Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Nathan L, Alderson"'
Autor:
Nathan L. Alderson, Hiroko Hama
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1203-1208 (2009)
Sphingolipids are ubiquitous components of eukaryotic cells that regulate various cellular functions. In many cell types, a fraction of sphingolipids contain 2-hydroxy fatty acids, produced by fatty acid 2-hydroxylase (FA2H), as the N-acyl chain of c
Externí odkaz:
https://doaj.org/article/29ae817da63c493883a531bb9a00c642
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 153-161 (2008)
Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids. We recently reported that fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is the major
Externí odkaz:
https://doaj.org/article/f8b4b01bf1154ac4953caea7492e78d8
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 12, Pp 2772-2780 (2006)
2-Hydroxy fatty acids are relatively minor species of membrane lipids found almost exclusively as N-acyl chains of sphingolipids. In mammals, 2-hydroxy sphingolipids are uniquely abundant in myelin galactosylceramide and sulfatide. Despite the well-d
Externí odkaz:
https://doaj.org/article/46e0e224c84d4daca9bf0ff0cb56e463
Autor:
Andrzej S. Januszewski, Nathan L. Alderson, Alicia J. Jenkins, Suzanne R. Thorpe, John W. Baynes
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1440-1449 (2005)
Chemical modification of proteins by advanced glycation and lipoxidation end products is implicated in the pathogenesis of macrovascular disease in aging and diabetes. To identify biomarkers of the lipoxidative modification of protein, we studied the
Externí odkaz:
https://doaj.org/article/7c839f99536d448fba1d1fb10a849551
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 7, Pp 1569-1575 (2005)
Fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is an enzyme responsible for the de novo synthesis of sphingolipids containing 2-hydroxy fatty acids. 2-Hydroxy sphingolipids are highly abundant in the brain, as major myelin galactolipids (
Externí odkaz:
https://doaj.org/article/b313be916c344dd4b19a32b034c63be2
Autor:
Gabriel Virella, Suzanne R. Thorpe, Nathan L. Alderson, M. Brooks Derrick, Charlyne Chassereau, J. Matthew Rhett, Maria F. Lopes-Virella
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1859-1867 (2004)
Humans and laboratory animals recognize human modified LDL as immunogenic. Immune complexes (ICs) isolated from human sera contain malondialdehyde-modified LDL (MDA-LDL) and N ε(carboxymethyl)lysine-modified LDL (CML-LDL) as well as antibodies react
Externí odkaz:
https://doaj.org/article/849fa92d82034bf7958d07475752ed3f
Autor:
Gabriel Virella, Suzanne R. Thorpe, Nathan L. Alderson, Elias M. Stephan, Daniel Atchley, Francesco Wagner, Maria F. Lopes-Virella
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 487-493 (2003)
Advanced glycosylation end-products (AGEs) are believed to play a significant role in the development of vascular complications in diabetic patients. One such product, AGE-LDL, has been shown to be immunogenic. In this report, we describe the isolati
Externí odkaz:
https://doaj.org/article/5f8ef3b78c5e4cc3b193093b6cdf380c
Autor:
Jacek Bielawski, S. Michal Jazwinski, Rashna Bhandari, Solomon H. Snyder, Nathan L. Alderson, Besim Ogretmen, James C. Jiang, Hiroko Hama, Suriyan Ponnusamy
Publikováno v:
Journal of Biological Chemistry. 283:27514-27524
In this study, we investigated the roles of very long-chain fatty acid (VLCFA) synthesis by fatty acid elongase 3 (ELO3) in the regulation of telomere length and life span in the yeast Saccharomyces cerevisiae. Loss of VLCFA synthesis via deletion of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66968cb849d1d9facc8a59002737e661
https://doi.org/10.1074/jbc.m802980200
https://doi.org/10.1074/jbc.m802980200
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 153-161 (2008)
Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids. We recently reported that fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is the major
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1ffece46ac22d4ebda98617c375c35
http://www.sciencedirect.com/science/article/pii/S0022227520428901
http://www.sciencedirect.com/science/article/pii/S0022227520428901
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 12, Pp 2772-2780 (2006)
2-Hydroxy fatty acids are relatively minor species of membrane lipids found almost exclusively as N-acyl chains of sphingolipids. In mammals, 2-hydroxy sphingolipids are uniquely abundant in myelin galactosylceramide and sulfatide. Despite the well-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f7c293740153038b161785bde165de
http://www.sciencedirect.com/science/article/pii/S0022227520432699
http://www.sciencedirect.com/science/article/pii/S0022227520432699