Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nathan J. Redlich"'
Autor:
Todd VanArsdale, Brian A. Van Tine, Loren S. Michel, Anthony M. Robinson, Douglas Adkins, Nathan J. Redlich, Richa Rathore
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 11, Pp 1-13 (2019)
Cell Death and Disease, Vol 10, Iss 11, Pp 1-13 (2019)
The loss of p16 is a signature event in Human Papilloma Virus (HPV)-negative head and neck squamous cell carcinoma (HNSCC) that leads to increased Cyclin Dependent Kinase 4/6 (CDK) signaling. Palbociclib, a CDK4/6 inhibitor, is active for the treatme
Autor:
Jason M. Held, John S. Bomalaski, Matthew Schultze, Bethany C. Prudner, Loren S. Michel, Laura M. Shelton, Kenjiro Kami, Megan D. Radyk, S.S. Lange, Shin-Cheng Tzeng, Jeff Kremer, Gregory R. Bean, Caitlyn B. Brashears, Aixiao Li, Jon McConathy, Zack Morgan, Nathan J. Redlich, Brian A. Van Tine, Takashi Tsukamoto
Publikováno v:
Cell Reports, Vol 18, Iss 4, Pp 991-1004 (2017)
Cell reports
Cell reports
SUMMARY Targeting defects in metabolism is an underutilized strategy for the treatment of cancer. Arginine auxotrophy resulting from the silencing of argininosuccinate synthetase 1 (ASS1) is a common metabolic alteration reported in a broad range of
Publikováno v:
Journal of shoulder and elbow surgery. 28(3)
Background Recent orthopedic research has questioned the effect of opioid use on surgical outcomes. This study investigated this in the context of arthroscopic rotator cuff repair. We hypothesized that preoperative opioid use would be associated with
Autor:
Randall J. Kimple, Kwangok P. Nickel, Ravindra Uppaluri, Loren S. Michel, Anthony M. Robinson, Brian A. Van Tine, Douglas Adkins, Nathan J. Redlich, Deric L. Wheeler, Andrew P. Stein
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 1, Pp 1-12 (2018)
Cell Death and Disease, Vol 9, Iss 1, Pp 1-12 (2018)
ErbB3 has been widely implicated in treatment resistance, but its role as a primary treatment target is less clear. Canonically ErbB3 requires EGFR or ErbB2 for activation, whereas these two established treatment targets are thought to signal indepen