Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Nathan I. Walton"'
Autor:
Hung Caohuy, Ofer Eidelman, Tinghua Chen, Ognoon Mungunsukh, Qingfeng Yang, Nathan I. Walton, Bette S. Pollard, Sara Khanal, Shannon Hentschel, Catalina Florez, Andrew S. Herbert, Harvey B. Pollard
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract SARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper-proinflammatory state involves activation of signaling by NFκB, and unexpectedly, EN
Externí odkaz:
https://doaj.org/article/7a2225a402c0400ca2a99fa970f2b2ac
Publikováno v:
Colloids and Interfaces, Vol 8, Iss 2, p 18 (2024)
Silica nanoparticles synthesized solely from organosilanes naturally possess a greater number of organic functionalities than silica nanoparticles surface-modified with organosilanes. We report the synthesis of organically modified silica (ORMOSIL) n
Externí odkaz:
https://doaj.org/article/aa09e770517c465fa4d1194e3b9c15b2
Autor:
Hung Caohuy, Ofer Eidelman, Tinghua Chen, Shufeng Liu, Qingfeng Yang, Alakesh Bera, Nathan I. Walton, Tony T. Wang, Harvey B. Pollard
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract To initiate SARS-CoV-2 infection, the Receptor Binding Domain (RBD) on the viral spike protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2-expressing cells. We hypothesized that cardiac glycoside drugs might
Externí odkaz:
https://doaj.org/article/2ea2813bebb54bb3b57a27ab3d2f0753
Autor:
Nathan I. Walton, Xijun Zhang, Anthony R. Soltis, Joshua Starr, Clifton L. Dalgard, Matthew D. Wilkerson, Douglas Conrad, Harvey B. Pollard
Publikováno v:
Physiological Reports, Vol 9, Iss 11, Pp n/a-n/a (2021)
Abstract Cystic fibrosis (CF) is a life‐limiting autosomal recessive genetic disease caused by variants in the CFTR gene, most commonly by the [F508del] variant. Although CF is a classical Mendelian disease, genetic variants in several modifier gen
Externí odkaz:
https://doaj.org/article/7bad757c514f45c1b96f79c5d85631a5
Autor:
Hung Caohuy, Ofer Eidelman, Tinghua Chen, Qingfeng Yang, Bette S. Pollard, Nathan I. Walton, Harvey B. Pollard
BackgroundSARS-CoV-2-contributes to sickness and death in COVID-19 patients partly by inducing a hyper-proinflammatory immune response in the host airway. This hyper- proinflammatory state involves activation of signaling by NFκB and ENaC, and expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f3c8bafa03c876a9591855496bdd661
https://doi.org/10.1101/2022.01.18.476803
https://doi.org/10.1101/2022.01.18.476803
Autor:
Tinghua Chen, Hung Caohuy, Qingfeng Yang, Harvey B. Pollard, Nathan I. Walton, Alakesh Bera, Shufeng Liu, Ofer Eidelman, Tony T. Wang
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
To initiate SARS-CoV-2 infection, the Receptor Binding Domain (RBD) on the viral spike protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2-expressing cells. We hypothesized that cardiac glycoside drugs might block th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79116554b6b2b55e64fff5aaf6530619
https://doi.org/10.1038/s41598-021-01690-9
https://doi.org/10.1038/s41598-021-01690-9
Autor:
Nathan I. Walton, Alakesh Bera, Qingfeng Yang, Harvey B. Pollard, Ofer Eidelman, Hung Caohuy, Tinghua Chen
To initiate SARS-CoV-2 infection, the Receptor Binding Domain (RBD) on the viral spike protein must first bind to the host receptor ACE2 protein on pulmonary and other ACE2-expressing cells. We hypothesized that cardiac glycoside drugs might block th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58a21f29e0650ab1f1ec783b7f31056d
https://doi.org/10.1101/2021.06.02.446343
https://doi.org/10.1101/2021.06.02.446343
Publikováno v:
Journal of Nanoparticle Research. 20
Water dispersible boron nanoparticles have great potential as materials for boron neutron capture therapy of cancer and magnetic resonance imaging, if they are prepared on a large scale with uniform size and shape and hydrophilic modifiable surface.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::748bc5a1742260701f479afd650f428d
https://doi.org/10.1007/s11051-018-4220-8
https://doi.org/10.1007/s11051-018-4220-8
Publikováno v:
J. Mater. Chem.. 22:877-882
We developed a method to obtain water-dispersible boron nanoparticles (BNPs) as a potential boron delivery agent for cancer treatment. The 40 nm nanoparticles are prepared by mechanical milling in undecylenic acid followed by ligand exchange with dop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::757d6eb325582829ec5fbb75301974fc
https://doi.org/10.1039/c1jm12655e
https://doi.org/10.1039/c1jm12655e
Publikováno v:
MRS Proceedings. 1625
We prepared organically modified silica (ORMOSIL) nanoparticles with internal functional groups and mesoporosity, suitable for the incorporation of modalities for both MRI imaging and cancer treatment by neutron capture therapy using gadolinium-157 n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd412e023aa7e93aa6ba0e15743229be
https://doi.org/10.1557/opl.2014.215
https://doi.org/10.1557/opl.2014.215