification of methotrexate-induced acute kidney injury (AKI) and delayed elimination of methotrexate are critical to limiting toxicity of the drug. The current monitoring strategy consists of serial serum methotrexate concentrations at 24,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27337a5fe301a5b04d4ee16f3e54882
https://europepmc.org/articles/PMC8021244/

Phase I trial of low-dose interleukin 2 therapy in patients with Wiskott-Aldrich syndrome

Autor: Lavesh A. Gwalani, Soma Jyonouchi, Chistopher Moertel, Maria Ahmad, Nathan L. Kobrinsky, Sumita Roy-Ghanta, Brenda Gwafila, Ji Young Kim, Cecil Holbert, Jordan S. Orange

Publikováno v: Clinical Immunology. 179:47-53

Background Low dose IL-2 can restore the function of T and NK cells from Wiskott-Aldrich (WAS) patients. However, the safety of in vivo IL-2 in WAS is unknown. Objectives A phase-I study to assess safety of low dose IL-2 in WAS. Methods Patients rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099ca43cc558b0bb8e84c6f083b26e4d
https://doi.org/10.1016/j.clim.2017.02.001

A Randomized Trial of Factor VIII and Neutralizing Antibodies in Hemophilia A

Autor: Kaan Kavakli, Mamta Manglani, Ezio Zanon, Christoph Male, Tarek Owaidah, Johnny Mahlangu, Ramabadran Varadarajan, Veronica Soto Arellano, Flora Peyvandi, Alessandra Nunes Loureiro Prezotti, Monica Martinez, Frits R. Rosendaal, Cecil Ross, Suresh Hanagavadi, Suvankar Majumdar, Bulent Zulfikar, Anupam Sachdeva, Brian M. Wicklund, Amal El-Beshlawy, Marilyn J. Manco-Johnson, M. Cerqueira, Dinesh M Nayak, Pier Mannuccio Mannucci, Santiago Bonanad Boix, Nadia P. Ewing, Klaus Schmitt, Angeles Palomo Bravo, Nathan L Kobrinsky, Maria Elisa Mancuso, Shashikant Apte, Mathew Thomas, Isabella Garagiola, Rogelio Paredes Aguilera, Guy Young, Maria Gabriella Mazzucconi, Esperanza Marzouka, Rosario Perez Garrido, Tulika Seth, Bülent Antmen, Mohsen Saleh Elalfy, Peyman Eshghi, E. Santagostino, Mindy L. Simpson, Vijay Ramanan, Daniela Neme, Mehran Karimi, Adriana C Sandoval Gonzalez

Publikováno v: New England Journal of Medicine, 374(21), 2054-2064
NEW ENGLAND JOURNAL OF MEDICINE
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname

WOS: 000376443500008
PubMed ID: 27223147
BACKGROUND The development of neutralizing anti-factor VIII alloantibodies (inhibitors) in patients with severe hemophilia A may depend on the concentrate used for replacement therapy. METHODS We con

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0706f075d71f088bb7ee2416552359
http://hdl.handle.net/1887/113139

Successful treatment of doxorubicin and cisplatin resistant hepatoblastoma in a child with Beckwith-Wiedemann syndrome with high dose acetaminophen and N -acetylcysteine rescue

Autor: Jacob A. Goldenberg, Diane E. Sjolander, Nathan L. Kobrinsky, Thomas C. Ortmeier

Publikováno v: Pediatric Blood & Cancer. 45:222-225

High dose acetaminophen (HDAC) with N-acetylcysteine (NAC) has been effective in adults with advanced malignancies. We report HDAC with NAC in a child with progressive hepatoblastoma, confirmed at biopsy of an unresectable hepatic mass. Alpha-fetopro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7656fe0f17f53622642c13de5524a9e1
https://doi.org/10.1002/pbc.20330