Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nathan Ing"'
Autor:
Kenneth H. Gouin, Nathan Ing, Jasmine T. Plummer, Charles J. Rosser, Bassem Ben Cheikh, Catherine Oh, Stephanie S. Chen, Keith Syson Chan, Hideki Furuya, Warren G. Tourtellotte, Simon R. V. Knott, Dan Theodorescu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
The identification of response biomarkers for surgery, chemotherapy and immune checkpoint therapy in bladder cancer is crucial. Here, single nuclei RNA sequencing and spatial profiling identify a cancer cell population expressing Neural Type Cadherin
Externí odkaz:
https://doaj.org/article/5b25f04e5b884ae4a0e99e6169061c15
Autor:
Nathan Ing, Fangjin Huang, Andrew Conley, Sungyong You, Zhaoxuan Ma, Sergey Klimov, Chisato Ohe, Xiaopu Yuan, Mahul B. Amin, Robert Figlin, Arkadiusz Gertych, Beatrice S. Knudsen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Gene expression signatures are commonly used as predictive biomarkers, but do not capture structural features within the tissue architecture. Here we apply a 2-step machine learning framework for quantitative imaging of tumor vasculature to
Externí odkaz:
https://doaj.org/article/734bffa0c8884685a89d36929e58ac7d
Autor:
Florian Raths, Mehran Karimzadeh, Nathan Ing, Andrew Martinez, Yoona Yang, Ying Qu, Tian-Yu Lee, Brianna Mulligan, Suzanne Devkota, Wayne T. Tilley, Theresa E. Hickey, Bo Wang, Armando E. Giuliano, Shikha Bose, Hani Goodarzi, Edward C. Ray, Xiaojiang Cui, Simon R.V. Knott
Publikováno v:
Cell Genomics. 3:100272
Autor:
Charles J. Rosser, Dan Theodorescu, Kenneth Gouin, Warren G. Tourtellotte, Simon R.V. Knott, Bassem Ben Cheikh, Jasmine T. Plummer, Hideki Furuya, Keith S. Chan, Catherine Oh, Stephanie S. Chen, Nathan Ing
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Neoadjuvant chemotherapy (NAC) prior to surgery and immune checkpoint therapy (ICT) have revolutionized bladder cancer management. However, stratification of patients that would benefit most from these modalities remains a major clinical challenge. H
Publikováno v:
Genes, Vol 15, Iss 7, p 939 (2024)
Genome-wide association studies (GWAS) have accelerated the exploration of genotype–phenotype associations, facilitating the discovery of replicable genetic markers associated with specific traits or complex diseases. This narrative review explores
Externí odkaz:
https://doaj.org/article/52d28fcdd02646e2b6b0287ba59d3359
Autor:
Eric N. Miller, Arash Amighi, Beatrice S. Knudsen, Michael T. Lewis, Arkadiusz Gertych, Fangjin Huang, Nathan Ing, Isla P. Garraway
Publikováno v:
Journal of Urology. 201
INTRODUCTION AND OBJECTIVES:Conventional histological analysis cannot differentiate diagnostic prostate needle biopsies (PNBX) from patients with localized disease (stage M0) versus those with de n...
Autor:
Arkadiusz Gertych, Samuel Guzman, Tomasz Markiewicz, Beatrice S. Knudsen, Zaneta Swiderska-Chadaj, Zhaoxuan Ma, Hootan Salemi, Szczepan Cierniak, Nathan Ing, Ann E. Walts
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
During the diagnostic workup of lung adenocarcinomas (LAC), pathologists evaluate distinct histological tumor growth patterns. The percentage of each pattern on multiple slides bears prognostic significance. To assist with the quantification of growt
Autor:
Tomasz Markiewicz, Beatrice S. Knudsen, Ann E. Walts, Szczepan Cierniak, Zhaoxuan Ma, Arkadiusz Gertych, Nathan Ing, Malgorzata Lorent, Zaneta Swiderska-Chadaj
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9783030237615
ITIB
ITIB
Patch-based image classification approaches are frequently employed in digital pathology applications with the goal to automatically delineate diagnostically important regions in digital slides. However, patches into which a slide is partitioned are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fc1b25ee6304ee82af2ade186e0eb6f
https://doi.org/10.1007/978-3-030-23762-2_2
https://doi.org/10.1007/978-3-030-23762-2_2
Autor:
Arkadiusz Gertych, Dermot P.B. McGovern, Hootan Salemi, Beatrice S. Knudsen, Nathan Ing, Zhaoxuan Ma, Zaneta Swiderska-Chadaj
Publikováno v:
Advances in Intelligent Systems and Computing ISBN: 9783319912103
ITIB
ITIB
Robust delineation of tissue components in hematoxylin and eosin (H&E) stained slides is a critical step in quantifying tissue morphology. Fully convolutional neural networks (FCN) are ideally suited for automatic and efficient segmentation of tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba28b7949f1950b15ff3508ee4262639
https://doi.org/10.1007/978-3-319-91211-0_34
https://doi.org/10.1007/978-3-319-91211-0_34
Autor:
Nathan Ing, Beatrice S. Knudsen, Arkadiusz Gertych, Hootan Salemi, Jiayun Li, Corey W. Arnold, Zhaoxuan Ma
Publikováno v:
Medical Imaging: Digital Pathology
Certain pathology workflows, such as classification and grading of prostate adenocarcinoma according to the Gleason grade scheme, stand to gain speed and objectivity by incorporating contemporary digital image analysis methods. We compiled a dataset