Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nathan Haselton"'
Autor:
Travis C. Palmer, Gavril W. Pasternak, Nathan Haselton, András Váradi, Valerie Le Rouzic, Joan J. Subrath, Attila Borics, Susruta Majumdar, Amanda Hunkele, Gina F. Marrone, Daniel Afonin
Publikováno v:
ACS Chemical Neuroscience. 6:1570-1577
We report a novel approach to synthesize carfentanil amide analogues utilizing the isocyanide-based four-component Ugi multicomponent reaction. A small library of bis-amide analogues of carfentanil was created using N-alkylpiperidones, aniline, propi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4325f9563198222495feb34e0262e2a9
https://doi.org/10.1021/acschemneuro.5b00137
https://doi.org/10.1021/acschemneuro.5b00137
Autor:
Thomas Lectka, Steven Bloom, Maxime A. Siegler, Nathan Haselton, Jake Jaffe, Michael T. Scerba
Publikováno v:
The Journal of Organic Chemistry. 77:1605-1609
We describe the synthesis and preliminary study of two molecules, in which a fluorine atom is positioned proximately above the π-orbitals of a C═C bond or else wherein a C-F bond interacts in a "head on" fashion with a proximate C-H bond. The spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3e530b72ee158029d1fd035df1afe3
https://doi.org/10.1021/jo2024152
https://doi.org/10.1021/jo2024152
Autor:
Nathan Haselton, Anna R. Pasternak, Susruta Majumdar, Gavril W. Pasternak, Julia Ocampo, Steven G. Grinnell, Maxim Burgman
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:4001-4004
Tritiated opioid radioligands have proven valuable in exploring opioid binding sites. However, tritium has many limitations. Its low specific activity and limited counting efficiency makes it difficult to examine low abundant, high affinity sites and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8965f7a8c53c56745bccfa4a93472818
https://doi.org/10.1016/j.bmcl.2011.05.008
https://doi.org/10.1016/j.bmcl.2011.05.008
Autor:
Thomas Lectka, Steven Bloom, Maxwell Gargiulo Holl, Nathan Haselton, Cody Ross Pitts, Ellen Urheim, David C. Miller
Publikováno v:
ChemInform. 44
The selective incorporation of fluorine into organic molecules is achieved using Selectfluor in combination with a three-component catalytic system.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a2d80ea42e4291554e0ff1dd87919c
https://doi.org/10.1002/chin.201312026
https://doi.org/10.1002/chin.201312026
Autor:
Susruta Majumdar, Gavril W. Pasternak, Nathan Haselton, Ying-Xian Pan, Julie Ocampo, Anna R. Pasternak, Steven G. Grinnell, Kuni Nagakura, Lisa Polikar, Maxim Burgman, Valerie Le Rouzic, Joan J. Subrath
3-Iodobenzoylnaltrexamide 1 (IBNtxA) is a potent analgesic acting through a novel receptor target that lack many side-effects of traditional opiates composed, in part, of exon 11-associated truncated six transmembrane domain MOR-1 (6TM/E11) splice va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88f0f108e54f15be05eb51405ae7ed3
https://europepmc.org/articles/PMC3412067/
https://europepmc.org/articles/PMC3412067/
Autor:
Maxwell Gargiulo Holl, David C. Miller, Nathan Haselton, Ellen Urheim, Thomas Lectka, Cody Ross Pitts, Steven Bloom
Publikováno v:
Angewandte Chemie (International ed. in English). 51(42)
A group effort: Reported is the title reaction using a polycomponent catalytic system involving commercially available Selectfluor, a putative radical precursor N-hydroxyphthalimide, an anionic phase-transfer catalyst (KB(C(6)F(5))(4)), and a copper(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b70596b402ee850ea4fb6dab154765c
https://pubmed.ncbi.nlm.nih.gov/22976771
https://pubmed.ncbi.nlm.nih.gov/22976771