Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Nathan J. Charles"'
Publikováno v:
Academic Forensic Pathology. 5:161-168
Autor:
Daniel F. Boyer, Nathan J. Charles
Publikováno v:
Archives of pathologylaboratory medicine. 141(11)
Mixed-phenotype acute leukemia (MPAL) is a heterogeneous category in the World Health Organization classification that comprises acute leukemias with discrete admixed populations of myeloid and lymphoid blasts (“bilineal”) or with extensive coexp
Autor:
Peter A. Argenta, Steve E. Kalloger, C. Blake Gilks, Caroline H. Diep, Carol A. Lange, Nathan J. Charles
Publikováno v:
Cell Cycle. 12:1433-1449
Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However, PR are abundantly expressed in a significant percentage of serous and endometrioid ovarian tumors; pa
Autor:
Nathan J. Charles, Kathryn L. Schwertfeger, Gwen E. Dressing, Jodi E. Goldberg, Carol A. Lange
Publikováno v:
Steroids. 76:11-17
The recent discovery of a novel, membrane localized progestin receptor (mPR) unrelated to the classical progesterone receptor (PR) in fishes and its subsequent identification in mammals suggests a potential mediator of non-traditional progestin actio
Publikováno v:
Hormones and Cancer. 1:167-176
The high mortality rates associated with ovarian cancer are largely due to a lack of highly effective treatment options for advanced stage disease; a time when initial diagnosis most commonly occurs. Recent evidence suggests that the steroid hormone,
Autor:
Ryszard T. Smolenski, Paul J.R. Barton, James E. Rider, Sangjin Lee, Cesare M. Terracciano, Nathan J. Charles, George M Tadros, Ami Mariash, Emma J. Birks, Jenna Stangland, Leslie W. Miller, Magdi H. Yacoub, Neeta Adhikari, Jennifer L. Hall, Sean P. Polster
Publikováno v:
Journal of Cardiovascular Translational Research. 2:182-190
The purpose of this study was to determine the effects of chronic treatment with the beta 2 adrenergic receptor agonist clenbuterol on endothelial progenitor cells (EPC) in a well-characterized model of heart failure, the muscle LIM protein knockout
Autor:
Nathan J. Charles, Martin E. Cullen, Leslie W. Miller, Magdi H. Yacoub, Neeta Adhikari, Jennifer L. Hall, Emma J. Birks, Subash Harwalker, Paul J.R. Barton, Ami Mariash, Robert S. George, Suzanne Grindle, Leanne E. Felkin, James E. Rider, Sangjin Lee, Sean P. Polster
Publikováno v:
European Heart Journal. 28:613-627
Aims A novel combination therapy consisting of a left ventricular assist device (LVAD) combined with pharmacologic therapy including the selective b2-agonist, clenbuterol, has shown promise in restoring ventricular function in patients with heart fai
Autor:
David Schuweiler, Elizabeth A. Braunlin, James E. Rider, Sangjin Lee, Ami Mariash, Robert C. Huebert, Maggie Robledo, Neeta Adhikari, Sean P. Polster, Jennifer L. Hall, Nathan J. Charles
The mitogen activated protein kinase (MAPK) signaling pathway regulates multiple events leading to heart failure including ventricular remodeling, contractility, hypertrophy, apoptosis, and fibrosis. The regulation of conserved intrinsic inhibitors o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92106dce8266dd31e6cf64c7188d9bd5
https://europepmc.org/articles/PMC2923832/
https://europepmc.org/articles/PMC2923832/
Publikováno v:
Current atherosclerosis reports. 8(3)
Our understanding of the molecular signaling pathways regulating the initiation and progression of atherosclerosis or remodeling in response to injury has begun to cross the boundaries from regulation of well-described canonical pathways to the inter
Autor:
Sofia Ormaza, David Fermin, Nathan J. Charles, Robert C. Huebert, Soon J. Park, Leslie W. Miller, Neeta Adhikari, Mohammed Karim Ezzat, Suzanne Grindle, Qinglu Li, Xinqiang Han, Jennifer L. Hall
Publikováno v:
Physiological genomics. 18(3)
We screened a compendium of gene profiles from 19 paired human heart samples harvested at the time of implant and explant of a left ventricular assist device (LVAD) for novel genes regulating the Ras/MEK/ERK cascade. From this analysis we identified