Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nathan J, Nadolski"'
Autor:
Paul W. Chrystal, Nils J. Lambacher, Lance P. Doucette, James Bellingham, Elena R. Schiff, Nicole C. L. Noel, Chunmei Li, Sofia Tsiropoulou, Geoffrey A. Casey, Yi Zhai, Nathan J. Nadolski, Mohammed H. Majumder, Julia Tagoe, Fabiana D’Esposito, Maria Francesca Cordeiro, Susan Downes, Jill Clayton-Smith, Jamie Ellingford, Genomics England Research Consortium, Omar A. Mahroo, Jennifer C. Hocking, Michael E. Cheetham, Andrew R. Webster, Gert Jansen, Oliver E. Blacque, W. Ted Allison, Ping Yee Billie Au, Ian M. MacDonald, Gavin Arno, Michel R. Leroux
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
Motile and non-motile cilia have distinct functions and protein complexes associated with them. Here, the authors show the conserved protein CFAP20 is important for both motile and non-motile cilia and is distinct from other ciliopathy-associated dom
Externí odkaz:
https://doaj.org/article/a85ce5f9aafc4ed1a65a7a9f8a648d61
Publikováno v:
Cells, Vol 9, Iss 10, p 2214 (2020)
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa. RP1L1
Externí odkaz:
https://doaj.org/article/e86e253ed5884adaa329bf0b6f35e705
Autor:
Patricia L. A. Leighton, Nathan J. Nadolski, Adam Morrill, Trevor J. Hamilton, W. Ted Allison
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
The misfolding of cellular prion protein (PrPC) to form PrP Scrapie (PrPSc) is an exemplar of toxic gain-of-function mechanisms inducing propagated protein misfolding and progressive devastating neurodegeneration. Despite this, PrPC function in the b
Externí odkaz:
https://doaj.org/article/1d2901a309af40dc8e56f539975a41a3
Publikováno v:
Documenta Ophthalmologica. 142:99-109
The electroretinogram (ERG) is a powerful approach for investigating visual function in zebrafish ocular disease models. However, complexity, cost, and a literature gap present as significant barriers for the introduction of this technology to new ze
Publikováno v:
Cells, Vol 9, Iss 2214, p 2214 (2020)
Cells
Volume 9
Issue 10
Cells
Volume 9
Issue 10
Photoreceptor disease results in irreparable vision loss and blindness, which has a dramatic impact on quality of life. Pathogenic mutations in RP1L1 lead to photoreceptor degenerations such as occult macular dystrophy and retinitis pigmentosa. RP1L1
Publikováno v:
Documenta ophthalmologica. Advances in ophthalmology. 142(1)
The electroretinogram (ERG) is a powerful approach for investigating visual function in zebrafish ocular disease models. However, complexity, cost, and a literature gap present as significant barriers for the introduction of this technology to new ze
Autor:
Nathan J. Nadolski, Jennifer C. Hocking, Andrew J. Waskiewicz, Spencer D. Balay, Casey X. L. Wong
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Analysis of photoreceptor morphology and gene expression in mispatterned eyes of zebrafish growth differentiation factor 6a (gdf6a) mutants. Methods Rod and cone photoreceptors were compared between gdf6a mutant and control zebrafish from lar
Publikováno v:
Biology Open, Vol 7, Iss 1 (2018)
Biology Open
Biology Open
The misfolding of cellular prion protein (PrPC) to form PrP Scrapie (PrPSc) is an exemplar of toxic gain-of-function mechanisms inducing propagated protein misfolding and progressive devastating neurodegeneration. Despite this, PrPC function in the b