Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nathan Heald"'
Autor:
Sindy Liao-Chan, Barbara Daine-Matsuoka, Nathan Heald, Tiffany Wong, Tracey Lin, Allen G Cai, Michelle Lai, Joseph A D'Alessio, Jan-Willem Theunissen
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0124708 (2015)
Antibodies against cell surface antigens may be internalized through their specific interactions with these proteins and in some cases may induce or perturb antigen internalization. The anti-cancer efficacy of antibody-drug conjugates is thought to r
Externí odkaz:
https://doaj.org/article/36d07d62512441548835e2f6c9405095
Autor:
Stephen L. Hauser, William C. Mobley, Stefan Fisher, Daniel P. Rosenberg, Claude P. Genain, Ilse Bartke, Jürgen W. Unger, Nathan Heald, Steven W. Cheung, Pablo Villoslada
Publikováno v:
The Journal of experimental medicine, vol 191, iss 10
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Multiple sclerosis is a demyelinating disorder of the central nervous system (CNS), in which an immune attack directed against myelin constituents causes myelin destruction and death of oligodendrocytes, the myelin-producing cells. Here, the efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243d0b99f93f80b41e210f3a771600f9
https://doi.org/10.1084/jem.191.10.1799
https://doi.org/10.1084/jem.191.10.1799
Autor:
Rajana Bautista, Alison H. Joly, Donghui Huang, Wentao Zhang, Yongchang Shi, Leanne Goon, Marcus Zuzow, Peter Lamb, Peiwen Yu, Felix Chu, Valentina Vysotskaia, Belinda Cancilla, Lora Zhao, Stefan Engst, Frauke Bentzien, Nathan Heald, Anna Gibson, F. Michael Yakes
Publikováno v:
Thyroid : official journal of the American Thyroid Association. 23(12)
A limited number of approved therapeutic options are available to metastatic medullary thyroid cancer (MTC) patients, and the response to conventional chemotherapy and/or radiotherapy strategies is inadequate. Sporadic and inherited mutations in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99b0c41032da7e931f8fac6e662b9ba
https://pubmed.ncbi.nlm.nih.gov/23705946
https://pubmed.ncbi.nlm.nih.gov/23705946
Autor:
Robert Henschel, Stephen Simms, David Hancock, Scott Michael, Tom Johnson, Nathan Heald, Thomas William, Donald Berry, Matt Allen, Richard Knepper, Matthew Davy, Matthew Link, Craig A. Stewart
Publikováno v:
2012 International Conference for High Performance Computing, Networking, Storage and Analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f7d93832fbab19d0e2a463585d616ab
https://doi.org/10.1109/sc.2012.43
https://doi.org/10.1109/sc.2012.43
Discovery of a novel series of potent and orally bioavailable phosphoinositide 3-kinase γ inhibitors
Autor:
Charles R. Holst, Timothy Patrick Forsyth, Peter Lamb, Christopher Jaeger, Arthur Plonowski, Longcheng Wang, Julie Lougheed, John M. Nuss, Michael Yakes, Tae-Gon Baik, Matthew Sangyup Lee, Xiang Wu, Chris A. Buhr, Scott Lam, Olivia Raeber, Henry Johnson, Joon Won Jeong, Nathan Heald, Kevin Noson, Eric Brooks, Leanne Goon, Joanne Song, Lam Nguyen, Jonah Cannoy, Paul Foster, Sunghoon Ma, Matthew A. Williams, Byung Gyu Kim, Thomas J. Stout, James W. Leahy, Wentao Zhang, Peiwen Yu
Publikováno v:
Journal of medicinal chemistry. 55(11)
The phosphoinositide 3-kinases (PI3Ks) have been linked to an extraordinarily diversified group of cellular functions making these enzymes compelling targets for the treatment of disease. A large body of evidence has linked PI3Kγ to the modulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43105d445d7cec8eb97fa3b7836d021f
https://pubmed.ncbi.nlm.nih.gov/22548342
https://pubmed.ncbi.nlm.nih.gov/22548342
Autor:
Steve Copp, A Kennedy, Sue K. Hageman, David C. Poole, Julie Ryans, Nathan Heald, Fady I. Malik, T I. Musch, Arash Pakdel, Jeffrey R. Jasper
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60bbf0a80d0209936abfd05010ca8501
https://doi.org/10.1096/fasebj.26.1_supplement.1121.7
https://doi.org/10.1096/fasebj.26.1_supplement.1121.7
Autor:
Nathan Heald, Robert Goertsches, Pablo Villoslada, Claude P. Genain, Stephen L. Hauser, Kristina Abel
Publikováno v:
European journal of immunology. 31(10)
Auto-reactive T cells present in healthy subjects remain in a state of unresponsiveness, but may trigger autoimmunity under various situations. Although myelin oligodendrocyte glycoprotein (MOG) is a potential target antigen in multiple sclerosis (MS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58b80948e12d7aa6dbcbffe44a0f4f38
https://pubmed.ncbi.nlm.nih.gov/11592070
https://pubmed.ncbi.nlm.nih.gov/11592070
Autor:
Ilse Bartke, Stephen L. Hauser, Nathan Heald, Claude P. Genain, Jurgen Unger, P. Diaz-Villoslada
Publikováno v:
Journal of Neuroimmunology. 90:55
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::375684a8042614eede0512fa933b72b3
https://doi.org/10.1016/s0165-5728(98)91508-9
https://doi.org/10.1016/s0165-5728(98)91508-9